Results 171 to 180 of about 71,184 (285)

NIR Ratiometric Fluorescent Antibody‐Drug Conjugate for Metastatic Ovarian Cancer Theranostics and Treatment Response Monitoring

Advanced Science, EarlyView.
In vivo optical imaging enhances antibody‐drug conjugate (ADC) optimization by enabling real‐time monitoring of stimulus‐responsive drug behavior. We report n501‐CYMMAF, a ratiometric theranostic with strong target affinity and low‐dose efficacy for ovarian metastasis.
Cheng Li, Zezhong Yu, Tao Pu, Yanling Wu, Gang Wang, Youhua Xie, Tianlei Ying, Zhenlin Yang, Yibing Shi   +8 more
wiley   +1 more source

Isolation, Genomic Characterization, and Pathogenicity of a Novel Duck Orbivirus Genetically Similar to Corriparta Virus in China. [PDF]

Transbound Emerg Dis
Liu L, Guo X, Hu F, Lu X, Lv Y, Wang J, Ma Q, Tong Y, Tian F, Qian Y, Jung YS, Ma X, Huang B, Li Y, Yu K.   +14 more
europepmc   +1 more source

Model PembeLajaran Project Based Learning Terhadap Motivasi Dan Kemampuan Berpikir Kritis Peserta Didik UPT SPF SD Inpres Tamalanrea 2 Makassar

Andi Wirahandayani, Muhammad Yunus, Sundari Hamid   +2 more
openalex   +2 more sources

Targeting IL27RA Enhances Immunotherapy in Triple‐Negative Breast Cancer by Modulating Tumor Cells and the Tumor Microenvironment

Advanced Science, EarlyView.
IL27RA upregulation drives immune evasion in TNBC by suppressing MHC‐I expression and reprogramming T/NK‐cell states, establishing an immune‐excluded tumor phenotype. Targeting this epithelial‐intrinsic IL27RA–PI3K/AKT axis offers a promising strategy to overcome immunotherapy resistance.
Jiachi Xu, Qian Long, Meirong Zhou, Qitong Chen, Jing Peng, Qingchun Liang, Danhua Zhang, Hui Zhou, Wenjun Yi   +8 more
wiley   +1 more source

Experiences and Perceptions of Functional Recovery in Late-Life Depression: A Qualitative Study. [PDF]

Int J Ment Health Nurs
Cardol S, Timmerman I, Matthews J, Lucassen P, Collard R.   +4 more
europepmc   +1 more source

Alternative Pathway for Methyl Supply through the Coupling of SHMT1 and PEMT to Maintain Astrocytic Homeostasis in Parkinson's Disease

Advanced Science, EarlyView.
In Parkinson's disease, SHMT1 downregulation disrupts its interaction with PEMT in astrocytes, reducing SAM levels. This leads to H3K4me1 hypomethylation and decreased Slc1a2/Glul expression, ultimately exacerbating neuroexcitotoxicity and dopaminergic neuron loss.
Yue‐Han Chen, Rong‐Xin Zhu, Nuo‐Xi Zhang, Ting‐Ting Sun, Xi‐Wei Zhang, Yu‐Jie Zhao, Ben‐Yu He, Hang Yao, Ren‐Hong Du, Lei Cao, Wen‐Bin Zhang, Wei‐Guo Liu, Yun Cai, Cong Wang, Gang Hu, Yao Wei, Yang Liu, Ming Lu   +17 more
wiley   +1 more source

Filters or Holt Winters Technique to Improve the SPF Forecasts for USA Inflation Rate?

, 2013
Mihaela Bratu
openalex   +1 more source

Dynamic changes in the gut microbiota of SPF Bama piglets during breast and formula feeding [PDF]

Chengcheng Zhang, Zhengjiang Liu, Huan Yu, Yuanyuan Shen, Lu Lu, Fanli Kong, Wei Sun, Xiaoyuan Wei, Long Jin, Liangpeng Ge, Bo Zeng   +10 more
openalex   +1 more source

Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles

Advanced Science, EarlyView.
A schematic diagram of the mechanism where small extracellular vesicles mediate the enhancement of heterotopic wound healing by radial extracorporeal shockwave stimulation at a proximal tibial osteotomy site. ABSTRACT Wound healing represents a complex biological process necessitating innovative therapeutic approaches, particularly for chronic wounds ...
Xiaoping Xie, Songqi Bi, Bang Su, Rongqi Zhou, Xudong Li, Zhixing Yan, Xiaoyang Zhou, Fanxu Wang, Tiecheng Yu   +8 more
wiley   +1 more source

Side-polished fiber evanescent wave quartz-enhanced photoacoustic spectroscopy employing dielectric coatings for evanescent field enhancement. [PDF]

Photoacoustics
Twomey CF, Biagi G, Ruth AA, Ali F, Di Falco A, O'Faolain L, Walsh AJ.   +6 more
europepmc   +1 more source