DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
RESEARCH ON FUZZY CONTROL SIMULATION OF CVT RATIO BASED ON ENGINE SPEED REGULATION CHARACTERISTICS
Jixie qiangdu, 2019 According to the load characteristics and speed regulation characteristics of the engine,the steady-state torque model is established and the optimum power and economy curves of engine are determined. Then the engine target speed is obtained by using the
GUO Wei, JIA GaoXiang, ZHANG Wu, CHEN Ya
doaj
Speed regulation of genetic cascades allows for evolvability in the body plan specification of insects. [PDF]
Proc Natl Acad Sci U S A, 2017 Zhu X +6 more
europepmc +1 more source
Determining a Reasonable Speed for Xinjiang’sTourism Development in the ‘14<sup>th</sup> Five-Year Plan’under the Green Concept: Analysis fromthe Perspective of Water Environment Regulation [PDF]
, 2021 Xiaoyuan Wu +3 more
openalex +1 more source
Control concepts for the alleviation of windshears and gusts [PDF]
Automatic control system design methods for gust and shear alleviation were studied. It is shown that automatic gust/shear alleviation systems can be quite effective if both throttle and elevator are used in harmony to produce the forces and moments ...
Govindaraj, K. S., Rynaski, E. G.
core +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Research on Traction Speed Regulation and Braking Device of Pipeline Intelligent Plugging Robot
工程科学与技术ObjectiveWith increasing pipeline mileage and service time, more pipelines are being damaged due to environmental corrosion and human factors. This damage results in interruptions in transport and leakage of oil and gas, which in turn causes economic ...
TANG Yang +3 more
doaj
Research of Full Range Speed-regulation System Based on Bivariate 6-pulse Wave AC-AC Converter
Gong-kuang zidonghua, 2010 The paper proposed a design scheme of full range speed-regulation system based on bivariate 6-pulse wave AC-AC converter. It analyzed control principle of bivariate 6-pulse wave AC-AC converter, introduced characteristics and design of main circuit and ...
JIA Ji-guang, DU Shao-tong
doaj
TMC4 localizes to multiple taste cell types in the mouse taste papillae
FEBS Open Bio, EarlyView.Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source