Results 51 to 60 of about 32,366 (262)
Xenogeneic Mitochondrial Transplantation Improves Selected Age‐Associated Phenotypes in Mice
Advanced Science, EarlyView.Yak‐derived xenogeneic mitochondrial transplantation improves selected age‐associated phenotypes in mice, enhances mitochondrial functional readouts, and engages host mitochondrial quality‐control pathways. Broad tissue biodistribution, increased ATP production and mtDNA copy number, reduced ROS levels and dysfunctional mitochondria, improved motility ...
Wenpeng Li +5 more
wiley +1 more source
Enhancement of mouse sperm motility by trophinin-binding peptide
Reproductive Biology and Endocrinology, 2012 Background Trophinin is an intrinsic membrane protein that forms a complex in the cytoplasm with bystin and tastin, linking it microtubule-associated motor dynein (ATPase) in some cell types. Previously, we found that human sperm tails contain trophinin,
Park Seong +12 more
doaj +1 more source
Spermitin: a novel mitochondrial protein in Drosophila spermatids. [PDF]
PLoS ONE, 2014 Mitochondria, important energy centers in the cell, also control sperm cell morphogenesis. Drosophila spermatids have a remarkably large mitochondrial formation called the nebenkern.
Jieyan V Chen, Timothy L Megraw
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A STUDY ON SPERM TAIL ELEMENTS IN MOUSE BLASTOCYSTS [PDF]
Reproduction, 1971 Numerous studies have been published on the ultrastructural aspects of mammalian fertilization (Szollosi & Ris, 1961; Hadek, 1963, 1969; Austin, 1968; Barros & Franklin, 1968), and several recent articles have described changes in the head of the mammalian spermatozoon following its incorporation into the egg (Szollosi, 1965, 1969; Bedford ...
H D, McReynolds, R, Hadek
openaire +2 more sources
PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression
Advanced Science, EarlyView.Protein disulfide isomerase A6 (PDIA6) is identified as an oncogenic driver in gastric cancer. PDIA6 directly binds and stabilizes SCD1 by limiting its ubiquitin–proteasome‐mediated degradation, thereby sustaining monounsaturated fatty acid (MUFA)‐enriched lipid homeostasis and lipid metabolic reprogramming.
Zhen Tian +13 more
wiley +1 more source
Analysis of ejaculate parameters and sperm morphology in roosters of initial laying strains
Czech Journal of Animal ScienceThe aim of this study was to evaluate the influence of laying hybrid lines of domestic fowl (Gallus gallus f. domestica) and their age on ejaculate parameters in roosters.
Ladislav Máchal +6 more
doaj +1 more source
Advanced Science, EarlyView.This study uncovers a metabolic‐epigenetic axis licensing zygotic genome activation (ZGA) in mouse embryos. A developmental decline in NAD+ levels activates PARP7, which mono‐ADP‐ribosylates and stabilizes UHRF1. This modification promotes the establishment of permissive histone acetylation marks, thereby facilitating timely ZGA.
Guangyi Cao +13 more
wiley +1 more source
Tales of the Tail and Sperm Head AchesChanging concepts on the prognostic significance of sperm pathologies affecting the head, neck and tail [PDF]
Asian Journal of Andrology, 2011 This article presents an update on the variable prognostic significance of different sperm pathologies in patients with severe male factor infertility due to morphology and motility disorders. Severe asthenozoospermia is one of the leading causes of male infertility as spermatozoa cannot reach the oocyte and/or penetrate normally.
Chemes, Hector Edgardo +1 more
openaire +3 more sources
Advanced Science, EarlyView.This study shows that in glioma stem cells (GSCs), RBM12 recruits ALKBH5 to remove m6A from SLC7A5 transcripts, thereby enhancing mRNA stability, which elevates large neutral amino acid (LNAA) levels and activates mTORC1, promoting GSC proliferation, self‐renewal, and tumor growth.
Hong Lei +18 more
wiley +1 more source
Effect of chromium and vitamin C on the activity of male reproductive system in rats [PDF]
Iraqi Journal of Veterinary Sciences, 2009 To examine the possible protective role of vitamin C (200 mg/Kg B.W) as antioxidant against chromium induced oxidative stress. 18 male albino rats (3-4month old) were randomly allocated into three groups.
H. W. K. Agwan
doaj +1 more source