Results 91 to 100 of about 473,453 (298)

Unravelling social network usage patterns: A study based on unsupervised learning

open access: yesCyberpsychology: Journal of Psychosocial Research on Cyberpspace
We are facing a growing concern regarding the consequences of Problematic Social Network Use (PSNU). Therefore, the aim of the present study was to explore the profiles of social network (SN) users and contrast their differences across variables linked ...
Alfredo Zarco-Alpuente   +7 more
doaj   +1 more source

بررسي ساختار سازه ای واکه های زبان فارسی در دانش آموزان مبتلا به شکاف لب و کام در محدوده ی سنی 9-7 ساله

open access: yesمجله پژوهش در علوم توانبخشی, 2011
چكيده مقدمه:اهميت فركانس سازه اي به گونه اي است كه روابط ميان سه سازه اول از اجزاي اصلي تشخيص نوع واكه توسط فرد شنونده مي باشد. به علاوه كيفيت يك واكه به بسامد سازه هاي آن بستگي دارد، بنابراين كاربرد اصلي اندازه گيري بسامد سازه در توصيف خطاهاي واكه اي ...
Faranak Salehi   +4 more
doaj   +1 more source

Beneficial effects of pharmacological treatment in post-stroke dynamic aphasia: a behavioural and neuroimaging study [PDF]

open access: yes, 2018
Introduction : Dynamic Aphasia (DA) is a rare form of language disorder characterized by reduced spontaneous speech with preservation of other language functions.
Beltrán-Corbellini, Álvaro   +8 more
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

The Impact of Dizziness on the Quality of Life of 235 Individuals who Completed Vestibular Testing in Brazil

open access: yesInternational Archives of Otorhinolaryngology, 2016
Introduction In Vestibular Testing (VT), caloric tests allow evaluation of unilateral weakness (UW) and directional preponderance (DP), where different criteria of normality are adopted in Brazil and worldwide.
Najlla Lopes de Oliveira Burle   +3 more
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Criteria for selecting children for speech therapy in the public schools [PDF]

open access: yes, 1961
Thesis (Ed.M.)--Boston ...
Driben, Margo, Rubin, Lillian B.
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

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