Results 101 to 110 of about 10,624 (209)
Lithium ameliorates neural differentiation restoring cell death balance in Cornelia de Lange syndrome 2D and 3D models. [PDF]
Parodi C +20 more
europepmc +1 more source
Low molecular weight proteins in secondary lysosomes as activators of different sphingolipid hydrolases [PDF]
Mraz, W., Fischer, G., Jatzkewitz, H.
openaire +2 more sources
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer +5 more
wiley +1 more source
Reconstruction of Molecular Interaction Patterns from Endolysosomes in Ceramide-Depleted Cells. [PDF]
Feng Y +7 more
europepmc +1 more source
ABSTRACT Glioblastoma (GBM) is a markedly heterogeneous intracranial tumor characterized by poor prognosis. While distinctive glycolysis and cholesterol synthesis capacities exist within its microenvironment, comprehensive profiling of these metabolic traits remains lacking.
Zheng Hu +4 more
wiley +1 more source
Lipid metabolic dysregulation in diabetic kidney disease: mechanisms, cellular impact, and therapeutic strategies. [PDF]
Wang Y +10 more
europepmc +1 more source
Abstract Objective Epilepsy is a prevalent chronic neurological disorder characterized by abnormal neuronal electrical activity. The primary treatment modality for individuals with epilepsy (PWE) is antiseizure medication (ASM). The multiple potential factors contributing to treatment resistance in epilepsy may be attributed to the inability of ASMs to
Priya Kannan Varshini +9 more
wiley +1 more source
Sphingolipid metabolism-related genes B4GALNT1 and CERS4 as prognostic biomarkers in lung adenocarcinoma. [PDF]
Jeon J +6 more
europepmc +1 more source
This review provides a comprehensive, engineering‐oriented synthesis of postbiotics as next‐generation functional food ingredients. It first outlines the principal production routes for postbiotic generation, encompassing thermal technologies, non‐thermal technologies, and extraction/purification methods, and subsequently examines the analytical and ...
Tansu Taspinar, Nuray Güzeler
wiley +1 more source
Intestinal bacteria trigger a hibernation-like state in homotherms via the gut-brain axis. [PDF]
Bao Z +10 more
europepmc +1 more source

