Results 191 to 200 of about 5,887,583 (287)

Gonadotropin therapy in idiopathic hypogonadal non-obstructive azoospermia (APHRODITE Groups 3-4): a multicenter randomized controlled trial. [PDF]

Front Reprod Health
Chandra V, Esteves SC, Sanagoudar S.
europepmc   +1 more source

Long Noncoding RNA PCALRx Interacts with Pyruvate Carboxylase to Drive Multi‐Organ Developmental Toxicity in Zebrafish Embryos Exposed to Amoxicillin

Advanced Science, Volume 13, Issue 60, 28 October 2026.
Embryonic amoxicillin exposure disrupts multi‐organ development in zebrafish larvae through a lncRNA–metabolic enzyme regulatory axis. PCALRx associates with pyruvate carboxylase, promotes PC protein ubiquitination, and impairs mitochondrial energy metabolism, while vitamin B1 partially restores PC‐centered metabolic function and developmental outcomes.
Yixue Yao, Ping Jiang, Xinli Zhou, Mengying Yin, Qiong Luo, Hui Wang   +5 more
wiley   +1 more source

Non-Coding RNA Biomarkers in Male Infertility: From Discovery to Clinical Actionability-A Narrative Review. [PDF]

Genes (Basel)
Kaltsas A, Markou E, Zachariou A, Dimitriadis F, Sofikitis N.   +4 more
europepmc   +1 more source

RNA Promotes Synapsin Condensates That Organize Synaptic Vesicles in Live Neurons and Enable Localized Translation in Reconstituted System

Advanced Science, Volume 13, Issue 60, 28 October 2026.
Condensates at synapses organize synaptic vesicles (SVs) and are crucial for efficient neurotransmitter release, yet how RNA contributes to this mesoscale architecture remains poorly understood. Here we uncover that RNA modulates synapsin–driven condensates.
Branislava Rankovic, Zachary M. Geisterfer, Akshita Chhabra, Vladimir M. Jovanovic, Ian Seim, Christian Hoffmann, Antonela Condric, Gerard Aguilar Pérez, Rinse de Boer, Lars T. Hofstede, Jingao Sun, Kiara Freitag, Katja Nowick, Marina Jendrach, Frank L. Heppner, Vladimir Despic, Michaela Müller‐McNicoll, Stephan Sigrist, Geert van den Bogaart, Sofiia Reshetniak, Amy S. Gladfelter, Dragomir Milovanovic   +21 more
wiley   +1 more source

Biological and clinical factors predicting sperm retrieval success in men with non-obstructive azoospermia. [PDF]

Reprod Fertil
Ozturk S.
europepmc   +1 more source

Micro/Nanoscale Acoustic Manipulation: From Particle Control to Autonomous Microswimmers

Advanced Science, Volume 13, Issue 55, 5 October 2026.
This conceptual framework illustrates acoustic technology as a multifunctional platform enabling passive particle manipulation across scales and autonomous propulsion of microswimmers. ABSTRACT Acoustic manipulation and propulsion technologies have emerged as powerful platforms for micro/nanoscale control, enabled by their non‐contact operation, label ...
Jiahui Chu, Lemin Zhang, Xu Wang, Wenzong Li, Yahua Liu   +4 more
wiley   +1 more source

Ciliary Membrane Lipid Homeostasis in Health and Disease

Advanced Science, Volume 13, Issue 58, 19 October 2026.
This review systematically delineates the distinct lipid landscapes of ciliary membranes, including the spatial organization of phosphoinositides, cholesterol, and sphingolipids. It elucidates how these lipids orchestrate ciliogenesis, signal transduction, and membrane dynamics in cilia beating, and highlights how their dysregulation drives ...
Zhenzhou Huang, Yuan‐yuan Liu, Hanqi Sun, Peiwei Liu   +3 more
wiley   +1 more source

Safe and Stable Germline Transmission of MSTN Mutations in Cattle

Animal Genetics, Volume 57, Issue 5, October 2026.
ABSTRACT With the global population expected to reach 10 billion by 2050, sustainable livestock production is critical. Gene editing of the myostatin (MSTN) gene represents a promising strategy to enhance muscle growth in cattle. In this study, MSTN‐mutated founder (F0) cows were used to generate F1 offspring via ovum pick‐up, in vitro fertilization ...
Gyeong‐Min Gim, Bae Young Choi, Jeongbin Yi, Kyeong‐Hyeon Eom, Soo‐Young Yum, Dae‐Jin Jung, Do‐Yoon Kim, Bokyoung Yang, Jong‐Seo Kim, Donghwan Shim, Goo Jang   +10 more
wiley   +1 more source

Microfluidic sperm separation for intracytoplasmic sperm injection yields similar blastocyst rates compared with density gradient, however, may be of benefit for male factor infertility: a randomized sibling oocyte study. [PDF]

F S Rep
Fritz R, Arnott A, Tozour J, Sung L, Saketos M, Kuokkanen S, Goudas V, Rajan A.   +7 more
europepmc   +1 more source

Genome‐Wide Characterization of Heterozygosity‐Rich Regions in Kazakh Native Sheep Breeds

Animal Genetics, Volume 57, Issue 5, October 2026.
ABSTRACT Heterozygosity‐rich regions (HRR) are genomic segments characterized by high heterozygosity that may arise from admixture, introgression, or balancing selection and may harbor loci associated with adaptation and fitness‐related traits. This study aimed to characterize HRR patterns in five Kazakh sheep breeds using a publicly available ...
Sholpan Bakhtybekkyzy, Zarina Orazymbetova, Aizhan Mussayeva, Aidana Bekitayeva, Ajoy Mandal, Hasan Baneh   +5 more
wiley   +1 more source