Results 71 to 80 of about 6,921,546 (301)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

The Effect of Lexical Cohort Size Is Independent of Semantic Context Effects in a Picture–Word Interference Task: A Combined ERP and sLORETA Study

open access: yesFrontiers in Human Neuroscience, 2019
Lexical cohort size is known to play an important role in the magnitude of semantic interference during picture naming in continuous and blocking naming tasks.
Mingkun Ouyang, Xiao Cai, Qingfang Zhang
doaj   +1 more source

The Effect of Semantic Context on Lexical Access in Children With and Without Developmental Language Disorder [PDF]

open access: yesIranian Rehabilitation Journal, 2023
Objectives: Lexical access problems are one of the limitations observed in children with developmental language disorders during the initial years of schooling. Semantic context has a powerful influence on lexical access.
Fatemeh Hassanati   +4 more
doaj  

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Lombard speech synthesis using transfer learning in a Tacotron text-to-speech system

open access: yes, 2019
Currently, there is increasing interest to use sequence-to-sequence models in text-to-speech (TTS) synthesis with attention like that in Tacotron models.
Bajibabu Bollepalli   +5 more
core   +1 more source

The relationship between speech perception, speech production, and vocabulary abilities in children : insights from by-group and continuous analyses

open access: yes, 2023
Purpose: The purpose of this study was to explore the relationship between speech perception, speech production, and vocabulary abilities in children with and without speech sound disorders (SSDs), analyzing the data both by group and continuously.Method:
Munro, Natalie   +5 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

The Edinburgh Speech Production Facility DoubleTalk Corpus [PDF]

open access: yes, 2013
The DoubleTalk articulatory corpus was collected at the Edinburgh Speech Production Facility (ESPF) using two synchronized Carstens AG500 electromagnetic articulometers.
Geng, Christian   +5 more
core   +4 more sources

The effect of accurate speech production experience on the development of auditory-visual speech perception in children

open access: yes, 2006
This study investigated the development of auditory-visual speech perception (AVSP) in a group of children with and without inconsistent phonological disorder, a speech production disorder.
Erdener, Dogu   +3 more
core  

Dysarthric speech classification using glottal features computed from non-words, words and sentences

open access: yes, 2018
Dysarthria is a neuro-motor disorder resulting from the disruption of normal activity in speech production leading to slow, slurred and imprecise (low intelligible) speech.
Narendra N P   +3 more
core   +1 more source

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