Results 171 to 180 of about 1,668,348 (220)

Reconstruction of Molecular Interaction Patterns from Endolysosomes in Ceramide-Depleted Cells. [PDF]

Nano Lett
Feng Y, Gärber F, Spedalieri C, Werner S, Pratsch C, Arenz C, Seifert S, Kneipp J.   +7 more
europepmc   +1 more source

Congenital Disorders of Glycosphingolipid Biosynthesis: Ultrarare Severe Syndromes or Relatively Frequent Mild Neurocognitive Illnesses? [PDF]

Biomedicines
Montavoci L, Dei Cas M, Penati S, Trinchera M.   +3 more
europepmc   +1 more source

Intestinal bacteria trigger a hibernation-like state in homotherms via the gut-brain axis. [PDF]

NPJ Biofilms Microbiomes
Bao Z, Guo C, Chen Y, Lei T, Peng H, Zhang H, Zhang X, Ban Y, Qi D, Feng J, Xiang Z.   +10 more
europepmc   +1 more source

Sphingolipid metabolism-related genes B4GALNT1 and CERS4 as prognostic biomarkers in lung adenocarcinoma. [PDF]

PLoS One
Jeon J, Kang J, Park JH, Lee JH, Kim DE, Park WJ, Kim S.   +6 more
europepmc   +1 more source

Genetic Architecture of Synaptic Failure in Dementia with Lewy Bodies: From α-Synuclein Proteoforms to GBA1-Mediated Plasticity Deficits. [PDF]

Genes (Basel)
Bougea A.
europepmc   +1 more source

Ceramide kinase/ceramide 1-phosphate signaling regulates LC3B expression and autophagosome formation. [PDF]

J Lipid Res
Funou H, Arai N, Nakajima S, Kadowaki R, Nakamaura K, Uzu M, Honda T, Nakamura H.   +7 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Activator proteins and topology of lysosomal sphingolipid catabolism

Lipids and Lipid Metabolism, 1992
The lysosomal degradation of several sphingolipids by acid hydrolases is dependent on small non-enzymic cofactors, called sphingolipid activator proteins some of which have been identified as sphingolipid binding proteins. This review summarizes the information available on the structure, function, biosynthesis, gene organization and pathobiochemistry ...
Konrad Sandhoff, W Fürst
exaly   +3 more sources

Sphingolipid hydrolase activator proteins and their precursors

Biochemical and Biophysical Research Communications, 1989
Activator proteins for sphingolipid hydrolases (saposins) are small acidic, heat-stable glycoproteins that stimulate the hydrolysis of sphingolipids by lysosomal enzymes. The molecular mass of each stimulator is about 10 kDa, but glycosylated forms of higher mass exist too.
Akira Sano, Shu-Ichi Ueno, Yasuo Kakimoto   +2 more
exaly   +3 more sources

Stimulation of lysosomal sphingomyelin degradation by sphingolipid activator proteins

Chemistry and Physics of Lipids, 1999
Lysosomal breakdown of glycosphingolipids with short hydrophilic carbohydrate headgroups is achieved by the simultaneous action of specific hydrolases and sphingolipid activator proteins (SAPs). Activator proteins are considered to facilitate the enzyme/substrate interaction between water-soluble enzymes and membrane-bound substrates.
Konrad Sandhoff, Thomas Linke, Klaus Ferlinz   +2 more
exaly   +3 more sources

Saposins (Sphingolipid Activator Proteins) in the Twitcher Mutant Mouse

Journal of Neurochemistry, 1990
Abstract: The twitcher mutant mouse, the animal model of Krabbe disease (human globoid cell leukodystrophy), is characterized by apparent deficiency of galactosylceramide β‐galactosidase activity. Saposin A and C, the heat‐stable small sphingolipid activator glycoproteins, stimulate the activity of galactosylceramide β‐galactosidase as well as ...
John S O'Brien, Hidenari Shigematsu
exaly   +3 more sources