Results 91 to 100 of about 1,668,348 (220)
Phytotherapy Research, EarlyView.Schematic overview of the multi‐target and multi‐pathway mechanisms of PDBI in the prevention and management of hypertension. ABSTRACT Hypertension remains a major global risk factor for cardiovascular diseases, yet current treatments face challenges such as suboptimal blood pressure control and inadequate organ protection.
Qiqi Deng +6 more
wiley +1 more source
Phytotherapy Research, EarlyView.ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
wiley +1 more source
Regulating Lipid Metabolism in Cancer: The Therapeutic Potential of Traditional Chinese Medicine
Phytotherapy Research, EarlyView.By regulating the reprogramming of lipid metabolism in tumor cells, TCM provides a novel strategy for antitumor therapy with reduced toxicity and enhanced efficacy. ABSTRACT Lipid metabolic reprogramming is a key feature of tumor cells to adapt to the microenvironment and plays an important role in tumor growth, invasion, and metastasis.
Yufeng Gao +11 more
wiley +1 more source
List of putative FFAT-like domains found in proteins related to the sphingolipid synthesis.
, 2018 List of putative FFAT-like domains found in proteins related to the sphingolipid synthesis.
Peter Mattjus (437084) +5 more
core +1 more source
Environmental Toxicology, EarlyView.ABSTRACT Fumonisin B1 (FB1), a mycotoxin commonly found in contaminated food and feed, has been increasingly implicated in neurotoxicity, although its mechanisms remain poorly understood. This study investigates the neurotoxic potential of FB1 in human SH‐SY5Y neuroblastoma cells, both undifferentiated and RA‐differentiated, and evaluates the ...
Gianluca Antonio Franco +6 more
wiley +1 more source
Environmental Toxicology, EarlyView.ABSTRACT Pancreatic cancer is the fourth leading cause of cancer deaths in the US and predicted to rise to second by 2030. Several risk factors have been identified as potential contributors to pancreatic cancer development including lifestyle factors and long‐term exposure to occupational and environmental carcinogens.
Barbara A. Hocevar, Lisa M. Kamendulis
wiley +1 more source
Investigating the Impact of Epstein-Barr Virus on Sphingolipid Composition in Extracellular Vesicles of Multiple Sclerosis Patients [PDF]
Background. Multiple sclerosis (MS) is a chronic autoimmune disease characterized by the immune system's attack on the central nervous system, leading to demyelination and neurodegeneration.
F. Martinelli Boneschi +13 more
core +2 more sources
Metabolome Diversity Enhances Resistance of Intertidal Clams to Thermal Stress
Integrative Zoology, EarlyView.Meretrix species are widely distributed intertidal bivalves in China with significant ecological and economic importance, which are sensitive to thermal stress. Our results showed that thermal environments of clam habitats shaped metabolome diversity, which can enhance the resistance of intertidal clams to thermal stress.
Zhi Hu +5 more
wiley +1 more source
Allergy, EarlyView.ABSTRACT The skin is far from a passive shield; it functions as a dynamic “living barrier” whose structural and immunological integrity is paramount in preventing atopic dermatitis (AD) and the subsequent progression of the atopic march toward food allergy (FA).
Klaudia Ryczaj +4 more
wiley +1 more source
, 2022 Plasma membrane (PM) carries out multiple functions a tightly regulated dynamic organization into specialized domains of different size, stability, and composition.
Santos, Filipa C.
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