Results 51 to 60 of about 118,715 (309)

Special Issue on IberSPEECH 2022: Speech and Language Technologies for Iberian Languages

Applied Sciences
ThisSpecial Issue presents the latest advances in research and novel applications of speech and language technologies based on the works presented at the sixth edition of the IberSPEECH conference held in Granada in 2022, paying special attention to ...
José L. Pérez-Córdoba, Francesc Alías-Pujol, Zoraida Callejas   +2 more
doaj   +1 more source

Lexical-perceptual integration influences sensorimotor adaptation in speech

Frontiers in Human Neuroscience, 2014
A combination of lexical bias and altered auditory feedback was used to investigate the influence of higher-order linguistic knowledge on the perceptual aspects of speech motor control. Subjects produced monosyllabic real words or pseudo-words containing
Nicolas Jean Bourguignon, Nicolas Jean Bourguignon, Nicolas Jean Bourguignon, Shari R. Baum, Shari R. Baum, Douglas M Shiller, Douglas M Shiller, Douglas M Shiller   +7 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Acoustic Analysis of Fricatives /s/ and /ʃ/ and Affricate /ʧ/ in Persian-Speaking Cochlear-Implanted Children and Normal-Hearing Peers

Auditory and Vestibular Research
Background and Aim: Hearing-impaired individuals have difficulty comprehending and producing speech sounds. Cochlear implantation is used to augment hearing. The present study aims to compare the production of fricatives /s/ and /ʃ/ and affricate /ʧ/ by
Rahimeh Roohparvar, Mahin Karimabadi, Shima Ghahari, Mogaddameh Mirzaee   +3 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Perception of smiling voice in spontaneous speech synthesis

, 2021
Smiling during speech production has been shown to result in perceptible acoustic differences compared to non-smiling speech. However, there is a scarcity of research on the perception of “smiling voice” in synthesized spontaneous speech.
Székely, Éva, Gustafsson, Joakim,, Kirkland, Ambika, Gustafsson, Joakim, Székely, Éva,, Włodarczak, Marcin,, Kirkland, Ambika,, Włodarczak, Marcin   +7 more
core   +1 more source

The role of syllables in sign language production

Frontiers in Psychology, 2014
The aim of the present study was to investigate the functional role of syllables in sign language and how the different phonological combinations influence sign production. Moreover, the influence of age of acquisition was evaluated. Deaf signers (native
Cristina eBaus, Eva eGutiérrez, Manuel eCarreiras, Manuel eCarreiras, Manuel eCarreiras   +4 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Characterizing intonation deficit in motor speech disorders : an autosegmental-metrical analysis of spontaneous speech in hypokinetic dysarthria, ataxic dysarthria and foreign accent syndrome

, 2012
The autosegmental-metrical (AM) framework represents an established methodology for intonational analysis in unimpaired speaker populations but has found little application in describing intonation in motor speech disorders (MSDs).
Lowit, Anja, Anja Kuschmann, Anja Lowit, Kuschmann, Anja   +3 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source