Results 41 to 50 of about 157,835 (298)

Assessment of the effectiveness of methods for the selection of sperm with increased DNA fragmentation in ART cycles [PDF]

BIO Web of Conferences
Sperm DNA stability is significant in male infertility and favorable reproductive outcomes. Increased DNA fragmentation in spermatozoa can negatively affect the fertilization potential and the kinetics of embryo development.
Leontyeva Eugene, Kim Alena, Zastavskiy Ivan, Yakhyarova Mukhabbat, Polumiskov Vadim   +4 more
doaj   +1 more source

Assessing risks of invasion through gamete performance: farm Atlantic salmon sperm and eggs show equivalence in function, fertility, compatibility and competitiveness to wild Atlantic salmon [PDF]

, 2014
Adaptations at the gamete level (a) evolve quickly, (b) appear sensitive to inbreeding and outbreeding and (c) have important influences on potential to reproduce.
Einum, Sigurd, Fleming, Ian A., Gage, Matthew J.G., Holt, William V., Yeates, Sarah E.   +4 more
core   +1 more source

A biomimetic sperm selection device for routine sperm selection

Reproductive BioMedicine Online
Can a biomimetic microfluidic sperm sorter isolate motile sperm while minimizing DNA damage in comparison with density gradient centrifugation (DGC)?This was a two-phase study of 61 men, consisting of a proof-of-concept study with 21 donated semen samples in a university research laboratory, followed by a diagnostic andrology study with 40 consenting ...
Steven A, Vasilescu, Dale M, Goss, Kathryn H, Gurner, Rebecca L, Kelley, Maria, Mazi, Fabrice K, De Bond, Jennifer, Lorimer, Fabrizzio, Horta, Farin Y, Parast, David K, Gardner, Reza, Nosrati, Majid E, Warkiani   +11 more
openaire   +2 more sources

Experimental evolution of sperm competitiveness in a mammal

BMC Evolutionary Biology, 2011
Background When females mate with multiple partners, sperm from rival males compete to fertilise the ova. Studies of experimental evolution have proven the selective action of sperm competition on male reproductive traits.
Simmons Leigh W, Firman Renée C
doaj   +1 more source

Measuring Pre- and Post-Copulatory Sexual Selection and Their Interaction in Socially Monogamous Species with Extra-Pair Paternity

Cells, 2021
When females copulate with multiple males, pre- and post-copulatory sexual selection may interact synergistically or in opposition. Studying this interaction in wild populations is complex and potentially biased, because copulation and fertilization ...
Emily Rebecca Alison Cramer
doaj   +1 more source

Modeling diffusive search by non-adaptive sperm: Empirical and computational insights.

PLoS Computational Biology
During fertilization, mammalian sperm undergo a winnowing selection process that reduces the candidate pool of potential fertilizers from ~106-1011 cells to 101-102 cells (depending on the species).
Benjamin M Brisard, Kylie D Cashwell, Stephanie M Stewart, Logan M Harrison, Aidan C Charles, Chelsea V Dennis, Ivie R Henslee, Ethan L Carrow, Heather A Belcher, Debajit Bhowmick, Paul W Vos, Maciej Majka, Martin Bier, David M Hart, Cameron A Schmidt   +14 more
doaj   +1 more source

The costs and benefits of multiple mating in a mostly monandrous wasp [PDF]

, 2015
Funding: NERC DTGThe taxonomically widespread nature of polyandry remains a puzzle. Much of the empirical work regarding the costs and benefits of multiple mating to females has, for obvious reasons, relied on species that are already highly polyandrous.
Boulton, Rebecca, Shuker, David Michael
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

A PMMA-Based Microfluidic Device for Human Sperm Evaluation and Screening on Swimming Capability and Swimming Persistence

Micromachines, 2020
The selection of high-quality sperm is essential to the success of in vitro fertilization (IVF). As human cervical mucus has a high viscosity, without enough swimming persistence, human sperm clouds cannot arrive at the ampulla to fertilize the egg.
Yimo Yan, Haoran Liu, Boxuan Zhang, Ran Liu   +3 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source