Results 21 to 30 of about 10,573 (148)
Neuronal Ceroid Lipofuscinoses (NCLs) are progressive degenerative diseases mainly affect brain and retina. They are characterized by accumulation of autofluorescent storage material, mitochondrial ATPase subunit C, or sphingolipid activator proteins A ...
Xiao-Tun Ren +8 more
doaj +1 more source
International audienceSphingolipids are ubiquitous lipids found in all mammalian cell membranes and in plasma lipoproteins. Many exhibit dual functions, as key structural elements, but also as modulators of biological/physiological functions ...
Caillaud, Catherine +2 more
core +1 more source
Transcriptional profiling of the model organism "A. gossypii" : comparison of life cycle stages and transcription factor deletions [PDF]
Experiments described in this PhD thesis used for the rst time custom-made oligonucleotide chips to substantially increase our knowledge and understanding of the model organism A. gossypii. Four sets of experiments of different scales were performed:
Rischatsch, Riccarda
core +1 more source
Regulation of Mitogen-Activated Protein Kinases by Sphingolipid Products in Oligodendrocytes [PDF]
Sphingolipid products such as ceramide (cer), sphingosine (sph), and sphingosine-1-phosphate (SPP) are implicated in the regulation of cell growth and apoptosis. We have recently shown that cer, sph, and SPP differentially modulate ionic events in cultured oligodendrocytes (OLGs).
H, Hida +3 more
openaire +2 more sources
From FIC to BID : target identification and functional characterization of "Bartonella" effector proteins [PDF]
Pathogens belonging to the genus Bartonella employ a unique stealth infection strategy that involves evasion from the host immune system, replication in the endothelium and persistence in erythrocytes.
Pieles, Kathrin
core +1 more source
CPTP: A sphingolipid transfer protein that regulates autophagy and inflammasome activation [PDF]
The macroautophagy/autophagy and inflammasome pathways are linked through their roles in innate immunity and chronic inflammatory disease. Ceramide-1-phosphate (C1P) is a bioactive sphingolipid that regulates pro-inflammatory eicosanoid production. Whether C1P also regulates autophagy and inflammasome assembly/activation is not known. Here we show that
Shrawan Kumar Mishra +5 more
openaire +3 more sources
Do Sphingolipids Control Viral Membrane Protein Activity? [PDF]
The membrane-behaviour of the matrix (M) protein from respiratory syncytical virus, a prototypical enveloped virus, has been characterised by surface techniques (tensiometry, Brewster angle microscopy and atomic force microscopy) and experiments using lipid bilayers (FRET, light microscopy).
Sanderson, John M. +3 more
openaire +1 more source
Sphingolipid metabolism dysfunctions [PDF]
Sfingolipidi su glavne komponente staničnih membrana u živčanom sustavu svih eukariota. S obzirom da su uklopljeni u stanične membrane, oni kontroliraju i bitne stanične signalne puteve.
Hefer, Marija
core +1 more source
Upstream regulation of yeast TOR complexes [PDF]
Nitrogen is an essential component of living organism. Protein synthesis and biosynthesis of nitrogen containing molecules essential for growth, such as amino acids and NAD, strictly depend on the availability of the nitrogen source. Limiting amount of
Stracka, Daniele
core +1 more source
Analysis of the multiple forms of Gaucher spleen sphingolipid activator protein 2 [PDF]
Gaucher spleen sphingolipid activator protein 2 was fractionated into concanavalin A binding- and non-binding fractions. These fractions each contained several bands on non-denaturing polyacrylamide gel electrophoresis (PAGE). The two fractions were further fractionated by electroblotting the proteins from preparative gels onto nitrocellulose, staining
B C, Paton, A, Poulos
openaire +2 more sources

