Results 91 to 100 of about 2,573,886 (339)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Speed bump detection on LiDAR point cloud for autonomous vehicles

open access: yesJournal of Electrical Systems and Information Technology
Speed bump detection is paramount for ensuring the safe and comfortable operation of autonomous vehicles while complying with traffic regulations. Detecting speed bumps well in advance enables timely brake application, ensuring a smooth travel experience
Bhaskar Anand, Rajalakshmi Pachamuthu
doaj   +1 more source

Rotor Dynamic Characteristics Supported by Multi-Pad Bump Foil Gas Bearings

open access: yesLubricants
Bump foil gas bearings (BFGBs) play an important role in high-speed turbomachinery. However, most studies on the dynamic characteristics of BFGBs focus on a one-pad structure composed of a bump foil and a top foil. This paper considers the multi-pad foil
Lei Zhao   +3 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Revolution-bump mapping with texture function adjustment according to the geometry of the revolved object

open access: yesJournal of Graphic Engineering and Design
Nowadays, 3D computer graphics are firmly anchored in our daily lives, extending across a multitude of distinct fields. Although each field follows its specific objectives, two major objectives are taken into consideration: realism and rendering speed ...
Anouar Ragragui   +5 more
doaj   +1 more source

Instabilities in the Envelopes and Winds of Very Massive Stars

open access: yes, 2014
The high luminosity of Very Massive Stars (VMS) means that radiative forces play an important, dynamical role both in the structure and stability of their stellar envelope, and in driving strong stellar-wind mass loss.
A. A. Belyanin   +53 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Rossby Wave Instability and Long-Term Evolution of Dead Zones in Protoplanetary Discs

open access: yes, 2015
The physical mechanism of angular momentum transport in poorly ionized regions of protoplanetary discs, the dead zones (DZs), is not understood. The presence of a DZ naturally leads to conditions susceptible to the Rossby wave instability (RWI), which ...
Lai, Dong   +2 more
core   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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