Brain endothelial spheroids and cortical organoids reveal the impact of Toxoplasma gondii lineage and host-phagocyte-pathogen interactions on colonization. [PDF]
Rodriguez ME +4 more
europepmc +1 more source
A Soft Microrobot for Single‐Cell Transport, Spheroid Assembly, and Dual‐Mode Drug Screening
A soft, untethered hydrogel microrobot enables precise single‐cell delivery, self‐assembly into 3D spheroids, and real‐time thermal actuation. Driven by light‐induced convection and embedded with gold nanorods and temperature sensors, the microrobot guides cells, modulates local microenvironments, and supports drug testing.
Philipp Harder +3 more
wiley +1 more source
Generation of uniform-sized spheroids as 3D cancer models using simple and scalable PDMS-based microwell devices. [PDF]
Goli S +8 more
europepmc +1 more source
Artificial Symbiosis for Bulk Production of Bacterial Cellulose Composites
Co‐cultivation of the cellulose‐producing bacterium with the microalga enables bulk formation of bacterial cellulose under static incubation, with photosynthetically active oxygen‐generating sites throughout the medium. This symbiotic platform supports 3D cellulosic constructs with geometries dictated by the vessel shape.
Kui Yu +7 more
wiley +1 more source
Optimising the method to develop spheroids from MDA-MB-468 human triple negative breast cancer cells. [PDF]
Mohamedahmed SM +4 more
europepmc +1 more source
A novel immunotherapeutic strategy combines injectable, adjuvant‐loaded hydrogels with externally controlled histotripsy to create immune‐priming sites within tumors. This approach generates millimeter‐sized immune‐activated lesions with flexible, patient‐tailored treatment scheduling, enabling precise immune activation through tumor ablation‐mediated ...
Sung Hoon Kim +9 more
wiley +1 more source
A single-cell derived spheroid approach to dissect intratumoural heterogeneity in colorectal cancer: cell lines show changes in proteomes and therapeutic response to 5-FU. [PDF]
Radloff HS +6 more
europepmc +1 more source
Promising Applications of Tumor Spheroids and Organoids for Personalized Medicine [PDF]
Zarema Gilazieva +4 more
openalex +1 more source
Multiphysics‐Driven Assembly of Biomimetic Vesicles
Artificial extracellular vesicles, derived from cell membranes, are manufactured using a multiphysics‐integrated microfluidic platform that combines nanoknife membrane rupture, herringbone chaotic mixing, and acoustothermal modulation. This standardizable workflow enables the predictable control of vesicle formation and therapeutic loading, while ...
Timofei Solodko +16 more
wiley +1 more source
Dynamic Optical Lattices Through Conducting Polymer‐Gated Confinement
The conducting polymer gate is incorporated into organic dielectric lattices to control the dynamic switching of nonlocal Mie resonances in the visible/NIR regions. The “closed gate” from oxidized PEDOT confines the light within dielectric nanocylinders and activates nonlocal Mie resonances, while the “opened gate” from reduced PEDOT facilitates ...
Dongqing Lin +3 more
wiley +1 more source

