Results 181 to 190 of about 487,985 (362)

DNA‐binding properties of non‐intercalating water‐soluble organometallic Ir(III) luminophores

open access: yesChemistry – A European Journal, Accepted Article.
A series of Ir(III) complexes, [Ir(C^N)2(en)]+ (where C^N = 2‐phenyl‐benzo[d]thiazolyl cyclometalating ligand; en = ethylene diamine), are reported with structural variation via a substituent (H, Me, OMe, Cl, OCF3) at the coordinated phenyl ring.
Ibrahim Alkhaibari   +4 more
wiley   +1 more source

Predicting DNA fragmentation: A non-destructive analogue to chemical assays using machine learning [PDF]

open access: yesarXiv
Globally, infertility rates are increasing, with 2.5\% of all births being assisted by in vitro fertilisation (IVF) in 2022. Male infertility is the cause for approximately half of these cases. The quality of sperm DNA has substantial impact on the success of IVF.
arxiv  

Enzyme‐Catalysed Formation of Hydrocarbon Scaffolds from Geranylgeranyl Diphosphate Analogs with Shifted Double Bonds

open access: yesChemistry – A European Journal, EarlyView.
Four new geranylgeranyl diphosphate analogs with shifted double bonds were synthesized and together with the known analog iso‐GGPP I converted with 14 diterpene synthases. While two substrate analogs were not accepted by the enzymes, the other three analogs yielded compounds with skeletons that are not observed in nature.
Heng Li   +2 more
wiley   +1 more source

Single‐cell RNA‐sequencing of retrieved human oocytes and eggs in clinical practice and for human ovarian cell atlasing

open access: yesMolecular Reproduction and Development, Volume 89, Issue 12, Page 597-607, December 2022., 2022
Abstract With the advancement of single‐cell separation techniques and high‐throughput sequencing platforms, single‐cell RNA‐sequencing (scRNA‐seq) has emerged as a vital technology for understanding tissue and organ systems at cellular resolution. Through transcriptional analysis, it is possible to characterize unique or rare cell types, interpret ...
Jordan H. Machlin, Ariella Shikanov
wiley   +1 more source

Fertility preservation in male adolescents with cancer (2011–2020): A retrospective study in China

open access: yesCancer Medicine
Background According to the studies, more than 80% of pediatric patients with cancer can achieve a survival rate greater than 5 years; however, long‐term chemotherapy and/or radiation therapy may seriously affect their reproductive ability.
Shasha Liu   +26 more
doaj   +1 more source

TRPV4 is the temperature-sensitive ion channel of human sperm. [PDF]

open access: yes, 2018
Ion channels control the ability of human sperm to fertilize the egg by triggering hyperactivated motility, which is regulated by membrane potential, intracellular pH, and cytosolic calcium.
Lishko, Polina V   +2 more
core   +2 more sources

Myosin VI Is Associated With the Endoplasmic Reticulum in Regions of Sertoli Cells Containing Tubulobulbar Complexes

open access: yesCytoskeleton, EarlyView.
ABSTRACT Myosin VI has been reported by others to localize in association with various regions of apical tubulobulbar complexes (TBCs) at sites of attachment between Sertoli cells and late spermatids in the mouse. Tubulobulbar complexes internalize “intact” intercellular junctions during sperm release and during spermatocyte translocation through the ...
Samuel Tretjakov   +2 more
wiley   +1 more source

Structures and functions of cilia during vertebrate embryo development

open access: yesMolecular Reproduction and Development, Volume 89, Issue 12, Page 579-596, December 2022., 2022
Abstract Cilia are hair‐like structures that project from the surface of cells. In vertebrates, most cells have an immotile primary cilium that mediates cell signaling, and some specialized cells assemble one or multiple cilia that are motile and beat synchronously to move fluids in one direction.
Jeffrey D. Amack
wiley   +1 more source

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