Results 151 to 160 of about 1,019 (188)
Some of the next articles are maybe not open access.

Treatment with spesolimab in patients with generalized pustular psoriasis: A review of real-world experience.

Clincal and Experimental Dermatology
Generalized pustular psoriasis (GPP) is a potentially life-threatening infrequent immune-mediated disease characterized by rapid-onset of erythematous plaques, sterile pustules, and systemic inflammation.
J. A. Cárdenas-de la Garza   +7 more
semanticscholar   +1 more source

Clinical Responses and Transcriptomic Analysis of Spesolimab in a Girl With Severe Dermatitis, Multiple Allergies and Metabolic Wasting Syndrome

Experimental Dermatology
Severe dermatitis, multiple allergies, and metabolic wasting syndrome (SAM) is a rare inherited disorder caused by biallelic loss‐of‐function mutations in the desmoglein‐1 (DSG1) or desmoplakin (DSP) genes.
Jinxiang Yang   +9 more
semanticscholar   +1 more source

Successful Treatment of Generalized Pustular Psoriasis With Spesolimab in Two Young Children.

Pediatric dermatology
Spesolimab is an IL-36 receptor monoclonal antibody antagonist approved for generalized pustular psoriasis in patients 12 years and older. While it has demonstrated promising results in this population, there is limited literature exploring spesolimab ...
Aisa Longnecker   +4 more
semanticscholar   +1 more source

Successful treatment of refractory and recurrent pyoderma gangrenosum with pustules and ulcers using spesolimab.

Clincal and Experimental Dermatology
We report a case of a patient with severe refractory pyoderma gangrenosum with ulcers and pustules that were unresponsive to long-term steroids, ciclosporin, intravenous immunoglobulin and tumour necrosis factor-α inhibitors.
Xinyue Pang   +5 more
semanticscholar   +1 more source

Spesolimab (Spevigo)

Canadian Journal of Health Technologies
Reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class. The assessments inform nonbinding recommendations that help guide the reimbursement decisions of Canada’s federal, provincial, and territorial governments, with the ...
openaire   +1 more source

P099 Spesolimab use in effective treatment of generalized pustular psoriasis: a case report

British Journal of Dermatology
The management of generalized pustular psoriasis (GPP) has been revolutionized by the development of the interleukin-36 receptor antagonist spesolimab.
S. Santhosh   +7 more
semanticscholar   +1 more source

Generalized pustular psoriasis treated with additional biologics after spesolimab: A case series from Japan.

Clincal and Experimental Dermatology
This case series from Japan describes three patients with generalized pustular psoriasis who required additional biologic therapies after initial treatment with spesolimab, due to persistent erythematous lesions.
Chiaki Sasaki   +7 more
semanticscholar   +1 more source

Spesolimab Treatment for the Prevention of Flares in People with Generalized Pustular Psoriasis (GPP): A Video Summary of the EFFISAYIL® 2 Study

Video Journal of Biomedicine
Prof. Morita presents the EFFISAYIL® 2 clinical trial, which investigated spesolimab treatment for the prevention of GPP flares.
A. Morita   +13 more
semanticscholar   +1 more source

Rapid Improvement in Refractory Acute Generalized Exanthematous Pustulosis With Spesolimab

JAMA Dermatology
This case report describes a woman in her 50s with rapid improvement in acute generalized exanthematous pustulosis symptoms after treatment with spesolimab.
Yijie, Xuan   +3 more
openaire   +2 more sources

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