Results 141 to 150 of about 26,767 (249)

A mei-P26 is required for initiation of meiosis in the Drosophila male germline

open access: yesCell Structure and Function
Mei-P26, a member of the TRIM-NHL family, plays a pivotal role in Drosophila germline development, including female meiosis. However, its role in male meiosis remains unclear.
Mai Oda, Yuri Tanaka, Yoshihiro H. Inoue
doaj   +1 more source

A Noncanonical Protein Degradation Pathway That Regulates Germ Cell Maintenance

open access: yesCell Proliferation, Volume 59, Issue 10, October 2026.
SENP8 regulates a non‐canonical NEDD8‐dependent pathway to stabilize STAT1, promote CCL2/CCL5 transcription, and maintain germ cell proliferation and migration.
Meng Liu   +11 more
wiley   +1 more source

SIRT1 in Neurodegenerative Diseases: Molecular Mechanisms, Disease Relevance, and Therapeutic Potential

open access: yesThe FASEB Journal, Volume 40, Issue 17, 15 September 2026.
SIRT1, an NAD+‐dependent deacetylase, supports cognitive resilience by coordinating neuroprotection, synaptic plasticity, autophagy–lysosomal proteostasis, and mitochondrial energy homeostasis. Reduced or dysregulated SIRT1 is associated with protein aggregation, neuroinflammation, mitochondrial dysfunction, synaptic loss, and cognitive decline in ...
Jiabin Duan   +6 more
wiley   +1 more source

Pachytene arrest of UBR2−/− spermatocytes at stage IV.

open access: yes, 2012
(A–D) Testis sections from 8-week (A–C) and 3-week (D) old UBR2−/− tubules. (A) Tubules that did not yet reach epithelial stage IV. A large number of spermatocytes (thick arrow) are present, indicating that the spermatogonial compartment keeps forming ...
Adriana Zakrzewska (164235)   +12 more
core   +1 more source

RAD51 foci persist in Mof deleted pachytene and diplotene spermatocytes.

open access: yes, 2018
Immunofluorescence staining for SYCP3 (red), RAD51 (green) and H1T (blue) in control and Mof cKO spermatocytes at early pachynema (A), late pachynema (C) and diplonema (E). Scale bars, 10 μm.
Qinghua Shi (169845)   +14 more
core   +1 more source

Male meiotic spindle poles are stabilized by TACC3 and cKAP5/chTOG differently from female meiotic or somatic mitotic spindles in mice

open access: yesScientific Reports
Transforming acidic acid coiled-coil protein 3 (TACC3) and cytoskeleton associated protein 5 (cKAP5; or colonic hepatic tumor overexpressed gene, chTOG) are vital for spindle assembly and stabilization initiated through TACC3 Aurora-A kinase interaction.
Calvin Simerly   +7 more
doaj   +1 more source

Ubc9 Mediates SUMO2/3 Modification to Regulate Meiosis in Male Mice. [PDF]

open access: yesBiomedicines
Lv P   +6 more
europepmc   +1 more source

Epigenetic dynamics of human spermatogenesis and their dysregulation in non-obstructive azoospermia. [PDF]

open access: yesProtein Cell
Xie H   +8 more
europepmc   +1 more source

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