Results 51 to 60 of about 157,835 (298)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Live Births Following Zona Pellucida–Binding Sperm Selection in Recurrent Implantation Failure: Two Case Reports

Fertility & Reproduction
Recurrent implantation failure (RIF) poses a significant challenge in assisted reproductive technologies (ART). Intracytoplasmic sperm injection (ICSI), while effective for male factor infertility, bypasses natural sperm selection, potentially reducing ...
Mahin Izadi, Serajoddin Vahidi Mehrjardi, Mohammad Ali Khalili, Mohammad Ebrahim Rezvani, Behrouz Aflatoonian   +4 more
doaj   +1 more source

Is sperm morphology functionally related to sperm swimming ability? A case study in a wild passerine bird with male hierarchies

BMC Evolutionary Biology, 2018
Background Sexual selection continues after copulation via either sperm competition or cryptic female choice, and favors sperm traits that maximize sperm competitiveness.
Alfonso Rojas Mora, Magali Meniri, Sabrina Ciprietti, Fabrice Helfenstein   +3 more
doaj   +1 more source

Polyandrous females avoid costs of inbreeding [PDF]

, 2002
Why do females typically mate with more than one male? Female mating patterns have broad implications for sexual selection, speciation and conflicts of interest between the sexes, and yet they are poorly understood. Matings inevitably have costs, and for
A Keil, DJ Howard, G Arnqvist, GA Parker, HA Qayyum, JA Zeh, JA Zeh, LW Simmons, LW Simmons, LW Simmons, LW Simmons, LW Simmons, LW Simmons, M Andersson, M Daly, M Olsson, M Olsson, M Olsson, MD Jennions, MW Lorenz, Nina Wedell, NW Thornhill, P Stockley, SD Newcomer, T Madsen, T Tregenza, T Tregenza, T Tregenza, TA Markow, TA Markow, Tom Tregenza, WG Eberhard   +31 more
core   +1 more source

A Surface‐engineered Microfluidic Device for Antibody‐Mediated Negative Selection of High‐Quality Sperm for Assisted Reproduction

Advanced Functional Materials, EarlyView.
This study reports a microfluidic device with a functionalized surface utilizing a polyoxazoline coating and covalently immobilized gold nanoparticles and anti‐phosphatidylserine antibody. The device efficiently eliminates pre‐apoptotic and apoptotic spermatozoa and yields sperm with substantially improved quality and low DNA damage, offering a simple ...
Soraya Rasi Ghaemi, David J. Sharkey, Nicole O. McPherson, Markos Negash Alemie, Krasimir Vasilev, Sarah A. Robertson   +5 more
wiley   +1 more source

Efficiency of Sperm Gradient Processing and HA-binding Test for the Selection of Sperm with Normal Protamine, Intact DNA and Normal Morphology [PDF]

Cell Journal, 2008
Objective: The aim of this study was to examine the efficiency of HA-binding test and sperm gradient processing method for the selection of sperm with normal protamine,intact DNA and normal morphology.Materials and Methods: The study was conducted on 29 ...
MT. Taghadosi, M. Tavalaee, SH. Razavi, M. Mardani, MH. Nasr Esfahani   +4 more
doaj  

Sperm Adhesion Molecule 1 (SPAM1) Distribution in Selected Human Sperm by Hyaluronic Acid Test

Biomedicines, 2022
The failures of binding to the oocyte zona pellucida are commonly attributed to defects in the sperm recognition, adhesion, and fusion molecules. SPAM1 (sperm adhesion molecule 1) is a hyaluronidase implicated in the dispersion of the cumulus-oocyte ...
María José Gómez-Torres, Paula Sáez-Espinosa, Paula Manzano-Santiago, Laura Robles-Gómez, Natalia Huerta-Retamal, Jon Aizpurua   +5 more
doaj   +1 more source

Nanodiamond Quantum Sensors for Probing Free Radical Biology

Advanced Functional Materials, EarlyView.
Free radicals play key roles in cellular signaling and disease but remain difficult to measure in living systems. Nanodiamonds (NDs) with nitrogen‐vacancy (NV) centers enable quantum sensing of local magnetic noise via T₁ relaxometry, providing nondestructive radical detection in living cells.
Qi Lu, Yingke Wu, Tanja Weil
wiley   +1 more source

Kinematic and spermatic recovery after selection by centrifugation in colloid solutions of ovine cryopreserved semen

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Frozen and thawed ovine semen undergo morphological and functional changes that prevent or decrease the efficiency of fertilization. Sperm selection methods seek to improve the quality and viability of the fertilizing materials.
T.G. Bergstein, L.C. Bicudo, L. Rodello, R.R. Weiss, S.D. Bicudo   +4 more
doaj   +1 more source

Practical Applications of Sperm Selection Techniques as a Tool for Improving Reproductive Efficiency

Veterinary Medicine International, 2011
Modern biotechnologies are used extensively in the animal breeding industry today. Therefore, it is essential that sperm handling procedures do not modulate the normal physiological mechanisms occurring in the female reproductive tract.
J. M. Morrell, H. Rodriguez-Martinez
doaj   +1 more source