Results 31 to 40 of about 58,630 (199)

Reproductive adverse events in patients with non‐Hodgkin lymphoma treated with chemotherapeutic regimens including cyclophosphamide, doxorubicin, vincristine, prednisone or CHOP with rituximab: A systematic review and meta‐analysis

Pediatric Discovery, EarlyView.
The regimen of cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) or CHOP with rituximab (R‐CHOP) is the first‐line treatment for non‐Hodgkin lymphoma (NHL). Nine articles involving 331 patients were included in the meta‐analysis, the pooled proportion of reproductive adverse events was 22.3% (95% CI 11.4%–33.2%; p < 0.001). The findings
Rong Han, Jie Zhao, Chengjun Yu, Ling Wang, Long Chen, Yang Hu, Shengde Wu   +6 more
wiley   +1 more source

Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire

PROTEOMICS, EarlyView.
ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley   +1 more source

Emerging trends in the management of non‐obstructive azoospermia

UroPrecision, EarlyView.
Abstract Ten percent of infertile males have azoospermia, classified into obstructive and nonobstructive types, which require specific medical or surgical treatments. In nonobstructive azoospermia, advancements in microsurgery allow for effective sperm retrieval in about half of cases.
Mina Saad, Mohamed Alkabeer, Dina Abdelmonim, Sameh Fayek GamalElDin, Mohamed Wael Ragab   +4 more
wiley   +1 more source

Surgical outcomes in male reconstructive urology: The Qatar experience

UroPrecision, EarlyView.
Abstract Introduction Obstructive azoospermia (OA) is a prevalent cause of male infertility in Qatar and globally, with vasectomy reversal (VV) and vasoepididymostomy (VE) being the primary surgical treatments. While microsurgical techniques have advanced, data from the Middle East remain limited, influenced by the region's distinct demographic and ...
Kareim Khalafalla, Ahmad Majzoub, Ahmed Al Saeedi, Mohammed Mahdi, Mohamed Arafa, Ahmad AlMalki, Khalid AlKubaisi, Sami AlSaid, Haitham ElBardisi   +8 more
wiley   +1 more source

Isolated asthenozoospermia: What should we know? A narrative review of literature

UroPrecision, EarlyView.
ABSTRACT Male infertility contributes to 20%–70% of infertile couple cases worldwide. One of the key challenges in this area is asthenozoospermia or reduced sperm motility. A particular subset, known as isolated asthenozoospermia (iASZ), in which low motility occurs without abnormalities in sperm count or shape, often goes unnoticed and is not well ...
Ahmed Eissa, Khaled Almekaty, Ahmed Zoeir, Hussein Mamdoh, Ayman Mousa, Mohammed Abou‐elenein, Tarek Gameel, Maged Ragab   +7 more
wiley   +1 more source

Systematic review and meta‐analysis of COVID‐19 association with human semen quality: Changes in semen parameters pre‐ and post‐COVID

UroPrecision, EarlyView.
Abstract Coronavirus disease (COVID‐19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), which may infect the cells through binding with the angiotensin‐converting enzyme 2 (ACE2) receptors that can also be found in the male reproductive organs.
Wempy Supit, Tommy Supit, Sherryn Sherryn   +2 more
wiley   +1 more source

From clinical observations to molecular insights: Decoding immune checkpoint inhibitors‐induced prostatitis

VIEW, EarlyView.
Immune checkpoint inhibitors (ICIs), an innovative class of cancer therapeutics, may elevate the risk of prostate inflammation (prostatitis) in a subset of male patients. Our investigation demonstrated that ICIs can induce inflammatory responses in prostate tissue; however, selectively targeting specific inflammatory pathways may potentially mitigate ...
Peng Luo, Ying Liu, Lan Xu, Zaoqu Liu, Linhui Wang, Hank Z. H. Wong, Quan Cheng, Anqi Lin, Xiao Fang, Aimin Jiang   +9 more
wiley   +1 more source

Glycopattern comparison of sperm and exosomes from conventional in vitro fertilization and rescue intracytoplasmic sperm injection: Enhancing sperm motility through exosome‐mediated glycan modulation

VIEW, EarlyView.
Infertility is a global concern, with male factors contributing to nearly half of cases. This study compared glycopatterns of sperm and sperm‐derived exosomes from conventional IVF and rescue ICSI (RICSI) patients, revealing key differences in glycan expression.
Muhammad Anas Ramzan, Zhedong Yang, Li Cao, Jinyuan Zhang, Fei Wu, Miaomiao Xin, Bo Guo, Lumin Wang, Lingyu Zhao, Yannan Qin, Chengcheng Liu   +10 more
wiley   +1 more source

Adaptive divergence in reproductive seasonality and underlying physiological features fit Rattus norvegicus to live as opportunistic breeders

Integrative Zoology, EarlyView.
Brown rats living at different latitudes have evolved reproductive patterns adapted to their local environments. Besides expected adaptive divergence in seasonality, a distinct regulating mechanism from typical seasonal breeders reveals how brown rats benefit from quicker semen production to live as opportunistic breeders.
Xixuan LI, Ning LI, Dandan YAO, Yu LIU, Ying SONG, Dawei WANG, Zhiyong FENG, Xiaohui LIU   +7 more
wiley   +1 more source

Strong Signatures of Selection on Candidate Genes Underlying Core Speciation Mechanisms in Desert Tortoises

Molecular Ecology Resources, EarlyView.
ABSTRACT Genomic incompatibilities and differential ecological adaptation are thought to be fundamental mechanisms of speciation. In this study, we generated a chromosome‐scale reference genome and annotation for Gopherus morafkai , the Sonoran Desert tortoise, and conducted a detailed analysis of genes under positive selection with its sister species,
Sarah M. Baty, Raúl Araya‐Donoso, Avery Paulsen, Avery Williams, Dale F. DeNardo, Kenro Kusumi, Greer A. Dolby   +6 more
wiley   +1 more source