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Ubiquitin-Proteasome System–Regulated Protein Degradation in Spermatogenesis
Cells, 2022 Spermatogenesis is a prolonged and highly ordered physiological process that produces haploid male germ cells through more than 40 steps and experiences dramatic morphological and cellular transformations.
Yi Xiong, Chao Yu, Qianting Zhang
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Genes Regulating Spermatogenesis and Sperm Function Associated With Rare Disorders
Frontiers in Cell and Developmental Biology, 2021 Spermatogenesis is a cell differentiation process that ensures the production of fertilizing sperm, which ultimately fuse with an egg to form a zygote.
Emma Linn +4 more
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Novel Gene Regulation in Normal and Abnormal Spermatogenesis
Cells, 2021 Spermatogenesis is a complex and dynamic process which is precisely controlledby genetic and epigenetic factors. With the development of new technologies (e.g., single-cell RNA sequencing), increasingly more regulatory genes related to spermatogenesis ...
Li Du +7 more
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Advances in research on RNA N-6-methyladenosine(m6A) modification related enzymes in mammalian spermatogenesis [PDF]
Jichu yixue yu linchuang, 2023 N-6-methyladenosine(m6A) has been well-known to be a type of RNA epigenetic modification over the past decade. The m6A modification enzymes include “Writers” (METTL3/14/WTAP, etc.),“Erasers” (FTO and ALKBH5) and “Readers” (YTHDC1/2,YTHDF1/2/3, etc ...
ZHANG Qiang, SU Wenhui
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International Journal of Molecular Sciences, 2021 Spermatogenesis and folliculogenesis involve cell–cell interactions and gene expression orchestrated by luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
O. Oduwole, I. Huhtaniemi, M. Misrahi
semanticscholar +1 more source
Mitochondrial Functionality in Male Fertility: From Spermatogenesis to Fertilization
Antioxidants, 2021 Mitochondria are structurally and functionally distinct organelles that produce adenosine triphosphate (ATP) through oxidative phosphorylation (OXPHOS), to provide energy to spermatozoa. They can also produce reactive oxidation species (ROS).
Yoo-Jin Park, M. Pang
semanticscholar +1 more source
Gut, 2021 Objective Effects of the diet-induced gut microbiota dysbiosis reach far beyond the gut. We aim to uncover the direct evidence involving the gut–testis axis in the aetiology of impaired spermatogenesis.
Teng Zhang +9 more
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Cells, 2022 Spermatogenesis is a complex process occurring in mammalian testes, and constant sperm production depends on the exact regulation of the microenvironment in the testes.
Yu Zhou, Yunyan Wang
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In vitro mouse spermatogenesis with an organ culture method in chemically defined medium. [PDF]
PLoS ONE, 2018 We previously reported the successful induction and completion of mouse spermatogenesis by culturing neonatal testis tissues. The culture medium consisted of α-minimum essential medium (α-MEM), supplemented with Knockout serum replacement (KSR) or ...
Hiroyuki Sanjo +13 more
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Three-Dimensional Analysis of Busulfan-Induced Spermatogenesis Disorder in Mice
Frontiers in Cell and Developmental Biology, 2020 We examined if the distribution of impaired or normal spermatogenesis differs along the length of seminiferous tubules in disorders of spermatogenesis. For this purpose, three-dimensional (3D) reconstruction of seminiferous tubules was performed in mice ...
Hiroki Nakata +3 more
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