Results 31 to 40 of about 109,586 (294)
Loss-of-function analysis reveals distinct requirements of the translation initiation factors eIF4E, eIF4E-3, eIF4G and eIF4G2 in Drosophila spermatogenesis. [PDF]
PLoS ONE, 2015 In eukaryotes, post-transcriptional regulation of gene expression has a key role in many cellular and developmental processes. Spermatogenesis involves a complex developmental program that includes changes in cell cycle dynamics and dramatic cellular ...
Sanjay Ghosh, Paul Lasko
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In vivo functions of miRNAs in mammalian spermatogenesis
Frontiers in Cell and Developmental Biology, 2023 MicroRNAs (miRNAs) are believed to play important roles in mammalian spermatogenesis mainly because spermatogenesis is more or less disrupted when genes encoding key enzymes for miRNA biogenesis are mutated.
Jian Chen +6 more
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Gut, 2020 Very recent publications in Gut and elsewhere1 2 suggest that gut microbiota affects fertility. The application of faecal microbiota transplantation (FMT) to modify fertility is an emerging novel area of interest.3 FMT from women with polycystic ovary ...
Pengfei Zhang +15 more
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Antipsychotics and spermatogenesis, which is the impact?: A review of literature
European Psychiatry, 2023 Introduction Antipsychotics are among the most widely prescribed molecules in psychiatry. Their sexual side effects are frequent, generally underestimated by clinicians and subjectively poorly tolerated by patients.
H. Belhadga, Z. Elmaataoui, H. Kisra
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Theranostics, 2020 Rationale: Busulfan is currently an indispensable anti-cancer drug, particularly for children, but the side effects on male reproduction are so serious that critical drug management is needed to minimize any negative impact.
Yong Zhao +7 more
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Single-cell RNA-seq uncovers dynamic processes and critical regulators in mouse spermatogenesis
Cell Research, 2018 A systematic interrogation of male germ cells is key to complete understanding of molecular mechanisms governing spermatogenesis and the development of new strategies for infertility therapies and male contraception. Here we develop an approach to purify
Yao Chen +14 more
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Dissecting mammalian spermatogenesis using spatial transcriptomics
bioRxiv, 2020 Single-cell RNA sequencing has revealed extensive molecular diversity in gene programs governing mammalian spermatogenesis but fails to delineate their dynamics in the native context of seminiferous tubules — the spatially-confined functional units of ...
Haiqi Chen +12 more
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The Prmt5-Vasa module is essential for spermatogenesis in Bombyx mori.
PLoS Genetics, 2023 In lepidopteran insects, dichotomous spermatogenesis produces eupyrene spermatozoa, which are nucleated, and apyrene spermatozoa, which are anucleated.
Xu Yang +12 more
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Multiple signaling pathways in Sertoli cells: recent findings in spermatogenesis
Cell Death and Disease, 2019 The functions of Sertoli cells in spermatogenesis have attracted much more attention recently. Normal spermatogenesis depends on Sertoli cells, mainly due to their influence on nutrient supply, maintenance of cell junctions, and support for germ cells ...
Fei-da Ni, Shuang-li Hao, Wan-Xi Yang
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Epi-mutations for spermatogenic defects by maternal exposure to di(2-ethylhexyl) phthalate
eLife, 2021 Exposure to environmental factors during fetal development may lead to epigenomic modifications in fetal germ cells, altering gene expression and promoting diseases in successive generations.
Yukiko Tando +5 more
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