Results 61 to 70 of about 73,826 (252)

Dosimeters of power luminosity of the ultraviolet radiation "Tenzor"

Технологія та конструювання в електронній апаратурі, 2006
A group of dosimeters for ultraviolet and visible radiation — “Tenzor‑51”, “Tenzor‑52”, and “Tenzor‑53” — has been developed in accordance with the requirements of current regulatory documentation. The basic relative measurement error of these dosimeters
V. K. Butenko, Yu. G. Dobrovolskiy, B. G. Shabashkevich, V. G. Yurev, B. G. Shabashkevich   +4 more
doaj  

Performance Analysis of Air-to-Water Heat Pump in Latvian Climate Conditions

Environmental and Climate Technologies, 2014
Strategy of the European Union in efficient energy usage demands to have a higher proportion of renewable energy in the energy market. Since heat pumps are considered to be one of the most efficient heating and cooling systems, they will play an ...
Kazjonovs Janis, Sipkevics Andrejs, Jakovics Andris, Dancigs Andris, Bajare Diana, Dancigs Leonards   +5 more
doaj   +1 more source

Materials‐Guided Gene‐Ionizable Lipid Nanoparticles to Reverse Iron‐Associated Immune Resistance in Renal Cancer

Advanced Science, EarlyView.
ABSTRACT Iron overload is a common metabolic disturbance in cancer and contributes to poor outcomes in renal cell carcinoma (RCC), yet its effects on the tumour immune microenvironment remain unclear. Here we identify a previously unrecognized immunosuppressive axis in which iron overload downregulates the palmitoyltransferase ZDHHC12 in CD8+ T cells ...
Xin Jin, Yulong Hong, Chengliang Yin, Wanyang Guo, Yaxuan Wang, Ruijiang Zeng, Ruilin Liu, Zexian Ding, Xinlin Liu, Shangqing Ren, Qiyang Liang, Yaohui Wang, Xu Zhang, João Conde, Yuan Li, Xin Ma, Liangyou Gu   +16 more
wiley   +1 more source

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin, Qiong Li, Xuemei Xu, Yuhan Wu, Yin Zhu, Jieqiong Wu, Yuan Fang, Qiubei Chen, Shuyang Wang, Jiang Yu, Yaping Ye, Hongli Jiao   +11 more
wiley   +1 more source

Silicic thermally stabilized p–i–n-photodiode

Технологія та конструювання в електронній апаратурі, 2006
A design of a silicon p–i–n photodiode crystal thermostabilized by a Peltier thermoelectric module is proposed and investigated. It is shown that such a design allows the noise current density to remain practically unchanged within the temperature range ...
Yu. G. Dobrovolsky
doaj  

Targeting ANGPTL3 and IL‐33/ST2 Ameliorates Diabetic Kidney Disease by Reducing Lipotoxicity, Alleviating Inflammation and Inhibiting Fibrosis

Advanced Science, EarlyView.
Dual targeting of ANGPTL3 and IL‐33/ST2 attenuates diabetic kidney disease by reprogramming lipid–inflammatory crosstalk. This strategy reduces renal lipotoxicity, suppresses inflammatory activation, and limits fibrotic remodeling, thereby preserving kidney structure and function and highlighting a mechanism‐guided therapeutic approach for metabolic ...
Zhuojin Li, Zhonglian Cao, Rongrui Zhou, Xu Cheng, Xiaozhi Hu, Shuwen Xu, Zihan Dou, Ling Du, Dianwen Ju   +8 more
wiley   +1 more source

Bandgap‐Engineered PtxTey:Ag2Te Composite Quantum Dots Enable Programmable NIR‐II Imaging and Photothermal‐Immune Synergistic Therapy

Advanced Science, EarlyView.
A bandgap‐engineered PtxTey:Ag2Te quantum dot platform enables tunable NIR‐IIb emission for deep‐tissue imaging and mild photothermal therapy. Conjugation with αPD‐L1 confers dual tumor targeting and real‐time monitoring of PD‐L1 dynamics. Mild photothermal modulation induces immune reprogramming, enhancing checkpoint blockade efficacy and achieving ...
Jing Liu, Rui Xu, Quan Wu, Tian‐Xin Xiao, Lai‐Xi Zhao, Lei Sun, Ya‐Wen Zheng, Liang Dong, Zhi‐Quan Tian, Haibo Wang   +9 more
wiley   +1 more source

Comparative Physicochemical Properties and Photoprotective Efficacy of Homemade and Commercial Herbal Sunscreens

Cumhuriyet Science Journal
Ultraviolet (UV) radiation from the sun can cause significant damage to human skin, leading to both acute and chronic adverse effects. While commercial sunscreens provide protection, increasing consumer concerns about synthetic ingredients have driven ...
Yakup Budak
doaj   +1 more source

SIRT6‐Mediated Deacetylation of ATF3 Promotes Silica‐Induced Lung Fibrosis by Enhancing its Nuclear Import via Binding to Importin α

Advanced Science, EarlyView.
SIRT6‐mediated ATF3 acetylation drives MGARP transcription and mitochondrial dysfunction in macrophages, promoting macrophage senescence and pulmonary fibrosis. Mechanistically, HSP70/Importin α competitively binds to ATF3, modulating its nuclear translocation.
Demin Cheng, Wenxia Bu, Fengxu Wang, Yueyuan Jin, Rongzhu Liu, Rui Zhao, Xuehai Wang, Mengna Jiang, Jinping Shen, Xinhang Cheng, Zuming Chen, Li Zhu, Jinlong Li, Zhenzhong Ge, Shichen Miao, Haotian Xu, Xiaoyu Zhou, Dongming Wang, Xinyuan Zhao   +18 more
wiley   +1 more source

Antioxidant activity and sun screening effects of Bacterial melanin

Journal of BioScience and Biotechnology, 2020
The present work was delineated to formulate and evaluate antioxidant and photoprotective properties of melanin produced by Pseudomonas mosseliistrain STSGRDS1 against the purchased fungal melanin STSGRDM1 as standard. Initially,
Sharmila D.Srimathi, Trisha P.A.Mary, Arya R Krishna, Jayaprabha C., Swathy Krishna J., Suganthi Ramasamy   +5 more
doaj