Results 61 to 70 of about 458,908 (294)
Many drugs have a propensity for agglomeration, resulting in poor flowability. Spherical crystallization can be used to improve product properties including flowability and particle size.
Fei Li +8 more
core +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Microcellular polymer foams are a kind of advanced polymeric foams that show light weight and enhanced thermally insulating performance compared with traditional polymer foams.
Aimin Zhang +5 more
doaj +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Crystallization behavior of poly(lactide)/poly(β-hydroxybutyrate)/talc composites. [PDF]
The authors thank Dr. Patrice Lefrançois (CNAM) for SEM observations. They are also grateful to Pr. Jack R. Plimmer USDA, Agricultural Research Service, USA for his discussions during this work.The morphology and miscibility of commercial poly(lactide ...
TRI, Phuong Nguyen +3 more
core +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Spherical crystallization scale-up
Sferična kristalizacija metoda je kristalizacije koja rezultira izravnim nastankom sferičnih kristala poboljšanih fizikalno – kemijskih svojstava čime se olakšava proces proizvodnje lijekova.
Crnac, Lana
core +2 more sources
Novel agglomerated crystallization techniques, i.e., neutralization and solvent change, methods, were devised in order to design phenytoin (antiepileptic), crystals so as to be directly compounded during their formulation.
Yoshiaki Kawashima +3 more
doaj +1 more source
Continuous Spherical Crystallization of Albuterol Sulfate with Solvent Recycle System
Spherical crystallization enables the direct preparation of crystal agglomerates of active pharmaceutical ingredients (APIs) with improved crystal handling properties.
Kohei Tahara (1516240) +2 more
core +1 more source
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source

