Results 221 to 230 of about 130,558 (351)

Electrical Impedance Spectroscopy for Microtissue Spheroid Analysis in Hanging-Drop Networks

, 2016
Yannick R. F. Schmid, Sebastian C. Bürgel, Patrick M. Misun, Andreas Hierlemann, Olivier Frey   +4 more
openalex   +2 more sources

Nanomaterial‐Based Muscle Cell/Neural Tissue Biohybrid Robots: From Actuation to Biomedical Applications

Advanced Robotics Research, EarlyView.
Muscle cell‐based biohybrid robot using nanomaterials for function enhancement and neural function for biomedical applications. Biohybrid robotics, an emerging field combining biological tissues with artificial systems, has made significant progress in developing various biohybrid constructs, including muscle‐cell‐driven biorobots and microbots.
Minkyu Shin, Sangeun Lee, Su Ryon Shin, Jin‐Ha Choi, Jeong‐Woo Choi   +4 more
wiley   +1 more source

Spheroid Sheets: A Scalable Platform for Producing Tissue Membrane Constructs. [PDF]

Bio Protoc
Le QB, Ezhilarasu H, Chan WW, Choudhury D.   +3 more
europepmc   +1 more source

EIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial Cancer

Advanced Science, EarlyView.
This schematic illustrates the mechanism of a senolytic strategy in endometrial cancer. EIF1AX facilitates the incorporation of DDX21 into nucleolar condensates, an event that suppresses rDNA transcription and induces cellular senescence. The compound 2,5‐MeC exploits this pathway by promoting EIF1AX nucleolar translocation and condensate formation ...
Chengyu Lv, Zihang Lin, Jiandong Sun, Yuhong Ye, Qibin Wu, Liangzhi Cai, Dabin Liu, Pengming Sun, Shie Wang   +8 more
wiley   +1 more source

Synergistic anti-tumor effects of novel two-domain soluble Fms-like tyrosine kinase-1 and paclitaxel on three-dimensional breast cancer models: implications for targeted therapy. [PDF]

J Transl Med
Mutahar AZI, Dayal R, Salimath BP.
europepmc   +1 more source

Dystrophic Axonal Formation (Spheroid Body) in Central Neurocytoma —Case Report—

, 1993
Ahmed Diraz, Mitsuhiro Tada, Yutaka Sawamura, Junichi Murata, Toshimitsu Aida, Hiroshi Abe, Kazuo Nagashima   +6 more
openalex   +2 more sources

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

Advanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li, Chenyang Meng, Guangcong Shen, Yueying Shan, Junjin Wang, Diliyaer Abudukeremu, Rui Zhao, Bo Ni, Chao Xu, Xiaofan Guo, Jun Yu, Kaiyuan Wang, Shengyu Yang, YunZhan Li, Yongjie Xie, Tianxing Zhou, Jihui Hao, Xiuchao Wang   +17 more
wiley   +1 more source

Systematic investigation of the effects of neural stem cell spheroid size and density on fate specification in 3D culture.

J Mater Chem B
Duquette R, Salazar SP, Wang ZZ, Sohrabi A, Seidlits SK.   +4 more
europepmc   +1 more source

Visualization, Data Extraction, and Multiparametric Analysis of 3D Pancreatic and Colorectal Cancer Cell Lines for High-Throughput Screening. [PDF]

Biomedicines
Trofimov MA, Bulatov IP, Lavrinenko VS, Popov VE, Petrova VS, Bukatin AS, Tyazhelnikov SF.   +6 more
europepmc   +1 more source

A Patient‐Derived Organ‐on‐Chip Platform for Modeling the Tumor Microenvironment and Drug Responses in Pancreatic Cancer

Advanced Science, EarlyView.
Researchers have developed a patient‐derived organ‐on‐a‐chip model for pancreatic cancer by integrating cancer cells with supportive stromal and immune cells inside a microfluidic device. This system mimics the tumor microenvironment, enabling personalized testing of chemotherapy and immunotherapy, and offering new insights into how targeting ...
Darbaz Adnan, Natan Roberto de Barros, Luca S. Santovito, Xuhong Cheng, Kristi M. Lawrence, Mariah K. Barnett, Martine D. Boetto, Neal Mehta, Ajaypal Singh, Lin Cheng, Xiangsheng Huang, Faraz Bishehsari   +11 more
wiley   +1 more source