Results 71 to 80 of about 86,647 (289)

BIN1 and ALDH1B1 Deficiency in Colonic Smooth Muscle Drives Mitochondrial Dysfunction and Fibrosis in Slow‐Transit Constipation

open access: yesAdvanced Science, EarlyView.
Slow‐transit constipation (STC) is a disabling motility disorder with unclear smooth‐muscle mechanisms. Spatial proteomic analysis of STC patient colon reveals both the central pathogenic role of smooth muscle cells (SMCs) in STC and novel regulators of intestinal motility, BIN1 and ALDH1B1.
Jianbo Liu   +10 more
wiley   +1 more source

Centenaire de la SPF [PDF]

open access: yes, 2003
Centenaire de la SPF. In: Bulletin de la Société préhistorique française, tome 100, n°4, 2003. pp.

core   +2 more sources

Astrocytic LMP2 Coordinates NF‐κB and TGF‐β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion

open access: yesAdvanced Science, EarlyView.
ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao   +7 more
wiley   +1 more source

Degradation characteristics of SPF/SPS biocomposites [PDF]

open access: yes, 2014
In this work, sugar palm fibres (SPF) were used as a biodegradable reinforcement. SPF were incorporated into sugar palm starch (SPS) plasticised with glycerol using the compression molding process. Then the SPS and SPF/SPS biocomposites were submitted to
Salit, Mohd Sapuan   +7 more
core  

Première séance SPF 1998 [PDF]

open access: yes, 1997
Première séance SPF 1998. In: Bulletin de la Société préhistorique française, tome 94, n°4, 1997.

core   +2 more sources

A Randomized Study to Determine the Sun Protection Factor of Natural Pterostilbene from Pterocarpus Marsupium

open access: yesCosmetics, 2020
Ultraviolet (UV) rays and its harmful effects have always been a concern to skin health. Sunscreen and sunblock prevent the harmful effects of UV radiation on the skin.
Muhammed Majeed   +6 more
doaj   +1 more source

Mitochondrial SLC25A46 Rewires Fatty Acid Oxidation to Promote Cell Proliferation and Ferroptosis Evasion in Ovarian Cancer by Stabilizing CACT

open access: yesAdvanced Science, EarlyView.
Mitochondrial SLC25A46 is upregulated in ovarian cancer (OC) and correlates with poor prognosis. SLC25A46 stabilizes CACT to activate fatty acid oxidation, increasing ATP and NADPH production to drive cell proliferation and ferroptosis evasion. SLC25A46 silencing sensitizes OC cells to ferroptosis and carboplatin, offering a promising therapeutic ...
Yunge Gao   +9 more
wiley   +1 more source

Dernière séance SPF 1997 [PDF]

open access: yes, 1997
Dernière séance SPF 1997. In: Bulletin de la Société préhistorique française, tome 94, n°4, 1997.

core  

UV-absorbing mycosporin-like compounds in some macroalgae of the Persian Gulf and its potential application in the formulation of sunscreens [PDF]

open access: yesبوم‌شناسی آبزیان, 2020
Despite major advances in chemical synthesis, the use of natural species, especially algae, is still of interest in pharmaceutical research due to its wide range of biologically active compounds.
Maryam Kokabi   +3 more
doaj  

Optimization of B Cell Responses in Human Immune System Mice Through Organoid Based Screening

open access: yesAdvanced Science, EarlyView.
Human immune system (HIS) mice show limited B cell responses to immunization. Using HIS mouse spleen organoids, this study identifies cytokine combinations and innate immune signals that drive human B cell expansion, differentiation, and class‐switch. Applying these signals in vivo through temporal separation enables antigen‐specific IgG responses and ...
Haiqiao Sun   +6 more
wiley   +1 more source

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