Results 141 to 150 of about 26,767 (249)
A mei-P26 is required for initiation of meiosis in the Drosophila male germline
Mei-P26, a member of the TRIM-NHL family, plays a pivotal role in Drosophila germline development, including female meiosis. However, its role in male meiosis remains unclear.
Mai Oda, Yuri Tanaka, Yoshihiro H. Inoue
doaj +1 more source
A Noncanonical Protein Degradation Pathway That Regulates Germ Cell Maintenance
SENP8 regulates a non‐canonical NEDD8‐dependent pathway to stabilize STAT1, promote CCL2/CCL5 transcription, and maintain germ cell proliferation and migration.
Meng Liu +11 more
wiley +1 more source
SIRT1, an NAD+‐dependent deacetylase, supports cognitive resilience by coordinating neuroprotection, synaptic plasticity, autophagy–lysosomal proteostasis, and mitochondrial energy homeostasis. Reduced or dysregulated SIRT1 is associated with protein aggregation, neuroinflammation, mitochondrial dysfunction, synaptic loss, and cognitive decline in ...
Jiabin Duan +6 more
wiley +1 more source
Pachytene arrest of UBR2−/− spermatocytes at stage IV.
(A–D) Testis sections from 8-week (A–C) and 3-week (D) old UBR2−/− tubules. (A) Tubules that did not yet reach epithelial stage IV. A large number of spermatocytes (thick arrow) are present, indicating that the spermatogonial compartment keeps forming ...
Adriana Zakrzewska (164235) +12 more
core +1 more source
RAD51 foci persist in Mof deleted pachytene and diplotene spermatocytes.
Immunofluorescence staining for SYCP3 (red), RAD51 (green) and H1T (blue) in control and Mof cKO spermatocytes at early pachynema (A), late pachynema (C) and diplonema (E). Scale bars, 10 μm.
Qinghua Shi (169845) +14 more
core +1 more source
Transforming acidic acid coiled-coil protein 3 (TACC3) and cytoskeleton associated protein 5 (cKAP5; or colonic hepatic tumor overexpressed gene, chTOG) are vital for spindle assembly and stabilization initiated through TACC3 Aurora-A kinase interaction.
Calvin Simerly +7 more
doaj +1 more source
Ubc9 Mediates SUMO2/3 Modification to Regulate Meiosis in Male Mice. [PDF]
Lv P +6 more
europepmc +1 more source
Epigenetic dynamics of human spermatogenesis and their dysregulation in non-obstructive azoospermia. [PDF]
Xie H +8 more
europepmc +1 more source
Postnatal Cell-Type-Specific Localization of EGFR and Its Ligands (EGF, TGF-α and AREG) in the Rat Testis. [PDF]
Alesawi YAK, Ergün E.
europepmc +1 more source

