Results 161 to 170 of about 42,226 (251)

GSK3α‐mediated regulation of the RNA demethylase fat mass and obesity‐associated protein (FTO) during murine spermatogenesis

The FEBS Journal, EarlyView.
FTO regulates mRNA stability and translational efficiency through its m6A‐demethylation activity. GSK3 functions as an upstream regulator of FTO, leading to its inhibition via phosphorylation. In male germ cells, FTO activity is kept in check by GSK3α.
Neha Choudhari, Budheswar Dehury, Rounak Roy, Radhakrishnan Periyasamy, Indrashis Bhattacharya, Mahesh Sahare, Srinivasan Vijayraghavan, Souvik Dey   +7 more
wiley   +1 more source

Exploratory seminal plasma metabolomics and independent HPLC-UV evaluation in men with impaired semen quality. [PDF]

Front Endocrinol (Lausanne)
Xu J, Guo L, Xiong L, Li J, Wu P, Ma Y, Yang J, Du Y.   +7 more
europepmc   +1 more source

Italian Patients Journey for Gene Therapy in Haemophilia A

Haemophilia, EarlyView.
ABSTRACT Introduction Gene therapy (GT) provides sustained FVIII levels without repeated infusions in Hemophilia A (HA) patients thus overcoming a major limitation of replacement therapy. However, issues remain e.g., patient selection criteria, duration and variability of transgene expression, quality of life and long‐term safety.
Giovanni Di Minno, Gaia Spadarella, Alessandra Borchiellini, Anna Borrelli, Andrea Buzzi, Giancarlo Castaman, Michele Cecchi, Raimondo De Cristofaro, Vincenzo La Mura, Angelo Lupi, Giuseppe Malcangi, Maria Elisa Mancuso, Maria Francesca Mansueto, Cristina Santoro, Rita Carlotta Santoro, Luigi Piero Solimeno, Annarita Tagliaferri, Ezio Zanon, Isabella Garagiola, Flora Peyvandi   +19 more
wiley   +1 more source

Comparative Evaluation of Staining Techniques in Thawed Cryopreserved Dog Semen. [PDF]

Vet Sci
Klumb IS, Wehrend A, Farshad A.
europepmc   +1 more source

Climate change impacts on fish in the Baltic Sea

Journal of Fish Biology, EarlyView.
Abstract The Baltic Sea is a marginal sea with strong abiotic gradients harbouring fish of both marine and freshwater origin. Here we review the empirical evidence for how changes in climate variables have impacted different fish and fish communities in the Baltic Sea.
Örjan Östman, Meri Kallasvuo, Sanna Kuningas, Antti Lappalainen, Noora Mustamäki, Rahmat Naddafi, Lauri Saks, Jens Olsson   +7 more
wiley   +1 more source

Biallelic Variants in ATP1A4 Are Associated with Oligoasthenoteratozoospermia and Male Infertility. [PDF]

Clin Genet
Zheng Y, Zhang Y, Ren K, Jiang C, Yang Y, Tian Y, Ouyang D, Wang X, Shen Y.   +8 more
europepmc   +1 more source

Role of the tomato MARS1/ROUGH gene encoding a LYSINE‐SPECIFIC HISTONE DEMETHYLASE 1 in adventitious root and fruit skin formation

Journal of Integrative Plant Biology, EarlyView.
The tomato mars1/rough mutant displays enhanced root regeneration and rough fruits due to ectopic cell proliferation. The causal gene encodes a lysine‐specific histone demethylase that normally maintains gene silencing. Its loss alters histone methylation, upregulating several genes, including those B‐type cyclins involved in tissue‐specific cellular ...
Eduardo Larriba, Cécile Bres, Aurora Alaguero‐Cordovilla, Riyazuddin Riyazuddin, Qingyi Wang, Johann Petit, Jean‐Philippe Mauxion, Lara Caballero, David Latrasse, Bénédicte Bakan, Rim Brik‐Chaouche, David Esteve‐Bruna, Moussa Benhamed, Christophe Rothan, José Manuel Pérez‐Pérez   +14 more
wiley   +1 more source

Summarizing the Experiences of Individuals Who Have Obesity or Larger Bodies Seeking Fertility Care: A Scoping Review

Obesity Reviews, EarlyView.
ABSTRACT Females who have larger bodies or obesity may be at an increased risk for experiencing infertility. Problematically, both weight or body size and infertility are stigmatized, harming quality of care. We conducted a scoping review to understand the lived experiences of patients who may be subjected to intersecting stigmas of weight and ...
Brooke J. Hebert, Hanna Randhawa, Virginie Blanchette, Kristi B. Adamo, Angela Alberga, Jean‐Patrice Baillargeon, Marilou Côté, Julia Craig, Ariadne Daniel, Liz Dennett, Nicola Heslehurst, Sarah Nutter, Ian Patton, Helena Piccinini‐Vallis, Ximena Ramos Salas, Katie Wadden, Taniya S. Nagpal   +16 more
wiley   +1 more source

Effect of semen collection timing on physiological responses and sperm functional parameters in Thai native bulls under tropical heat stress. [PDF]

Vet Anim Sci
Chankitisakul V, Boonkum W, Loetjettanarom T, Saiyamanon H, Buathalad K, Koedkanmark T, Authaida S, Phutthachalee S, Sutthikrai S, Anakkul N, Panyaboriban S.   +10 more
europepmc   +1 more source

New Considerations on Meiosis, Affinity and Genomic Constitution in Aneuploids and Interploid Hybrids of Urochloa P. Beauv. (Brachiaria)

Plant Breeding, EarlyView.
ABSTRACT The combination of polyploidy, apomixis and the formation of aneuploid and interploid hybrids makes the genus Urochloa an interesting system for investigating meiotic stability and genome behaviour in grasses. In this study, routine meiotic analysis and genomic in situ hybridization (GISH) were used to (i) evaluate meiosis in three hybrids of ...
Isabella Campos Moraes, Pedro Henrique Mendes Carvalho, Fausto Souza Sobrinho, Vânia Helena Techio   +3 more
wiley   +1 more source