Results 11 to 20 of about 36,690 (245)
Hormad1 mutation disrupts synaptonemal complex formation, recombination, and chromosome segregation in mammalian meiosis [PDF]
, 2010 Meiosis is unique to germ cells and essential for reproduction. During the first meiotic division, homologous chromosomes pair, recombine, and form chiasmata.
Choi, Y +8 more
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UBR2 of the N-end rule pathway is required for chromosome stability via histone ubiquitylation in spermatocytes and somatic cells [PDF]
, 2012 The N-end rule pathway is a proteolytic system in which its recognition components (N-recognins) recognize destabilizing N-terminal residues of short-lived proteins as an essential element of specific degrons, called N-degrons.
An, JY +12 more
core +1 more source
International Journal of Molecular Sciences, 2023 Spermatocytic tumor (ST) is a very rare disease, accounting for approximately 1% of testicular cancers. Previously classified as spermatocytic seminoma, it is currently classified within the non-germ neoplasia in-situ-derived tumors and has different clinical-pathologic features when compared with other forms of germ cell tumors (GCTs).
Simona Secondino +8 more
openaire +2 more sources
Archives of Pathology & Laboratory Medicine, 2009 Abstract Spermatocytic seminoma is a rare germ cell tumor distinct from classical seminoma, both clinically and pathologically. It affects older men, has not been associated with a history of cryptorchidism, and has no known counterpart in ovary or any other site.
Nidhi, Aggarwal, Anil V, Parwani
openaire +2 more sources
A surge of late-occurring meiotic double-strand breaks rescues synapsis abnormalities in spermatocytes of mice with hypomorphic expression of SPO11 [PDF]
, 2015 Meiosis is the biological process that, after a cycle of DNA replication, halves the cellular chromosome complement, leading to the formation of haploid gametes.
Barchi, Marco +9 more
core +3 more sources
Isolation and characterization of human spermatogonial stem cells
Reproductive Biology and Endocrinology, 2011 Background To isolate and characterization of human spermatogonial stem cells from stem spermatogonium. Methods The disassociation of spermatogonial stem cells (SSCs) were performed using enzymatic digestion of type I collagenase and trypsin.
Liu Shixue +3 more
doaj +1 more source
WNK1 is required during male pachynema to sustain fertility
iScience, 2023 Summary: WNK1 is an important regulator in many physiological functions, yet its role in male reproduction is unexplored. In the male germline, WNK1 is upregulated in preleptotene spermatocytes indicating possible function(s) in spermatogenic meiosis ...
Ru-pin Alicia Chi +11 more
doaj +1 more source
Spermatocytic Seminoma in the Rat [PDF]
Toxicologic Pathology, 1985 During the necropsy of a 2-yr-old untreated control rat from a carcinogenicity study, a tan brown nodular mass was observed within the tunica albuginea of one testis. Both testes were processed for light and transmission electron microscopy. Histologically, the testicular mass was composed of round to polyhedral cells with distinct cell boundaries ...
S N, Kim +2 more
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Reproductive Biology and Endocrinology, 2003 Several in vivo studies have reported the presence of immunoreactive transforming growth factor-β's (TGF-β's) in testicular cells at defined stages of their differentiation.
Themmen Axel PN +3 more
doaj +1 more source
Cohesin SMC1β promotes closed chromatin and controls TERRA expression at spermatocyte telomeres
Life Science Alliance, 2023 Cohesin SMC1β; ensures silencing at chromosome ends, restricts TERRA expression and RNA-DNA hybrid formation, and prevents telomer damage. Previous data showed that meiotic cohesin SMC1β protects spermatocyte telomeres from damage. The underlying reason,
Uddipta Biswas +5 more
doaj +1 more source