Results 181 to 190 of about 726,910 (390)

Differences in Dynamics of Specific Antinuclear Antibodies and Their Susceptibility to B Cell–Targeting Treatment in Patients With Systemic Lupus Erythematosus

open access: yesArthritis &Rheumatology, EarlyView.
Objective The presence of antinuclear antibodies (ANAs) is characteristic for systemic lupus erythematosus (SLE). Antibody dynamics over time are thought to reflect the cellular source of ANAs and their therapeutic targetability. Anti–double‐stranded DNA (anti‐dsDNA) is the most prevalent and well‐studied of all ANAs, and fluctuations in anti‐dsDNA ...
Hugo J. van Dooren   +16 more
wiley   +1 more source

Pregnancy outcomes in women with systemic sclerosis before and/or after diagnosis, and by parity ‐ A Swedish population‐based cohort study

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To assess risks of adverse pregnancy outcomes (APO) in a contemporary cohort of women with systemic sclerosis (SSc) in relation to the timing of SSc diagnosis and by parity. Methods From the nationwide Swedish Medical Birth Register, we assembled pregnancies with births in women with SSc and in comparator women from the general population ...
Weng Ian Che   +5 more
wiley   +1 more source

Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder

open access: yesScience, 2016
Qi Chen   +13 more
semanticscholar   +1 more source

TRPV4 is the temperature-sensitive ion channel of human sperm. [PDF]

open access: yes, 2018
Ion channels control the ability of human sperm to fertilize the egg by triggering hyperactivated motility, which is regulated by membrane potential, intracellular pH, and cytosolic calcium.
Lishko, Polina V   +2 more
core   +2 more sources

Age, Race, and Ethnicity of Maternal Grandparents in Autism Spectrum Disorder, a California Multigenerational Study

open access: yesAutism Research, EarlyView.
ABSTRACT We investigated associations between maternal grandparents' age and autism spectrum disorders (ASD) in grandchildren, exploring differences by race/ethnicity. In a multigenerational California birth cohort study including 1,743,998 and 1,630,722 mother–child pairs (with 27,975 and 25,816 ASD cases, respectively), we examined ASD risk by ...
Ting Chow   +5 more
wiley   +1 more source

The annulus: composition, role and importance in sperm flagellum biogenesis and male fertility

open access: yesBasic and Clinical Andrology
The annulus is an electron-dense ring structure that surrounds the axoneme and compartmentalizes the sperm flagellum into two parts: the midpiece and the principal piece.
Marjorie Whitfield
doaj   +1 more source

Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals

open access: yesScience, 2016
Upasna Sharma   +19 more
semanticscholar   +1 more source

The ductal network in the human testis and epididymis: What belongs to which?

open access: yesClinical Anatomy, EarlyView.
Abstract The testes and epididymis are traversed by a system of tubules in which sperm cells are generated, matured, nourished, and transported. Among these are the efferent ductules, which connect the rete testis to the duct of the epididymis. In the Terminologia Anatomica (TA), the efferent ductules are assigned to the testicles, while numerous ...
Andreas Gocht   +3 more
wiley   +1 more source

Fertility preservation in male adolescents with cancer (2011–2020): A retrospective study in China

open access: yesCancer Medicine
Background According to the studies, more than 80% of pediatric patients with cancer can achieve a survival rate greater than 5 years; however, long‐term chemotherapy and/or radiation therapy may seriously affect their reproductive ability.
Shasha Liu   +26 more
doaj   +1 more source

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