Results 101 to 110 of about 2,573,886 (339)

Application of a compliant foil bearing for the thrust force estimation in the single stage radial blower

Open Engineering, 2015
The paper presents the application of a compliant foil bearing for estimation of the thrust force in a single stage radial blower under operational conditions. The bump foil of the thrust bearing behaves as a nonlinear spring. The knowledge of the spring
Łagodzinski Jakub, Miazga Kacper, Musiał Izabela   +2 more
doaj   +1 more source

The Dynamics and Afterglow Radiation of Gamma-Ray Bursts. I. Constant Density Medium

, 2009
Direct multi-dimensional numerical simulation is the most reliable approach for calculating the fluid dynamics and observational signatures of relativistic jets in gamma-ray bursts (GRBs). We present a two-dimensional relativistic hydrodynamic simulation
Andrew MacFadyen, Ayal, Barkov, Berger, Berger, Blandford, Bucciantini, Cannizzo, Chevalier, Chevalier, Cohen, Dai, Dai, Dalal, Frail, Frail, Frail, Fryxell, Granot, Granot, Granot, Granot, Granot, Grupe, Gruzinov, Gruzinov, Harrison, Harrison, Kumar, Levinson, Li, Livio, MacFadyen, Medvedev, Meszaros, Meszaros, Meszaros, Mignone, Morsony, Nakar, Nishikawa, Nousek, O'Brien, Paczynski, Panaitescu, Panaitescu, Panaitescu, Perna, Ramirez-Ruiz, Rhoads, Rhoads, Sari, Sari, Sari, Soderberg, Spitkovsky, Stanek, Synge, Uzdensky, Uzdensky, Wang, Waxman, Waxman, Weiqun Zhang, Wijers, Zeh, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang   +71 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Manual wheelchair downhill stability: an analysis of factors affecting tip probability

Journal of NeuroEngineering and Rehabilitation, 2018
Background For people who use manual wheelchairs, tips and falls can result in serious injuries including bone fractures, concussions, and traumatic brain injury.
Louise Thomas, Jaimie Borisoff, Carolyn J. Sparrey   +2 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Three-dimensional numerical simulation of a vortex ring impacting a bump

Theoretical and Applied Mechanics Letters, 2014
A vortex ring impinging on a three-dimensional bump is studied using large eddy simulation for a Reynolds number Re = 4 × 104 based on the initial translation speed and diameter of the vortex ring.
Heng Ren, Changyue Xu
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

The Best Location for Speed Bump Installation Using Experimental Design Methodology

Promet (Zagreb), 2013
Speed bumps, as traffic calming devices, have been extensively used to reduce traffic speed on local streets. This study represents a unique application of experimental design methodology where the effects of some controllable factors in determining the ...
Alireza Khademi, Nafiseh Ghorbani Renani, Maryam Mofarrahi, Alireza Rangraz Jeddi, Noordin Mohd Yusof   +4 more
doaj   +1 more source

On the role of magnetosonic solitons in perpendicular collisionless shock reformation

, 2017
The nature of the magnetic structure arising from ion specular reflection in shock compression studies is examined by means of 1d particle in cell simulations.
Fisch, Nathaniel J., Gueroult, Renaud, Oshawa, Yukiharu   +2 more
core   +3 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source