Results 41 to 50 of about 10,573 (148)
Saposin C is required for lipid presentation by human CD1b.
, 2004 Lipids from Mycobacterium tuberculosis are presented through CD1 proteins to T lymphocytes in humans, but the accessory molecules required for antigen loading and presentation remain unidentified.
Sandhoff, Konrad +28 more
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Molecular Basis of Genetic Sphingolipid Activator Protein Deficiencies.
Trends in Glycoscience and Glycotechnology, 1994 通常はリソソーム内に局在している一連の比較的小さな糖タンパク質が、短い親水性の先端基をもったスフィンゴ糖脂質の生理的分解の補助因子として機能する。GM2活性化因子タンパク質の遺伝子欠損では、テイサックス病の古典的幼児型と本質的に区別できない臨床上および生化学上の表現型になる。ヒトの第5染色体上にあるある単一遺伝子がGM2活性化因子タンパク質をコードする。2つの相同タンパク質sap-Bおよびsap-Cの遺伝子欠損は、それぞれ異染性白質萎縮症およびゴーシェ病と似ている障害を引き起こす。さらに2つの推定上の活性化因子タンパク質sap-A、sap-Dも、in vitro でいくつかのスフィンゴ脂質の分解を活性化することが知られている。しかしながら、in vivo のsap-A、sap ...
openaire +2 more sources
, 1983 sosomal enzymes requires the presence of additional proteins, which have been called activator proteins. The number of activator proteins, their specificity, exact mechanism of action, and response to a storage process all remain to be determined.
Koji Inui, David A. Wenger
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, 2006 Includes bibliographical references (leaves 150-177).Ischemic preconditioning is a protective mechanism whereby repetitive transient ischaemia confer protection against the subsequent prolonged lethal ischaemia that is observed during myocardial ...
Suleman, Naushaad
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, 2017 p21-activated kinase 1 (Pak1) is a member of the highly conserved family of serine/threonine protein kinases regulated by Ras-related small G-proteins, Cdc42/Rac1. It has been previously demonstrated to be involved in cardiac protection.
Wang, X +21 more
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The mechanism of signal transduction by the GPI anchored Prod 1 protein
, 2010 Salamanders such as the red spotted newt Notophthalamus viridescens and the axolotl Ambystoma mexicanum regenerate a number of anatomical structures following injury.
Blassberg, R.A.
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, 2015 The discoveries of specific protein storage in the NCLs, particularly of subunit c of ATP synthase in most, and the sphingolipid activator proteins, SAPs or saposins A and D in CLN1, CLN10 and an unassigned form are reviewed.
Palmer, DN, Palmer, David N.
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The role of Toll-like receptor 4 (TLR-4) in wine-induced cardioprotection
, 2012 Includes abstract.Includes bibliographical references.Moderate and chronic consumption of red wine confers cardioprotection. Melatonin, present in wine, may contribute to this cardioprotective effect. Melatonin confers cardioprotection via the activation
Albertyn, Zulfah
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