Results 11 to 20 of about 102,741 (261)
Ubiquitin-Proteasome System–Regulated Protein Degradation in Spermatogenesis
Spermatogenesis is a prolonged and highly ordered physiological process that produces haploid male germ cells through more than 40 steps and experiences dramatic morphological and cellular transformations.
Yi Xiong, Chao Yu, Qianting Zhang
doaj +2 more sources
Genes Regulating Spermatogenesis and Sperm Function Associated With Rare Disorders
Spermatogenesis is a cell differentiation process that ensures the production of fertilizing sperm, which ultimately fuse with an egg to form a zygote.
Emma Linn +4 more
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Novel Gene Regulation in Normal and Abnormal Spermatogenesis
Spermatogenesis is a complex and dynamic process which is precisely controlledby genetic and epigenetic factors. With the development of new technologies (e.g., single-cell RNA sequencing), increasingly more regulatory genes related to spermatogenesis ...
Li Du +7 more
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Spermatogenesis and folliculogenesis involve cell–cell interactions and gene expression orchestrated by luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
O. Oduwole, I. Huhtaniemi, M. Misrahi
semanticscholar +1 more source
Copper (Cu) is a necessary micronutrient at lower concentration, while excessive Cu exposure or Cu homeostasis disorders can lead to toxicity. The mechanism of male reproductive toxicity induced by Cu is still unknown.
Hongrui Guo +13 more
semanticscholar +1 more source
Mitochondrial Functionality in Male Fertility: From Spermatogenesis to Fertilization
Mitochondria are structurally and functionally distinct organelles that produce adenosine triphosphate (ATP) through oxidative phosphorylation (OXPHOS), to provide energy to spermatozoa. They can also produce reactive oxidation species (ROS).
Yoo-Jin Park, M. Pang
semanticscholar +1 more source
The molecular evolution of spermatogenesis across mammals
The testis produces gametes through spermatogenesis and evolves rapidly at both the morphological and molecular level in mammals^ 1 – 6 , probably owing to the evolutionary pressure on males to be reproductively successful^ 7 .
Florent Murat +23 more
semanticscholar +1 more source
Objective Effects of the diet-induced gut microbiota dysbiosis reach far beyond the gut. We aim to uncover the direct evidence involving the gut–testis axis in the aetiology of impaired spermatogenesis.
Teng Zhang +9 more
semanticscholar +1 more source
In vitro mouse spermatogenesis with an organ culture method in chemically defined medium. [PDF]
We previously reported the successful induction and completion of mouse spermatogenesis by culturing neonatal testis tissues. The culture medium consisted of α-minimum essential medium (α-MEM), supplemented with Knockout serum replacement (KSR) or ...
Hiroyuki Sanjo +13 more
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Spermatogenesis is a complex and continuous process of germ-cell differentiation. This complex process is regulated by many factors, of which gene regulation in spermatogenic cells plays a decisive role.
Yanan Li +11 more
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