Results 121 to 130 of about 552,185 (343)
DNA demethylation by ROS1a in rice vegetative cells promotes methylation in sperm. [PDF]
, 2019 Epigenetic reprogramming is required for proper regulation of gene expression in eukaryotic organisms. In Arabidopsis, active DNA demethylation is crucial for seed viability, pollen function, and successful reproduction. The DEMETER (DME) DNA glycosylase
Fischer, Robert L +6 more
core +2 more sources
Advanced Science, EarlyView.This study investigates a highly multivalent mAb platform fusing Laminin‐511 heterotrimerization domains with Fabs and IgG1‐Fc as a non‐hormonal contraceptive. The most potent molecule ‘LamH10’, possessing 10 Fabs, rapidly achieved >99% reduction in progressively motile sperm at just 33µg per dose in sheep, making the laminin‐IgG hybrid platform the ...
Alison Schaefer +8 more
wiley +1 more source
Cryptic female choice favours sperm from major histocompatibility complex-dissimilar males [PDF]
, 2013 Cryptic female choice may enable polyandrous females to avoid inbreeding or bias offspring variability at key loci after mating. However, the role of these genetic benefits in cryptic female choice remains poorly understood. Female red junglefowl, Gallus
Alcaide M +8 more
core +1 more source
Advanced Science, EarlyView.The limited understanding of IGFR pathway activation hinders its clinical application in HCC. Here, IGFRIL is identified as a novel non‐coding activator of the IGF1R, which recruits PTBP1 to destabilize IGFBP3 mRNA and activates IGF1R, and proposes IGFRIL as a novel actionable target for HCC patients.
Jing Zhang +28 more
wiley +1 more source
Low-Cost QCM Sensor System for Screening Semen Samples [PDF]
, 2010 Artificial insemination is a well-established part of modern agricultural practice. A viable semen sample is judged by the total number of spermatozoa (sperm) in the sample and the motility of the sperm.
Atherton, Shaun +6 more
core +2 more sources
Stem Cell Reports, 2014 Generation of functional spermatids from azoospermia patients is of unusual significance in the treatment of male infertility. Here, we report an efficient approach to obtain human functional spermatids from cryptorchid patients.
Shi Yang +10 more
doaj +1 more source
, 2015 Banka sperme (ili kriobanka) je način/mogućnost pohrane sperme čovjeka. Spermu potom koriste žene koje žele postići trudnoću i materinstvo. Dva su glavna razloga zašto se muškarci odluče na pohranu (donaciju) sperme: 1) da bi osigurali reproduktivnu sposobnost kada su suočeni s bolešću koja bi mogla biti smrtonosna ili čije bi liječenje moglo ...
openaire +1 more source
Advanced Science, EarlyView.The quantitative proteomic and phosphoproteomic profiling reveals dynamic phosphorylation regulation of sperm morphogenesis. Kinase‐substrate phosphorylation network and phosphorylation module analysis, followed by in vivo knockdown and knockout analysis, identify TTBK2 and CSNK1G1 as key regulators of morphogenesis, including head, flagellar, and ...
Tianyu Zhu +25 more
wiley +1 more source
In-vitro application of pentoxifylline preserved ultrastructure of spermatozoa after vitrification in asthenozoospermic patients [PDF]
, 2017 PURPOSE: To evaluate the effect of in vitro application of pentoxifylline (PX) on sperm parameters and ultrastructure after vitrification in asthenozoospermic patients. MATERIALS AND METHODS: A total of 30 asthenozoospermic semen samples (aged 25-45
Khalili, Ma +7 more
core
Methylation Status of Imprinted Genes and Repetitive Elements in Sperm DNA from Infertile Males [PDF]
, 2011 Stochastic, environmentally and/or genetically induced disturbances in the genome-wide epigenetic reprogramming processes during male germ-cell development may contribute to male infertility.
El Hajj, N. +7 more
core +1 more source