Results 31 to 40 of about 66,364 (295)

Loss-of-function analysis reveals distinct requirements of the translation initiation factors eIF4E, eIF4E-3, eIF4G and eIF4G2 in Drosophila spermatogenesis. [PDF]

open access: yesPLoS ONE, 2015
In eukaryotes, post-transcriptional regulation of gene expression has a key role in many cellular and developmental processes. Spermatogenesis involves a complex developmental program that includes changes in cell cycle dynamics and dramatic cellular ...
Sanjay Ghosh, Paul Lasko
doaj   +1 more source

In vivo functions of miRNAs in mammalian spermatogenesis

open access: yesFrontiers in Cell and Developmental Biology, 2023
MicroRNAs (miRNAs) are believed to play important roles in mammalian spermatogenesis mainly because spermatogenesis is more or less disrupted when genes encoding key enzymes for miRNA biogenesis are mutated.
Jian Chen   +6 more
doaj   +1 more source

Antipsychotics and spermatogenesis, which is the impact?: A review of literature

open access: yesEuropean Psychiatry, 2023
Introduction Antipsychotics are among the most widely prescribed molecules in psychiatry. Their sexual side effects are frequent, generally underestimated by clinicians and subjectively poorly tolerated by patients.
H. Belhadga, Z. Elmaataoui, H. Kisra
doaj   +1 more source

The Prmt5-Vasa module is essential for spermatogenesis in Bombyx mori.

open access: yesPLoS Genetics, 2023
In lepidopteran insects, dichotomous spermatogenesis produces eupyrene spermatozoa, which are nucleated, and apyrene spermatozoa, which are anucleated.
Xu Yang   +12 more
doaj   +1 more source

Novel Gene Regulation in Normal and Abnormal Spermatogenesis

open access: yesCells, 2021
Spermatogenesis is a complex and dynamic process which is precisely controlledby genetic and epigenetic factors. With the development of new technologies (e.g., single-cell RNA sequencing), increasingly more regulatory genes related to spermatogenesis ...
Li Du   +7 more
doaj   +1 more source

Proteostasis regulated by testis-specific ribosomal protein RPL39L maintains mouse spermatogenesis

open access: yesiScience, 2021
Summary: Maintaining proteostasis is important for animal development. How proteostasis influences spermatogenesis that generates male gametes, spermatozoa, is not clear.
Qianxing Zou   +5 more
doaj   +1 more source

Irisin alleviates obesity-related spermatogenesis dysfunction via the regulation of the AMPKα signalling pathway

open access: yesReproductive Biology and Endocrinology, 2021
Background Infertility is a common complication in obese men. Oxidative stress and testicular apoptosis play critical roles in obesity-induced spermatogenesis dysfunction.
Yang Mu   +3 more
doaj   +1 more source

Evolution and spermatogenesis [PDF]

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2010
Sexual reproduction depends on the production of haploid gametes, and their fusion to form diploid zygotes. Here, we discuss sperm production and function in a molecular and functional evolutionary context, drawing predominantly from studies in model organisms (mice,Drosophila,Caenorhabditis elegans). We consider the mechanisms involved in establishing
Nina Bausek, Helen White-Cooper
openaire   +3 more sources

Microfilament‐Myosin II Regulates the Differentiation of Multinucleated Cysts into Oocytes and Influences Oocyte Developmental Potential in Mice

open access: yesAdvanced Science, EarlyView.
In this study, we provided new evidence identifying multinucleated cysts as precursors for oocyte differentiation. Within these cysts, organelles migrate and aggregate to form Balbiani body (B‐body) and establish early cellular polarity. Concurrently, excess nuclei are expelled, enabling cyst‐to‐oocyte differentiation. The microfilament‐myosin II plays
Rui Xu   +7 more
wiley   +1 more source

Epi-mutations for spermatogenic defects by maternal exposure to di(2-ethylhexyl) phthalate

open access: yeseLife, 2021
Exposure to environmental factors during fetal development may lead to epigenomic modifications in fetal germ cells, altering gene expression and promoting diseases in successive generations.
Yukiko Tando   +5 more
doaj   +1 more source

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