Results 31 to 40 of about 102,741 (261)

Gene expression profiles of mouse spermatogenesis during recovery from irradiation

Reproductive Biology and Endocrinology, 2009
Background Irradiation or chemotherapy that suspend normal spermatogenesis is commonly used to treat various cancers. Fortunately, spermatogenesis in many cases can be restored after such treatments but knowledge is limited about the re-initiation ...
Skakkebæk Niels E, Kobayashi Shinichi, Iwamoto Teruaki, Nielsen John E, Tanaka Masami, Shah Fozia J, Leffers Henrik, Almstrup Kristian   +7 more
doaj   +1 more source

Pathological and molecular examinations of postmortem testis biopsies reveal SARS-CoV-2 infection in the testis and spermatogenesis damage in COVID-19 patients

Cellular & Molecular Immunology, 2020
In late December 2019, the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), was identi fi ed in Wuhan, China, and the ensuing pandemic has led to more than 50 million infected ...
Xixiang Ma, C. Guan, Rong Chen, Yunyun Wang, Shenglei Feng, Rongshuai Wang, G. Qu, Sijia Zhao, Fengli Wang, Xiaoli Wang, Dingyu Zhang, Liang Liu, A. Liao, Shuiqiao Yuan   +13 more
semanticscholar   +1 more source

Testicular miRNAs in relation to spermatogenesis, spermatogonial stem cells and cancer/testis genes

Scientific African, 2019
The process of spermatogenesis in human involves three organized biological processes, through which spermatogonia cells undergo mitosis, meiosis and finally differentiation into mature spermatozoa.
Maryam Beigom Mobasheri, Kehinde Adebayo Babatunde   +1 more
doaj   +1 more source

The Mammalian Spermatogenesis Single-Cell Transcriptome, from Spermatogonial Stem Cells to Spermatids.

Cell Reports, 2018
Spermatogenesis is a complex and dynamic cellular differentiation process critical to male reproduction and sustained by spermatogonial stem cells (SSCs).
B. Hermann, K. Cheng, Anukriti Singh, Lorena Roa-de la Cruz, K. Mutoji, I-Chung Chen, Heidi Gildersleeve, Jake D Lehle, Max Mayo, B. Westernströer, N. C. Law, M. Oatley, Ellen K. Velte, Bryan A. Niedenberger, D. Fritze, S. Silber, C. Geyer, J. Oatley, J. McCarrey   +18 more
semanticscholar   +1 more source

In Vitro Spermatogenesis in Explanted Adult Mouse Testis Tissues. [PDF]

PLoS ONE, 2015
Research on in vitro spermatogenesis is important for elucidating the spermatogenic mechanism. We previously developed an organ culture method which can support spermatogenesis from spermatogonial stem cells up to sperm formation using immature mouse ...
Takuya Sato, Kumiko Katagiri, Kazuaki Kojima, Mitsuru Komeya, Masahiro Yao, Takehiko Ogawa   +5 more
doaj   +1 more source

Multi-omics analysis reveals that iron deficiency impairs spermatogenesis by gut-hormone synthesis axis

Ecotoxicology and Environmental Safety, 2022
Considering that research has mainly focussed on how excessive iron supplementation leads to reproductive cytotoxicity, there is a lack of in-depth research on reproductive system disorders caused by iron deficiency. To gain a better understanding of the
Fa-Li Zhang, Shuai Yuan, Pei-Yu Dong, Hao-Hai Ma, Massimo De Felici, Wei Shen, Xi-Feng Zhang   +6 more
doaj   +1 more source

Chromatin-Associated Protein Sugp2 Involved in mRNA Alternative Splicing During Mouse Spermatogenesis

Frontiers in Veterinary Science, 2021
Mammalian spermatogenesis is a highly ordered process that is determined by chromatin-associated moderators which still remain poorly understood. Through a multi-control group proteomics strategy, we confirmed that Sugp2 was a chromatin-associated ...
Junfeng Zhan, Junfeng Zhan, Junfeng Zhan, Jianbo Li, Jianbo Li, Yuerong Wu, Panfeng Wu, Panfeng Wu, Ziqi Yu, Ziqi Yu, Peng Cui, Peng Cui, Mofan Zhou, Yumin Xu, Yumin Xu, Tingyu Jin, Tingyu Jin, Ziye Du, Ziye Du, Mengcheng Luo, Mengcheng Luo, Cong Liu, Cong Liu   +22 more
doaj   +1 more source

Long non-coding RNAs (lncRNAs) in spermatogenesis and male infertility

Reproductive Biology and Endocrinology, 2020
Background Long non-coding RNAs (lncRNAs) have a size of more than 200 bp and are known to regulate a host of crucial cellular processes like proliferation, differentiation and apoptosis by regulating gene expression.
Meghali Joshi, S. Rajender
semanticscholar   +1 more source

Loss-of-function analysis reveals distinct requirements of the translation initiation factors eIF4E, eIF4E-3, eIF4G and eIF4G2 in Drosophila spermatogenesis. [PDF]

PLoS ONE, 2015
In eukaryotes, post-transcriptional regulation of gene expression has a key role in many cellular and developmental processes. Spermatogenesis involves a complex developmental program that includes changes in cell cycle dynamics and dramatic cellular ...
Sanjay Ghosh, Paul Lasko
doaj   +1 more source

In vivo functions of miRNAs in mammalian spermatogenesis

Frontiers in Cell and Developmental Biology, 2023
MicroRNAs (miRNAs) are believed to play important roles in mammalian spermatogenesis mainly because spermatogenesis is more or less disrupted when genes encoding key enzymes for miRNA biogenesis are mutated.
Jian Chen, Jian Chen, Jian Chen, Chunsheng Han, Chunsheng Han, Chunsheng Han, Chunsheng Han   +6 more
doaj   +1 more source