Results 121 to 130 of about 487,985 (362)

A microfluidic method for passive trapping of sperms in microstructures [PDF]

open access: yesarXiv, 2022
Sperm motility is a prerequisite for male fertility. Enhancing the concentration of motile sperms in assisted reproductive technologies - for human and animal reproduction - is typically achieved through aggressive methods such as centrifugation. Here we propose a passive technique for the amplification of motile sperm concentration, with no externally
arxiv  

Sperm‐Derived CircRNA‐1572 Regulates Embryogenesis and Zygotic Genome Activation by Targeting CCNB2 via Bta‐miR‐2478‐L‐2

open access: yesAdvanced Science, EarlyView.
Sperm‐derived circRNA‐1572 competitively binds to bta‐miR‐2478‐L‐2 through a “sponge” mechanism to regulate cyclin B2 (CCNB2) expression, thereby modulating the distribution of fibrous actin (F‐actin) in early pig embryos, ensuring proper chromosome segregation during mitosis, and facilitating normal embryo cleavage and zygotic genome activation.
Yanfang Wu   +10 more
wiley   +1 more source

Use of sperm DNA fragmentation testing and testicular sperm for intracytoplasmic sperm injection [PDF]

open access: yesTranslational Andrology and Urology, 2017
Dr. Ahmad, in his well-written commentary (1), shared his viewpoints about the utility of sperm DNA fragmentation (SDF) testing on each clinical scenario proposed in the practice recommendations by Agarwal et al . (2). He highlighted the pitfalls of relying on quantitative semen parameters in current practice and the need for a more reliable ...
Ashok Agarwal   +3 more
openaire   +3 more sources

REVIEW: Current Status of Extenders and Cryoprotectants on Fish Spermatozoa Cryopreservation [PDF]

open access: yes, 2005
An important component of many studies of cryopreservation of fish spermatozoa is the type of extenders and cryoprotectants. The suitability of extenders and cryoprotectants differs from one fish to another.
Z.A, Muchlisin
core  

Mitofusin 1 Drives Preimplantation Development by Enhancing Chromatin Incorporation of Histone H3.3

open access: yesAdvanced Science, EarlyView.
MFN1 exerts its function partially through histone H3.3 in early embryos. MFN1 colocalizes with PADI6, and its deficiency results in compromised cytoplasmic lattices and ribosomal subunits, leading to declined H3.3 protein level. This, in turn, hinders the incorporation of H3.3 into the embryonic genome, thereby causing failure of male pronucleus ...
Xiao‐yan Shi   +9 more
wiley   +1 more source

High-resolution 4D acquisition of freely swimming human sperm cells without staining [PDF]

open access: yesarXiv, 2020
We present a new acquisition method that enables high-resolution, fine-detail full reconstruction of the three-dimensional movement and structure of individual human sperm cells swimming freely. We achieve both retrieval of the three-dimensional refractive-index profile of the sperm head, revealing its fine internal organelles and time-varying ...
arxiv  

Paternal Obesity‐Induced H3K27me3 Elevation Leads to MANF‐Mediated Transgenerational Metabolic Dysfunction in Female Offspring

open access: yesAdvanced Science, EarlyView.
Paternal lifestyle and environmental exposures play a critical role in the offspring's health. The present study established a paternal obesity model and demonstrated that elevated H3K27me3 levels in sperm persist through the 8‐cell embryo stage. This epigenetic modification triggers transgenerational decrease of MANF, inducing ER stress and activating
Yajun Shi   +13 more
wiley   +1 more source

Systematic and Bibliometric Analysis of Magnetite Nanoparticles and Their Applications in (Biomedical) Research

open access: yesGlobal Challenges, Volume 7, Issue 1, January 2023., 2023
Bibliometric and systematic analysis shows research from 1990 to 2020 reveals the versatility of magnetite nanoparticles and their evolving usage in a number of fields. Initially focusing on the environmental and industrial applications, to the biomedical applications. However, recent research highlights their toxicity and potential detrimental effects
Charlotte L. Fleming   +3 more
wiley   +1 more source

Chromosome‐Level Genome Assembly of the Leafcutter Bee Megachile rotundata Reveals Its Ecological Adaptation and Pollination Biology

open access: yesAdvanced Science, EarlyView.
The genome of Megachile rotundata, an extensively managed solitary pollination bee species, has been sequenced, covering 280.68 Mb and predicting 10 701 genes. The study reveals significant expansions of the Toll gene family and their abundant expression in diapause prepupae, highlighting enhanced immune responses during diapause. This genome serves as
Rangjun Shi   +8 more
wiley   +1 more source

A pathogenic variant in the uncharacterized RNF212B gene results in severe aneuploidy male infertility and repeated IVF failure

open access: yesHGG Advances, 2023
Summary: Quantitative and qualitative spermatogenic impairments are major causes of men’s infertility. Although in vitro fertilization (IVF) is effective, some couples persistently fail to conceive.
Moran Gershoni   +10 more
doaj  

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