Results 81 to 90 of about 68,956 (338)
Advanced Healthcare Materials, EarlyView.Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee +9 more
wiley +1 more source
Removal of the Sphingolipid impurity from preparations of yeast phosphatidyl inositol
Journal of Lipid Research, 1967 A complex sphingolipid containing inositol and mannose, present in lipid extracted from toluene-autolyzed baker's yeast, was eluted from silicic acid columns immediately after phosphatidyl inositol, and was the main nitrogenous impurity in crude ...
William E. Trevelyan
doaj +1 more source
Strong Alterations in the Sphingolipid Profile of Chickens Fed a Dose of Fumonisins Considered Safe
Toxins, 2021 Fumonisins (FB) are mycotoxins known to exert most of their toxicity by blocking ceramide synthase, resulting in disruption of sphingolipid metabolism.
Didier Tardieu +3 more
doaj +1 more source
Regulation of TORC2 function and localization by Rab5 GTPases in Saccharomyces cerevisiae. [PDF]
, 2019 The evolutionarily conserved Target of Rapamycin (TOR) complex-2 (TORC2) is an essential regulator of plasma membrane homeostasis in budding yeast (Saccharomyces cerevisiae).
Locke, Melissa N, Thorner, Jeremy
core +1 more source
Dysregulated Choline, Methionine, and Aromatic Amino Acid Metabolism in Patients with Wilson Disease: Exploratory Metabolomic Profiling and Implications for Hepatic and Neurologic Phenotypes. [PDF]
, 2019 Wilson disease (WD) is a genetic copper overload condition characterized by hepatic and neuropsychiatric symptoms with a not well-understood pathogenesis.
Czlonkowska, Anna +6 more
core +2 more sources
Sphingolipids in colon cancer [PDF]
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2014 Colorectal cancer is one of the major causes of death in the western world. Despite increasing knowledge of the molecular signaling pathways implicated in colon cancer, therapeutic outcomes are still only moderately successful. Sphingolipids, a family of N-acyl linked lipids, have not only structural functions but are also implicated in important ...
Yusuf A. Hannun +4 more
openaire +3 more sources
Advanced Healthcare Materials, EarlyView.Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz +2 more
wiley +1 more source
Toxins, 2022 Alteration of sphingolipid synthesis is a key event in fumonisins toxicity, but only limited data have been reported regarding the effects of fumonisins on the sphingolipidome.
Philippe Guerre +3 more
doaj +1 more source
Sphingolipid metabolic flow controls phosphoinositide turnover at the trans Golgi network [PDF]
, 2017 Sphingolipids are membrane lipids, which are globally required for eukaryotic life. Sphingolipid composition varies among endomembranes with pre- and post-Golgi compartments being poor and rich in sphingolipids, respectively.
Alberto Luini +19 more
core +3 more sources
Use of Fluorescent Sphingolipid Precursors for Biophysical Studies of Sphingolipids [PDF]
Biophysical Journal, 2012 Sphingolipids are one of the major components of cell membranes and also play critical roles in cell signaling. Many studies of disrupted cells have expanded our understanding of sphingolipid metabolism and function. Nonetheless, investigations of dynamic sphingolipid events, such as trafficking, diffusion, and organization in cell membranes, require ...
Mary L. Kraft, Raehyun Kim, Kaiyan Lou
openaire +2 more sources