Results 91 to 100 of about 6,364 (304)

Influence of speed bumps on braking distance

IOP Conference Series: Materials Science and Engineering, 2019
Abstract This paper aims to dismiss the popular belief that speed bumps reduce the vehicle speeds or reduce the braking distance. In recent years, the implementation of speed bumps on public roads in Romania has increased. The correct understanding of the role of the speed bump has been misunderstood by the Romanian authorities who use ...
A Maftei, A I Dontu, L Gaiginschi, I Agape   +3 more
openaire   +1 more source

Marked Speed Bump/ Speed Breaker Dataset (India)

This dataset contains cropped marked speed bump/breaker images used in the paper, "Driver Assistance System for Marked Speed Breaker Detection".Total number of images is 969.
Nahar, S (via Mendeley Data)
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

The Best Location for Speed Bump Installation Using Experimental Design Methodology

Promet (Zagreb), 2013
Speed bumps, as traffic calming devices, have been extensively used to reduce traffic speed on local streets. This study represents a unique application of experimental design methodology where the effects of some controllable factors in determining the ...
Alireza Khademi, Nafiseh Ghorbani Renani, Maryam Mofarrahi, Alireza Rangraz Jeddi, Noordin Mohd Yusof   +4 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

The Effect of Rounding in Bump Foil Structure on the Dynamic Performance of Foil Journal Bearings

Tribology Online, 2019
The performance of air foil journal bearings is closely related to the stiffness of the bump foil. In this paper, the stiffness characteristics of bump foil having a rounding in the structure are investigated and compared with previous models.
Hongyang Hu, Ming Feng
doaj   +1 more source

Characterization of the Speed Bump Phenotype in Zebrafish

, 2019
iv, 36 p.In order for cells to grow and survive they must undergo the cell cycle A large-scale zebrafish mutagenesis produced the speed bump mutant; widely thought to be the result of a mutation in the wee1 gene The kinase Wee1 regulates entry into ...
Johnston, Emily
core  

Hubungan Peningkatan Kebisingan, Penurunan Kecepatan, dan Dimensi Tinggi Speed Bump di Permukiman (Studi Kasus Beberapa Speed Bumps di Surakarta) [PDF]

, 2016
ABSTRAK Faisal Kus Hermawan. 2015. Hubungan Peningkatan Kebisingan, Penurunan Kecepatan, dan Dimensi Tinggi Speed Bumps di Permukiman (Studi Kasus Beberapa Speed Bump di Surakarta). Skripsi. Program Studi Teknik Sipil. Fakultas Teknik.
HERMAWAN, FAISAL KUS
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source