Results 11 to 20 of about 109,586 (294)

Three-Dimensional Analysis of Busulfan-Induced Spermatogenesis Disorder in Mice

Frontiers in Cell and Developmental Biology, 2020
We examined if the distribution of impaired or normal spermatogenesis differs along the length of seminiferous tubules in disorders of spermatogenesis. For this purpose, three-dimensional (3D) reconstruction of seminiferous tubules was performed in mice ...
Hiroki Nakata, Taito Nakano, Shoichi Iseki, Atsushi Mizokami   +3 more
doaj   +1 more source

In vitro mouse spermatogenesis with an organ culture method in chemically defined medium. [PDF]

PLoS ONE, 2018
We previously reported the successful induction and completion of mouse spermatogenesis by culturing neonatal testis tissues. The culture medium consisted of α-minimum essential medium (α-MEM), supplemented with Knockout serum replacement (KSR) or ...
Hiroyuki Sanjo, Mitsuru Komeya, Takuya Sato, Takeru Abe, Kumiko Katagiri, Hiroyuki Yamanaka, Yoko Ino, Noriaki Arakawa, Hisashi Hirano, Tatsuma Yao, Yuta Asayama, Akio Matsuhisa, Masahiro Yao, Takehiko Ogawa   +13 more
doaj   +1 more source

Transcriptome profiling of developing testes and spermatogenesis in the Mongolian horse

BMC Genetics, 2020
Background Horse testis development and spermatogenesis are complex physiological processes. Methods To study these processes, three immature and three mature testes were collected from the Mongolian horse, and six libraries were established using high ...
Bei Li, Xiaolong He, Yiping Zhao, Dongyi Bai, Ming Du, Lianjie Song, Zhuang Liu, Zhenchen Yin, Dugarjaviin Manglai   +8 more
doaj   +1 more source

Impairment of spermatogenesis and sperm motility by the high-fat diet-induced dysbiosis of gut microbes

Gut, 2020
Objective High-fat diet (HFD)-induced metabolic disorders can lead to impaired sperm production. We aim to investigate if HFD-induced gut microbiota dysbiosis can functionally influence spermatogenesis and sperm motility.
Ning Ding, Xin Zhang, Xue Di Zhang, Jun Jing, Sha Liu, Y. Mu, Li Li Peng, Yunjing Yan, Geng Miao Xiao, Xinyun Bi, Haojun Chen, F. Li, B. Yao, A. Zhao   +13 more
semanticscholar   +1 more source

Roles of Spermatogonial Stem Cells in Spermatogenesis and Fertility Restoration

Frontiers in Endocrinology, 2022
Spermatogonial stem cells (SSCs) are a group of adult stem cells in the testis that serve as the foundation of continuous spermatogenesis and male fertility.
Lei Diao, P. Turek, C. M. John, Fang Fang, R. R. Reijo Pera   +4 more
semanticscholar   +1 more source

Single-Cell RNA Sequencing of the Testis of Ciona intestinalis Reveals the Dynamic Transcriptional Profile of Spermatogenesis in Protochordates

Cells, 2022
Spermatogenesis is a complex and continuous process of germ-cell differentiation. This complex process is regulated by many factors, of which gene regulation in spermatogenic cells plays a decisive role.
Yanan Li, Xiang Liu, Xianghui Zhang, Hongyan Wang, Jianyang Chen, Jiankai Wei, Yubang Li, Hongxi Chen, Qian Wang, Kaiqiang Liu, Yuyan Liu, Changwei Shao   +11 more
doaj   +1 more source

Single-cell RNA sequencing of human, macaque, and mouse testes uncovers conserved and divergent features of mammalian spermatogenesis

bioRxiv, 2020
Spermatogenesis is a highly regulated process that produces sperm to transmit genetic information to the next generation. Although extensively studied in mice, our current understanding of primate spermatogenesis is limited to populations defined by ...
A. Shami, Xianing Zheng, S. Munyoki, Qianyi Ma, Gabriel Manske, C. D. Green, M. Sukhwani, K. Orwig, Jun Z. Li, S. S. Hammoud   +9 more
semanticscholar   +1 more source

Proteomic analysis and miRNA profiling of human testicular endothelial cell-derived exosomes: the potential effects on spermatogenesis

Asian Journal of Andrology, 2022
Testicular endothelial cells have been found to play an important role in spermatogenesis and fertility, but their mechanism is obscure. Exosomes released by various cells are recognized as cell–cell communication mediators during the initiation and ...
Wen-Peng Song, Sheng-Ji Gu, Xiao-Hui Tan, Yang-Yang Gu, Wei-Dong Song, Jian-Yu Zeng, Zhong-Cheng Xin, Rui-Li Guan   +7 more
doaj   +1 more source

Transcriptome profiling of laser-captured germ cells and functional characterization of zbtb40 during 17alpha-methyltestosterone-induced spermatogenesis in orange-spotted grouper (Epinephelus coioides)

BMC Genomics, 2020
Background Spermatogenesis is an intricate process regulated by a finely organized network. The orange-spotted grouper (Epinephelus coioides) is a protogynous hermaphroditic fish, but the regulatory mechanism of its spermatogenesis is not well-understood.
Xi Wu, Yang Yang, Chaoyue Zhong, Yin Guo, Shuisheng Li, Haoran Lin, Xiaochun Liu   +6 more
doaj   +1 more source

PENGARUH PEMBERIAN RANITIDINE TERHADAP SPERMATOGENESIS TIKUS Wistar DENGAN INTOKSIKASI METANOL AKUT DILIHAT SECARA HISTOPATOLOGIS

Jurnal Kedokteran Diponegoro, 2017
Latar belakang: Metanol memiliki efek toksik melalui metabolitnya yaitu asam format yang mengakibatkan gangguan spermatogenesis. Ranitidine mempunyai enzim yang dapat menghambat terbentuknya metabolit asam format sehingga diharapkan akan mengurangi efek ...
James Otniel, Muhammad Thohar Arifin, Ika Pawitra Miranti   +2 more
doaj   +1 more source