Results 81 to 90 of about 48,095 (292)

Use of isotopically labeled substrates reveals kinetic differences between human and bacterial serine palmitoyltransferase

open access: yesJournal of Lipid Research, 2019
Isotope labels are frequently used tools to track metabolites through complex biochemical pathways and to discern the mechanisms of enzyme-catalyzed reactions.
Peter J. Harrison   +7 more
doaj   +1 more source

A Meal Rich in Palm Oil or Butter Modifies the Sphingolipid Profile of Postprandial Triglyceride-Rich Lipoproteins From Type 2 Diabetic Patients [PDF]

open access: gold, 2022
Marie‐Caroline Michalski   +6 more
openalex   +1 more source

Sphingolipid trafficking — sorted out?

open access: yesTrends in Cell Biology, 1992
Studies of intracellular membrane traffic have traditionally focused on the protein components of membranes, but what about lipids? Recent findings have drawn attention to the transport of one type of lipid, the sphingolipids. Their unique physical properties may allow them to aggregate into microdomains in membranes that concentrate sphingolipids into
van Meer, G., Burger, K.N.J.
openaire   +3 more sources

Fasting and Refeeding Mediated Phospholipid Remodeling Plays an Important Role in Improving Meat Quality of Aged Laying Hens

open access: yesAnimal Research and One Health, EarlyView.
ABSTRACT This study explored fasting‐induced physiological remodeling effects on meat quality in aged laying hens. Fasting for 15 days (F15) significantly reduced abdominal fat, intermuscular fat width, subcutaneous fat thickness, and liver index versus pre‐fasting (F0) (p < 0.05), which recovered post‐refeeding.
Xiaoran Zhang   +8 more
wiley   +1 more source

Sphingolipids in Major Depression

open access: yesNeurosignals, 2015
Major depression is one of the most common and severe diseases affecting the world's population. However, the pathogenesis of the disease remains inadequately defined. Previously, a lack of monoaminergic neurotransmitters was the focus of pathophysiological concepts; however, recent concepts focus on a alteration of neurogenesis in the hippocampus ...
Jernigan, Peter L.   +6 more
openaire   +4 more sources

Fresh insights into the light‐induced pineal gland circadian rhythm transmission mechanism derived from mRNA and miRNA profiling

open access: yesAnimal Research and One Health, EarlyView.
Mechanisms of light in regulating the chick pineal clock. Abstract The circadian clock significantly impacts animal health and productivity, with light playing a crucial role in regulating circadian rhythms. However, the mechanisms behind light‐induced circadian transmission remain unclear, particularly in light‐sensitive avian species.
Yunlei Li   +10 more
wiley   +1 more source

Characterization of free endogenous C14 and C16 sphingoid bases from Drosophila melanogaster

open access: yesJournal of Lipid Research, 2004
Sphingolipid metabolites function as signaling molecules in mammalian cells, influencing cell proliferation, migration, and death. Recently, sphingolipid signaling has been implicated in the regulation of developmental processes in Drosophila ...
Henrik Fyrst   +3 more
doaj   +1 more source

A Sphingolipid Elicitor-Inducible Mitogen-Activated Protein Kinase Is Regulated by the Small GTPase OsRac1 and Heterotrimeric G-Protein in Rice  [PDF]

open access: bronze, 2005
Damien Lieberherr   +5 more
openalex   +1 more source

Molecular stratification of antiphospholipid syndrome through integrative analysis of the whole‐blood RNA transcriptome

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Antiphospholipid syndrome (APS) is a thrombo‐inflammatory disorder characterized by clinical and mechanistic heterogeneity that complicates early diagnosis and hinders targeted treatment. We aimed to identify distinct molecular endotypes among antiphospholipid antibody (aPL)‐positive patients using whole‐blood transcriptomics.
Amala Ambati   +13 more
wiley   +1 more source

Sphingosine-1-phosphate lyase expression in embryonic and adult murine tissues

open access: yesJournal of Lipid Research, 2012
Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid involved in immunity, inflammation, angiogenesis, and cancer. S1P lyase (SPL) is the essential enzyme responsible for S1P degradation. SPL augments apoptosis and is down-regulated in cancer.
Alexander D. Borowsky   +12 more
doaj   +1 more source

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