Results 191 to 200 of about 83,183 (339)

Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and Ferroptosis

Andrology, EarlyView.
ABSTRACT Background The main functions of testes are sperm production and androgen secretion in testicular befitting microenvironment. Excessive level of the reactive oxygen species (ROS) from metabolism and cellular events can lead to oxidative stress (OS) and ferroptosis, which injure the functions of mitochondria and endoplasmic reticulum (ER) of ...
Shuning Yuan, Nini Wei, Weiwei Ma, Mengting Hu, Bei Zhang, Li Gao, Chao Gao, Xiaoyu Yang, Yan Meng, Jiayin Liu, Yugui Cui   +10 more
wiley   +1 more source

Testis‐Enriched F‐Box Protein FBXO39 Is Important for Spermiogenesis and Male Fertility in Mice

Andrology, EarlyView.
ABSTRACT Background The SCF (Skp–Cullin–F‐box) complex is a major class of E3 ubiquitin ligases. F‐box proteins constitute the SCF complex and play a critical role in recognizing substrates for ubiquitination. In mice, several F‐box proteins, including FBXO36 and FBXO39, are predominantly expressed in testes.
Yuki Kaneda, Haruhiko Miyata, Masahito Ikawa   +2 more
wiley   +1 more source

Cloning and characterization of a novel sperm tail protein, NYD-SP28

, 2006
Ying Zheng, Jingjing Zhang, Lei Wang, Zuomin Zhou, Min Xu, Jianmin Li, Jia-Hao Sha   +6 more
openalex   +2 more sources

Cyclic Treatment With WIN 18,446, a Potential Male Contraceptive, is as Effective as Continuous Treatment for Suppression of Spermatogenesis in Mice

Andrology, EarlyView.
ABSTRACT Background Retinoic acid plays a critical role in spermatogenesis during both spermatogonial differentiation and spermiation. Mice lacking enzymes that synthesize retinoic acid, Aldh1a1/1a2, in the testes are infertile. WIN 18,446 reversibly inhibits spermatogenesis by inhibiting ALDH1A1/1A2 and is a promising approach to male contraception ...
Jisun Paik, Jessica M. Snyder, Haley A. Martin, John K. Amory   +3 more
wiley   +1 more source

Sperm Tail would Cause of Fertilization Failure due to the Genetic Problem [PDF]

, 2015
Yoku Kato
openalex   +1 more source

Improvement of Mouse Spermatozoa Freezing at ‐80°C With Ascorbic Acid 2‐Glucoside at Thawing Phase

Andrology, EarlyView.
ABSTRACT Background Sperm cryopreservation is the most common method to maintain a great number of mutant mouse lines. However, the use of liquid nitrogen (LN2) for freezing presents considerable problems in terms of cost, safety, and accessibility. For this reason, the storage of semen samples at ‐80° in ultra‐freezers has been increasingly used in ...
Alessia Paradiso, Renata Paoletti, Simone Cassetti, Nicola Bernabò, Barbara Barboni, Marcello Raspa, Ferdinando Scavizzi   +6 more
wiley   +1 more source

Limited Utility of a Test‐Yolk Buffer Semen Extender for Preserving Human Semen Parameters for Use in a Diagnostic Setting

Andrology, EarlyView.
ABSTRACT Background Identification of a preservation medium that accurately retains semen parameters would be advantageous for men requiring semen analysis by allowing them to produce sperm samples at home rather than on site or even facilitate ‘mail order’ semen analysis.
Alessia Schadwell, Andrew Dawkins, Tina Holton, Olivia Whiting, Peter J. I. Ellis, Sheryl T. Homa   +5 more
wiley   +1 more source

Generation of tail bearing sperm-like cells from in vitro spermatogenesis of farming goat testis

, 2022
Rakesh Bhaskar, Bijaylaxmi sahoo, Sung Soo Han, Mukesh Kumar Gupta   +3 more
openalex   +2 more sources

Computer‐Assisted Sperm Analysis (CASA) Versus Manual Evaluation and the Clinical Significance of Sperm Hyperactivated Motility

Andrology, EarlyView.
Abstract Background Semen analysis remains the first‐line diagnostic test for male infertility, although it is affected by operator subjectivity. Computer‐assisted sperm analysis (CASA) is proposed to improve objectivity; however, its accuracy and clinical relevance remain uncertain.
Maria Emanuela Ragosta, Giulia Traini, Francesca Benini, Margherita Montereggi, Federica Bini, Lara Tamburrino, Linda Vignozzi, Elisabetta Baldi, Sara Marchiani   +8 more
wiley   +1 more source

Hyperactivation and Tyrosine Phosphorylation of Cryopreserved Stallion Spermatozoa in Relation to Conventional In Vitro Fertilization Blastocyst Production

Andrology, EarlyView.
ABSTRACT Background Challenges in establishing clinical conventional in vitro fertilization (IVF) in horses include variation in sperm and oocyte quality, which can be affected by mare age. Extended preincubation of stallion spermatozoa has resulted in successful IVF.
Raul A. Gonzalez‐Castro, Carolina C. Porflidt, Alexandra L. Ash, Jacobo S. Rodriguez, Perla D. Fleury, Edward L. Squires, Elaine M. Carnevale   +6 more
wiley   +1 more source