Results 91 to 100 of about 86,647 (289)
, 1997 Prochaine séance SPF. In: Bulletin de la Société préhistorique française, tome 94, n°3, 1997.
core +2 more sources
Advanced Science, EarlyView.SMAD4 is identified as a guardian of 3D genome architecture in lung squamous cell carcinoma. Loss of SMAD4 unleashes EP300 at chromatin loop anchors, strengthening enhancer–promoter looping and H3K27ac at the SOX2 locus to drive aberrant SOX2 activation and tumor cell proliferation.
Qian Tang +33 more
wiley +1 more source
Silicic thermally stabilized p–i–n-photodiode
Технологія та конструювання в електронній апаратурі, 2006 A design of a silicon p–i–n photodiode crystal thermostabilized by a Peltier thermoelectric module is proposed and investigated. It is shown that such a design allows the noise current density to remain practically unchanged within the temperature range ...
Yu. G. Dobrovolsky
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Advanced Science, EarlyView.Radioresistance severely limits the efficacy of therapies for small cell lung cancer (SCLC). This study reveals a novel mechanism of resistance driven by the active suppression of pyroptosis. Specifically, the mTORC2 complex directly phosphorylates GSDME‐N and promotes its CUL4B‐mediated ubiquitination and proteasomal degradation.
Qing‐qing Xu +11 more
wiley +1 more source
, 1993 Séances de la SPF. In: Bulletin de la Société préhistorique française, tome 90, n°5, 1993.
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SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition
Advanced Science, EarlyView.Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo +14 more
wiley +1 more source
Cumhuriyet Science JournalUltraviolet (UV) radiation from the sun can cause significant damage to human skin, leading to both acute and chronic adverse effects. While commercial sunscreens provide protection, increasing consumer concerns about synthetic ingredients have driven ...
Yakup Budak
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Advanced Science, EarlyView.Exosomal miR‐146a‐5p is identified as a pivotal regulator in steroid‐induced osteonecrosis. Its reduction activates NF‐κB signaling, compromises mitophagy, and disrupts mitochondrial bioenergetics, resulting in autophagic disequilibrium. Engineered exosomes delivering miR‐146a‐5p reinstate mitochondrial function, augment oxidative phosphorylation and ...
Zehui Lv +13 more
wiley +1 more source
Fiber reinforced refractory castables for SPF toolings [PDF]
, 2008 International audienceFiber reinforced refractory castable (FRRC) is an emerging material solution to manufacture SPF tools for forming titanium alloy sheets. Indeed, FRRC are able to conserve good mechanical properties up to 900 degrees C.
Bernhart, Gérard +5 more
core +1 more source
Antioxidant activity and sun screening effects of Bacterial melanin
Journal of BioScience and Biotechnology, 2020 The present work was delineated to formulate and evaluate antioxidant and photoprotective properties of melanin produced by Pseudomonas mosseliistrain STSGRDS1 against the purchased fungal melanin STSGRDM1 as standard. Initially,
Sharmila D.Srimathi +5 more
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