Results 101 to 110 of about 473,453 (298)

The Persistence of language Disorders in a Group of Disadvantaged Grade 3 Learners

open access: yesSouth African Journal of Communication Disorders, 2007
A strong correlation between early language impairment and academic failure has been suggested by past research. This follow-up cohort study of 25 monolingual, disadvantaged grade 3 learners investigated whether the language impairments diagnosed in ...
Daleen Klop, Seppo K. Tuomi
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

The Inclusion of Music Therapy in Speech-Language Interventions [PDF]

open access: yes, 2015
The purpose of this study was to investigate the inclusion of music in speech-language therapy. One hundred practicing speech-language pathologists (SLPs) participated in the study.
Farnell, Torry
core   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

The motivational climate perceived by young soccer players regarding their coaches, parents, and peers on sport optimal functioning: a cluster analysis

open access: yesFrontiers in Psychology
The aim of this study was (a) to describe the perceived motivational climate profiles created by coaches, parents, and peers of young football players, and (b) to analyse the implications of these profiles on goal orientations, motivation, psychological ...
Natalia Martínez-González   +3 more
doaj   +1 more source

Treatment Model in Children with Speech Disorders and Its Therapeutic Efficiency

open access: yesInternational Archives of Otorhinolaryngology, 2014
Introduction Speech articulation disorders affect the intelligibility of speech. Studies on therapeutic models show the effectiveness of the communication treatment.
Luciana Barberena   +3 more
doaj   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Embedding public and patient involvement in childhood stuttering research: lessons learned from engaging children and families in Saudi Arabia

open access: yesResearch Involvement and Engagement
Background Public and Patient Involvement (PPI) is increasingly recognised as essential for ensuring health research is relevant, inclusive, and responsive to local contexts.
Alhanouf Yosef Alhazimi   +2 more
doaj   +1 more source

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