DNA fragmentation index (DFI) as a measure of sperm quality and fertility in mice. [PDF]
Although thousands of genetically modified mouse strains have been cryopreserved by sperm freezing, the likelihood of cryorecovery success cannot be accurately predicted using conventional sperm parameters.
Li, Ming-Wen, Lloyd, KC Kent
core +1 more source
Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou +22 more
wiley +1 more source
Essential role for SUN5 in anchoring sperm head to the tail
SUN (Sad1 and UNC84 domain containing)-domain proteins are reported to reside on the nuclear membrane playing distinct roles in nuclear dynamics. SUN5 is a new member of the SUN family, with little knowledge regarding its function.
Yongliang Shang +18 more
doaj +1 more source
Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang +16 more
wiley +1 more source
The results presented in this study are the first such extensive characterization of the sperm morphometry of the blue fox (Alopex lagopus) and silver fox (Vulpes vulpes), as representatives of the family Canidae. Canine spermatozoa, especially the sperm
Katarzyna Andraszek +4 more
doaj +1 more source
Effect of chromium and vitamin C on the activity of male reproductive system in rats [PDF]
To examine the possible protective role of vitamin C (200 mg/Kg B.W) as antioxidant against chromium induced oxidative stress. 18 male albino rats (3-4month old) were randomly allocated into three groups.
H. W. K. Agwan
doaj +1 more source
PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility
PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao +7 more
wiley +1 more source
EFFECT OF GONADOTROPIN RELEASING HORMONE ON SEMEN CHARACTERISTICS IN NILI-RAVI BUFFALO BULLS [PDF]
The study was aimed at determining the effect of gonadotropin releasing hormone (GnRH) on semen characteristics in two Nili-Ravi buffalo bulls. The study was conducted in two phases.
M. SAJJAD, S. ALI, S. AKHTER AND N. ULLAH1
doaj
Enhancement of mouse sperm motility by trophinin-binding peptide
Background Trophinin is an intrinsic membrane protein that forms a complex in the cytoplasm with bystin and tastin, linking it microtubule-associated motor dynein (ATPase) in some cell types. Previously, we found that human sperm tails contain trophinin,
Park Seong +12 more
doaj +1 more source
A genetic basis for a postmeiotic X versus Y chromosome intragenomic conflict in the mouse. [PDF]
Intragenomic conflicts arise when a genetic element favours its own transmission to the detriment of others. Conflicts over sex chromosome transmission are expected to have influenced genome structure, gene regulation, and speciation.
Affara, Nabeel A. +5 more
core +4 more sources

