Results 121 to 130 of about 42,226 (251)

Sperm Mitochondrial DNA Copy Number and Nuclear DNA Methylation Across Clinical and Non‐Clinical Preconception Cohorts

Andrology, EarlyView.
ABSTRACT Background Sperm mitochondrial DNA copy number is an emerging marker of male fertility, with elevated mtDNAcn associated with poor semen quality across various populations. Sperm DNA methylation has also been previously demonstrated to be negatively correlated with semen parameters in IVF cohorts.
Savni Sawant, Karolina Nowak, Amanda L. Paskavitz, Emily Houle, Ricardo P. Bertolla, Lidia Minguez‐Alarcon, Russ Hauser, J. Richard Pilsner   +7 more
wiley   +1 more source

Role of ANO1‐Expressing PDGFRα+ Smooth Muscle Cells in Generating Spontaneous Phasic Contractions of the Rodent Epididymis

Andrology, EarlyView.
ABSTRACT Background Spontaneous phasic contractions (SPCs) in the epididymal duct play an important role in transport and maturation of sperm. In proximal cauda of the rat epididymis, platelet‐derived growth factor receptor α (PDGFRα)‐positive smooth muscle cells (SMCs) generate ANO1 Ca2+‐activated chloride channels (CaCCs)‐dependent spontaneous ...
Wataru Kudo, Hiromichi Takano, Toshiya Izuchi, Retsu Mitsui, Kyoko Miwa‐Nishimura, Hikaru Hashitani   +5 more
wiley   +1 more source

A novel frameshift variant in <i>TTC29</i> associated with total asthenozoospermia and male infertility. [PDF]

Front Cell Dev Biol
Li L, Wan F, Feng K, Qu X, Xia Y, Dong J, Liu Y, Zhao Y, Zhu G, Yin B, Guo H.   +10 more
europepmc   +1 more source

Obesity Is an Independent Risk Factor for Oligozoospermia, With Co‐Existing Hyperglycemia Exacerbating Risks of Asthenozoospermia and Elevated Sperm DNA Fragmentation

Andrology, EarlyView.
ABSTRACT Background Metabolic health plays a critical role in maintaining male fertility and may influence offspring health. Therefore, it is necessary to incorporate metabolic indicators into the clinical assessment of male fertility. However, the relationships between different metabolic abnormalities and semen quality remain incompletely understood.
Rubing Hu, Haijiao Zou, Qiaodan Li, Weihong Fan, Jian Xu   +4 more
wiley   +1 more source

A Novel Homozygous Mutation in <i>ARL2BP</i> Causes Multiple Morphological Abnormalities of the Flagella and Primary Ciliary Dyskinesia. [PDF]

Hum Mutat
Li M, Tao W, Ji Q, Yan D, Zhang C, Zhang Q, Jiang P, Qiu J, Wen J, Xu B, Bai S, Jiang X.   +11 more
europepmc   +1 more source

Occupational Physical Activity Is Negatively Associated With Semen Quality

Andrology, EarlyView.
ABSTRACT Background Lifestyle factors have been associated with semen quality and have been implicated in the reported global decline in semen parameters. Moderate physical activity has been linked to improved semen quality; however, the association between occupational physical activity and semen quality is limited.
Michal Efrat, Sharon Barak, Anat Stein, Haim Pinkas, Ron Unger, Ruth Birk   +5 more
wiley   +1 more source

Before Orchiectomy: Gonadal Function in Testicular Germ Cell Tumors-A Narrative Review. [PDF]

J Clin Med
Kaltsas A, Giannakodimos I, Kratiras Z, Sofikitis N, Chrisofos M.   +4 more
europepmc   +1 more source

Children Born Using Ejaculated Sperm From Men With Klinefelter Syndrome. Is Sperm Production Associated With Testicular Volume?

Andrology, EarlyView.
ABSTRACT Background A large number of children have been born using testicular sperm from men with Klinefelter syndrome (KS), whereas reports of children conceived using ejaculated sperm are rare. Objective To review all published cases of children conceived using ejaculated sperm from men with KS, assess their health and karyotype, and evaluate ...
Jens Fedder, Freja Sørensen
wiley   +1 more source

Integration of Proteomics and Phenomics to Reveal Molecular Differences in High and Low Semen Quality in Donkeys. [PDF]

Reprod Domest Anim
Ma C, Reyimujiang Y, Guo Y, Chang S, Wu H, Pang Y, YuanWeiLu C, Yang F, Zhang Y, Li N, Liu Q, Zeng S.   +11 more
europepmc   +1 more source

Seminal Biomarkers and Sperm Proteomic Signatures Differentiate Acute and Chronic Male Accessory Gland Inflammation

Andrology, EarlyView.
ABSTRACT Background Male accessory gland inflammation (MAGI) comprises a heterogeneous group of inflammatory conditions that may differentially affect the seminal microenvironment and sperm function. However, whether transrectal ultrasound (TRUS)‐defined MAGI phenotypes correspond to distinct biological profiles remains insufficiently characterized ...
Emanuela Teveroni, Fiorella Di Nicuolo, Giorgia Mazzuccato, Alessandro Oliva, Emanuele Pierpaolo Vodola, Francesca Mancini, Carla Di Nardo, Edoardo Vergani, Michela Cicchinelli, Federica Iavarone, Cassandra Serantoni, Giuseppe Maulucci, Alessia Riente, Alfredo Pontecorvi, Andrea Urbani, Domenico Milardi, Silvia Baroni   +16 more
wiley   +1 more source