Results 41 to 50 of about 5,976,836 (291)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Syllable-rate-adjusted-modulation (SRAM) predicts clear and conversational speech intelligibility

Frontiers in Human Neuroscience
IntroductionObjectively predicting speech intelligibility is important in both telecommunication and human-machine interaction systems. The classic method relies on signal-to-noise ratios (SNR) to successfully predict speech intelligibility.
Ye Yang, Fan-Gang Zeng, Fan-Gang Zeng
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Lombard speech synthesis using transfer learning in a Tacotron text-to-speech system

, 2019
Currently, there is increasing interest to use sequence-to-sequence models in text-to-speech (TTS) synthesis with attention like that in Tacotron models.
Bajibabu Bollepalli, Paavo Alku, Bollepalli, Bajibabu, Alku, Paavo, Lauri Juvela, Juvela, Lauri   +5 more
core   +1 more source

Acoustic Optimization of Classroom Environments Using Oriented Strand Board Panels: Layout Strategy and Simulation Validation

Buildings
Classroom acoustic quality plays a crucial role in speech intelligibility and effective learning. However, many existing classrooms suffer from excessive reverberation and insufficient speech clarity.
Shuang Yan, Liutao Zhang, Zhenbo Liu, Haonan Wang   +3 more
doaj   +1 more source

A MATLAB toolbox for computation of Speech Transmission Index (STI)

2025 17th International Congress on Ultra Modern Telecommunications and Control Systems and Workshops (ICUMT)
The speech transmission index (STI) is a popular simple metric for the prediction of speech intelligibility when speech is passed through a transmission channel. Computation of STI from acoustic measurements is described in the IEC 60268-16:2020 standard.
Pavel Rajmic, Jiri Schimmel, Simon Cieslar   +2 more
openaire   +4 more sources

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

A Turbo-Coded Burst-by-Burst Adaptive Wide-Band Speech Transceiver

, 2000
Turbo-coded burst-by-burst adaptive orthogonal frequency division multiplex (AOFDM) wide-band speech transceivers are proposed. A constant throughput adaptive OFDM transceiver was designed and benchmarked against a time-variant rate scheme.
Münster, M., Keller, T., Hanzo, L.
core   +1 more source

Estimation of logatom intelligibility with the STI method for Polish speech transmitted via communication channels

Archives of Acoustics, 2004
An objective measure of the quality of speech communication channels was introduced and described by Steeneken-Houtgast. By calculating the Speech Transmission Index (STI), this method provides an estimate of logatom intelligibility for a ...
S. Brachmański
doaj