Results 1 to 10 of about 19,592 (119)

The dynamics of ciliogenesis in prepubertal mouse meiosis reveals new clues about testis maturation [PDF]

Frontiers in Cell and Developmental Biology
Primary cilia have recently been identified in mammalian spermatocytes, but their developmental regulation during testicular maturation remains poorly understood.
I. Pérez-Moreno, P. López-Jiménez, P. López-Jiménez, H. Zapata-Polo, H. Zapata-Polo, H. Zapata-Polo, S. Pérez-Martín, S. Pérez-Martín, S. Pérez-Martín, M. López-Panadés, M. López-Panadés, J. Urtasun-Elizari, P. Barbeito, P. Barbeito, I. Roig, I. Roig, F. R. Garcia-Gonzalo, F. R. Garcia-Gonzalo, F. R. Garcia-Gonzalo, J. Page, R. Gómez   +20 more
doaj   +2 more sources

Zbtb40 Deficiency Leads to Morphological and Phenotypic Abnormalities of Spermatocytes and Spermatozoa and Causes Male Infertility

Cells, 2023
Studies on the gene regulation of spermatogenesis are of unusual significance for maintaining male reproduction and treating male infertility. Here, we have demonstrated, for the first time, that a loss of ZBTB40 function leads to abnormalities in the ...
Yinghong Cui, Mingqing Zhou, Quanyuan He, Zuping He   +3 more
doaj   +1 more source

Deletion of Hnrnpk Gene Causes Infertility in Male Mice by Disrupting Spermatogenesis

Cells, 2022
HnRNPK is a heterogeneous nuclear ribonucleoprotein (hnRNP) that has been firmly implicated in transcriptional and post-transcriptional regulation. However, the molecular mechanisms by which hnRNPK orchestrates transcriptional or post-transcriptional ...
Haixia Xu, Jiahua Guo, Wei Wu, Qiu Han, Yueru Huang, Yaling Wang, Cencen Li, Xiaofang Cheng, Pengpeng Zhang, Yongjie Xu   +9 more
doaj   +1 more source

Ultrastructural evidence of spermatogenesis in the rusty parrotfish, Scarus ferrugineus (Teleostei Scaridae). [PDF]

Journal of Bioscience and Applied Research, 2015
This work analyses the spermatogenesis in the males of Scarus ferrugineus from histological and ultrastructural points of view. This study was carried out during the period of formation of spermatozoa thus being able to determine the pattern of ...
T. Ali, S. Abdel-Aziz
doaj   +1 more source

Evaluation of the Protective Effect of Vitamin C on Spermatocytes in Rats with Pentylenetetrazole-Induced Epilepsy Using Immunohistochemistry

مجله دانشکده پزشکی اصفهان, 2020
Background: There has not been yet reports regarding the protective effect of vitamin C on spermatocytes in epileptic rats. The present study aimed to evaluate the protective role of vitamin C on numbers and structure spermatocytes in rats with ...
Rahim Golmohammadi, Hamid Reza Baghani-Aval, Batool Kamalimanesh, Sajad Afraciabi   +3 more
doaj   +1 more source

SYMPK Is Required for Meiosis and Involved in Alternative Splicing in Male Germ Cells

Frontiers in Cell and Developmental Biology, 2021
SYMPK is a scaffold protein that supports polyadenylation machinery assembly on nascent transcripts and is also involved in alternative splicing in some mammalian somatic cells. However, the role of SYMPK in germ cells remains unknown.
Rui Wu, Rui Wu, Rui Wu, Junfeng Zhan, Bo Zheng, Zhen Chen, Zhen Chen, Jianbo Li, Jianbo Li, Changrong Li, Changrong Li, Rong Liu, Rong Liu, Xinhua Zhang, Xiaoyan Huang, Mengcheng Luo, Mengcheng Luo   +16 more
doaj   +1 more source

Meiotic Chromosome Synapsis and XY-Body Formation In Vitro

Frontiers in Endocrinology, 2021
To achieve spermatogenesis in vitro, one of the most challenging processes to mimic is meiosis. Meiotic problems, like incomplete synapsis of the homologous chromosomes, or impaired homologous recombination, can cause failure of crossover formation and ...
Qijing Lei, Eden Zhang, Ans M. M. van Pelt, Geert Hamer   +3 more
doaj   +1 more source

Analysis of DNA methylation changes following Cfp1 knockout in mouse spermatocytes [PDF]

Animal Bioscience
Objective Spermatogenesis is a complex biological process that encompasses meiosis in spermatocytes and the dynamic epigenetic alterations that ensure the inheritance of genetic traits.
Chanhyeok Park, Youngsok Choi, Seonho Yoo, Hyeonwoo La, Kwonho Hong   +4 more
doaj   +1 more source

Immunohistochemical localization of glucose transporter 1 and 3 in the scrotal and abdominal testes of a dog

Laboratory Animal Research, 2017
Glucose is essential for testicular function; the uptake of carbohydrate-derived glucose by cells is mediated by glucose transporters (GLUTs). In the present study, we investigated the activity of GLUT1 and GLUT3, the two main isoforms of GLUTs found in ...
Kyu Ri Hahn, Hyo Young Jung, Dae Young Yoo, Jong Whi Kim, Yang Hee Kim, Young Kwang Jo, Geon A. Kim, Jin Young Chung, Jung Hoon Choi, In Koo Hwang, Goo Jang, Yeo Sung Yoon   +11 more
doaj   +1 more source

Emi2 Is Essential for Mouse Spermatogenesis

Cell Reports, 2017
The meiotic functions of Emi2, an inhibitor of the APC/C complex, have been best characterized in oocytes where it mediates metaphase II arrest as a component of the cytostatic factor. We generated knockout mice to determine the in vivo functions of Emi2—
Lakshmi Gopinathan, Radoslaw Szmyd, Diana Low, M. Kasim Diril, Heng-Yu Chang, Vincenzo Coppola, Kui Liu, Lino Tessarollo, Ernesto Guccione, Ans M.M. van Pelt, Philipp Kaldis   +10 more
doaj   +1 more source