New and Emerging Treatments for Generalized Pustular Psoriasis: Focus on IL-36 Receptor Inhibitors
PharmaceuticsGeneralized Pustular Psoriasis (GPP) is a rare and severe subtype of psoriasis that significantly impacts patients’ quality of life. Until recently, no specific treatment modalities were available, and treatment for GPP followed the guidelines for the ...
João Vilaça +2 more
doaj +1 more source
Journal of the European Academy of Dermatology and Venereology, Volume 39, Issue 6, Page e544-e546, June 2025.
Qiaoxia Qian +21 more
wiley +1 more source
Clinical, Cosmetic and Investigational Dermatology, 2020 Egídio Freitas,1 Maria Alexandra Rodrigues,1 Tiago Torres1,2 1Department of Dermatology, Centro Hospitalar e Universitário do Porto, Porto, Portugal; 2Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Porto,
Freitas E, Rodrigues MA, Torres T
doaj
A Non-Interventional, Multicenter Study to Characterize the Socio-Demographics, Clinical Characteristics, and Management of Generalized Pustular Psoriasis Patients in Spain: IMPULSE Study [PDF]
Biologic treatment; Disease management; Generalized pustular psoriasisTratamiento biológico; Gestión de la enfermedad; Psoriasis pustulosa generalizadaTractament biològic; Gestió de la malaltia; Psoriasi pustulosa generalitzadaIntroduction: Generalized ...
Izu Belloso, Rosa +5 more
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New Therapies in the Biological Treatment of Psoriasis: A Review
AllergiesPsoriasis is a chronic inflammatory autoimmune disease primarily affecting the skin and, in some cases, the joints, and is characterized by erythematous, scaling lesions. Building up the doses has been conventional, but many patients will not obtain good
Mateusz Kamil Ożóg +4 more
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International Medical Case Reports JournalSi-Ning Wang,* Yi-Zhou Lu,* Yujuan Zhao, Wei Cao, Rui-Li Zhang Department of Dermatology, The Second Affiliated Hospital Nanjing Medical University, Nanjing Medical University, Nanjing, People’s Republic of China*These authors contributed ...
Wang SN, Lu YZ, Zhao Y, Cao W, Zhang RL
doaj
Diseases categorized as autoinflammatory keratinization diseases (AiKDs), and their pathologies and treatments [PDF]
Whole-exome and whole-genome sequencing have become widespread in approximately the last 15 years, and the predisposing factors and pathomechanisms of inflammatory keratinization diseases, which have been unknown for a long time, have gradually been ...
Akiyama, Masashi
core
IL-36RN gene: key insights into its role in pediatric pustular psoriasis pathogenesis and treatment [PDF]
Pediatric pustular psoriasis (PPP) is an autoimmune skin disease that seriously affects the physical and mental health of children. The IL-36RN (Interleukin-36 Receptor Antagonist) gene plays a key role in the pathogenesis of PPP.
Changcheng Hou +5 more
core +1 more source
Response to: letter to editor regarding “Spesolimab efficacy and safety in patients with moderate-to-severe palmoplantar pustulosis: a multicentre, double-blind, randomised, placebo-controlled, phase IIb, dose-finding study” [PDF]
No abstract ...
Burden, A. David
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