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Induction of Spermatogenesis and Its Predictors in Men with Prepubertal-Onset Hypogonadotropic Hypogonadism Undergoing Gonadotropin Therapy [PDF]
The World Journal of Men's HealthPurpose: To evaluate the outcomes of gonadotropin therapy (GT) using human chorionic gonadotropin (hCG) and recombinant follicle-stimulating hormone (rFSH) for inducing spermatogenesis in men with prepubertal-onset hypogonadotropic hypogonadism (HH ...
Min Chul Cho, Hohyun Lee, Soo Woong Kim
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Advances in research on RNA N-6-methyladenosine(m6A) modification related enzymes in mammalian spermatogenesis [PDF]
Jichu yixue yu linchuang, 2023 N-6-methyladenosine(m6A) has been well-known to be a type of RNA epigenetic modification over the past decade. The m6A modification enzymes include “Writers” (METTL3/14/WTAP, etc.),“Erasers” (FTO and ALKBH5) and “Readers” (YTHDC1/2,YTHDF1/2/3, etc ...
ZHANG Qiang, SU Wenhui
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Current Biology, 2017 Most organisms consist of two cell lineages - somatic cells and germ cells. The former are required for the current generation, and the latter create offspring. Male and female germ cells are usually produced during spermatogenesis and oogenesis, which take place in the testis and the ovary, respectively. Spermatogenesis involves the differentiation of
Toppari Jorma, Mäkelä Juho-Antti
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Cells, 2022 Spermatogenesis is a complex process occurring in mammalian testes, and constant sperm production depends on the exact regulation of the microenvironment in the testes.
Yu Zhou, Yunyan Wang
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Functions of somatic cells for spermatogenesis in stallions
Journal of Animal Science and Technology, 2022 Spermatogenesis and testis development are highly structured physiological processes responsible for post-pubertal fertility in stallions. Spermatogenesis comprises spermatocytogenesis, meiosis, and spermiogenesis.
Muhammad Shakeel, Minjung Yoon
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Transcriptome profiling of developing testes and spermatogenesis in the Mongolian horse
BMC Genetics, 2020 Background Horse testis development and spermatogenesis are complex physiological processes. Methods To study these processes, three immature and three mature testes were collected from the Mongolian horse, and six libraries were established using high ...
Bei Li +8 more
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Human Reproduction, 1998 Spermatogenesis is a complex process involving mitotic cell division, meiosis and the process of spermiogenesis. The regulation of spermatogenesis involves both endocrine and paracrine mechanisms. The endocrine stimulation of spermatogenesis involves both follicle stimulating hormone (FSH) and luteinizing hormone, the latter acting through the ...
D M, de Kretser +4 more
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Three-Dimensional Analysis of Busulfan-Induced Spermatogenesis Disorder in Mice
Frontiers in Cell and Developmental Biology, 2020 We examined if the distribution of impaired or normal spermatogenesis differs along the length of seminiferous tubules in disorders of spermatogenesis. For this purpose, three-dimensional (3D) reconstruction of seminiferous tubules was performed in mice ...
Hiroki Nakata +3 more
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In vitro mouse spermatogenesis with an organ culture method in chemically defined medium. [PDF]
PLoS ONE, 2018 We previously reported the successful induction and completion of mouse spermatogenesis by culturing neonatal testis tissues. The culture medium consisted of α-minimum essential medium (α-MEM), supplemented with Knockout serum replacement (KSR) or ...
Hiroyuki Sanjo +13 more
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Spermatogenesis and Cryptorchidism [PDF]
Frontiers in Endocrinology, 2014 Cryptorchidism represents the most common endocrine disease in boys, with infertility more frequently observed in bilateral forms. It is also known that undescended testes, if untreated, lead to an increased risk of testicular tumors, usually seminomas, arising from mutant germ cells.
Cobellis G +7 more
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