Results 231 to 240 of about 2,109,763 (264)

IGF2BP3 promotes glycolysis of osteosarcoma stem cells by reading RNA m⁶A to stabilize ENO1 and promote malignant biological behavior of osteosarcoma. [PDF]

Cell Biol Toxicol
Zhang B, Ren X, Wang B, Wang Y, Zhang D, Meng F.   +5 more
europepmc   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

A miR-124-3p/PKC-δ Regulatory Axis Restrains Bladder Cancer Growth and Malignant Progression. [PDF]

In Vivo
Kuo YC, Wang HY, Liao TL, Weng YS, Ko YC, Su LT, Hsu KW.   +6 more
europepmc   +1 more source

Validation of a Cellular Imaging‐Based Method as a Potential Biomarker for SPG4 Hereditary Spastic Paraplegia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini, Valerio Licursi, Gianmarco Dalla Zanna, Flavio Dal Canto, Melissa Barghigiani, Nunzio Setola, Salvatore Rossi, Antonio Funcis, Filippo M. Santorelli, Gabriella Silvestri, Carlo Casali, Francesca Sardina, Cinzia Rinaldo   +12 more
wiley   +1 more source

Hedgehog/GLI1 regulates EMT and cancer stem cell properties via the GLI1-Bmi1 axis in diffuse large B-cell lymphoma. [PDF]

Sci Rep
Xiao H, Li C, Han Y, Gao J, Xu W, Xin P, Zhu X.   +6 more
europepmc   +1 more source

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali, Priyanka Menon, Halil I. Corbali, Ram Jagannathan, Allan I. Levey   +4 more
wiley   +1 more source

C3G Downregulation Enhances Stemness in Glioblastoma Cells by Promoting PKM2 Upregulation. [PDF]

Int J Biol Sci
Cueto-Remacha M, Manzano S, Iniesta-González M, Mancebo J, Martin-Serna P, Palao N, Baquero C, López-Pastor AR, Peralbo-Avilés C, Gutierrez-Uzquiza A, Cuesta ÁM, Bragado P, Guerrero C, Porras A.   +13 more
europepmc   +1 more source

Uncovering the mechanism of DCLK3 in colorectal cancer progression through WGCNA and machine learning. [PDF]

BMC Cancer
Yang L, Han Y, Ji J, Wang Y, Yang F, Li W, Guo X.   +6 more
europepmc   +1 more source

β-Propeller structure of the CJ1041C protein from Campylobacter jejuni and its interaction with Ca²⁺ ions. [PDF]

Sci Rep
Park MA, Yoon SI.
europepmc   +1 more source

PTEN-AKT2 regulates mixed lineage liver cancer development and sensitizes cancer cells to TGFβ treatment. [PDF]

Oncogene
Tang Q, Slarve I, Chen J, Zeng N, Gu Y, He L, Hu S, Alhousari D, Xu Z, Hua B, Zhang G, Nguyen P, Alba M, Bharadwaj A, Lee J, Kreimer S, Xu J, Ji B, Lu SC, Van Eyk J, Chopra S, Kanel G, Yuan L, Stiles BL.   +23 more
europepmc   +1 more source