Results 91 to 100 of about 2,043,660 (241)

A lipid‐sensitive food choice behavior influences aging outcomes from a longevity‐promoting diet

The FEBS Journal, EarlyView.
C. elegans are exposed to a variety of bacteria in their natural environment and must be able to distinguish between beneficial and detrimental food sources. We show that C. elegans exposed to the bacterium from their natural habitat, Methylobacterium, disrupts lipid homeostasis, causing worms to avoid this bacterial species and choose the laboratory ...
Nicole L. Stuhr, Carmen M. Ramos, Chris D. Turner, Alexander A. Soukas, Sean P. Curran   +4 more
wiley   +1 more source

Modulation of sebocyte function in acne: A pathway‐inclusive review

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Acne is multifactorial, with the sebocyte acting as a central immunometabolic hub linking lipogenic, inflammatory, hormonal and barrier pathways. Mapping established and investigational therapies onto this sebocyte‐centred model offers a mechanism‐based framework that complements existing treatment paradigms and may guide more targeted, antibiotic ...
Christos C. Zouboulis, Apostolos Pappas, Katja Martin, Mauro Picardo   +3 more
wiley   +1 more source

Mortality in Salmon (Salmo salar) Fry Related to Lipoid Liver Disease Induced by Unbalanced Fatty Acid Composition of the Diet

Journal of Fish Diseases, EarlyView.
ABSTRACT In 2023, all but one Swedish restocking farm rearing Baltic salmon and sea trout fry experienced massive mortality caused by lipoid liver disease (LLD). The struck farms used the same feed, and this was suspected to be the cause of the outbreak.
Caroline Ek, Lo Persson, Charlotte Axén
wiley   +1 more source

Established and Emerging Biomarkers to Characterize Persons at Risk for Obesity—Paving the Way for Targeted Clinical Intervention Trials—A Comprehensive Position Paper

Obesity Reviews, EarlyView.
ABSTRACT Despite all efforts, obesity remains a major health concern worldwide, with continuously increasing rates, affecting approx. 14% of the total world population, being as high as 43% in some countries. As obesity is related to numerous comorbidities, including type 2 diabetes, cardiovascular diseases, and some types of cancer, the consequences ...
Farhad Vahid, Victoria Stopa, Laurent Malisoux, Yvan Devaux, Elsa Lamy, Fernando Capela e Silva, Sarah Forberger, Tiziana de Magistris, Antoni Sureda, Margalida Monserrat‐Mesquida, Maria Pérez‐Jiménez, Rajini Nagrani, Maria Giovanna Onorati, Michele Filippo Fontefrancesco, Jonathan Turner, Mahesh S. Desai, Josep Tur, Cristina Bouzas, Gino Gabriel Bonetti, Oliver Riedel, Gitte Ravn‐Haren, Rikke Andersen, Torsten Bohn   +22 more
wiley   +1 more source

Investigating Overweight and Obesity Risk in Shift Workers Using Omics Technologies

Obesity Reviews, EarlyView.
ABSTRACT Night shift workers are at higher risk of developing overweight and obesity. The disruption of the physiological circadian rhythm leads to metabolic alterations, such as decreased insulin sensitivity, increased adipogenesis, and inflammation, with effects on their health and leading, among other diseases, to obesity.
Katrin Scionti, Ivana Václavková, Vanessa Schoissengeier, Karl‐Heinz Wagner   +3 more
wiley   +1 more source

Hidden Strategies Beneath a Single Nucleotide: Contrasting Physiology in Lichen Photobiont Strains

Plant, Cell &Environment, EarlyView.
ABSTRACT Lichen photobionts exhibit significant physiological variability with important ecological implications. While this variability is relatively well studied at the interspecific level, it has rarely been examined at the intraspecific level. Here, we investigated the physiological responses to temperature and irradiance of two Trebouxia lynniae ...
Miguel Blázquez, David Pizarro, Ana García‐Muñoz, Raquel Pino‐Bodas, Asunción de los Ríos, Miren I. Arzac, José Ignacio García‐Plazaola, Beatriz Fernández‐Marín, Unai Artetxe, Rosa Toledo‐Gil, Fernando Vallejo, Leonardo M. Casano, Israel Pérez‐Vargas, Sergio Pérez‐Ortega, Francisco Gasulla   +14 more
wiley   +1 more source

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

Periodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad, Nima Farshidfar, Nathan E. Estrin, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +6 more
wiley   +1 more source

Inflammatory response and its relation to sphingolipid metabolism proteins: Chaperones as potential indirect anti-inflammatory agents

, 2019
Lysosome is the organelle responsible for breaking down macromolecules to maintain homeostasis and to fight infection. The disruption of normal lysosomal function due to mutations in the sphingolipid metabolism proteins leads to a class of lysosomal ...
Hatice Asuman Ozkara, Yagci, Z. Begum, Z. Begum Yagci, Elif Esvap, Elif Ozkirimli Olmez, ÖZKIRIMLI ÖLMEZ, ELİF, ÖZKARA, HATİCE ASUMAN, Olmez, Elif Ozkirimli, Esvap, Elif, Kutlu O. Ulgen, Ulgen, Kutlu O.   +10 more
core   +1 more source

Periodontitis and metabolic dysfunction‐associated steatotic liver disease

Periodontology 2000, EarlyView.
Abstract Objective Periodontitis is a chronic inflammatory disease with systemic effects that extend beyond the oral cavity and contribute to systemic immune and metabolic dysregulation. Chronic liver diseases, particularly metabolic dysfunction‐associated steatotic liver disease (MASLD) and its progressive phenotypes, have emerged as major global ...
Rafael Scaf de Molon, Erica Dorigatti de Avila, Davi da Silva Barbirato, Mariana Fampa Fogacci, Jamil Awad Shibli, Anton Sculean, Alpdogan Kantarci   +6 more
wiley   +1 more source

Endosome and Golgi‐associated degradation ( EGAD ) of membrane proteins regulates sphingolipid metabolism

, 2019
International audienceCellular homeostasis requires the ubiquitin-dependent degradation of membrane proteins. This was assumed to be mediated exclusively either by endoplasmic reticulum-associated degradation (ERAD) or by endosomal sorting complexes ...
Oliver Schmidt, Peter, Matthias,, Peter, Matthias, H, Angelova, Mihaela, Fröhlich, Florian, Sebastian Eising, Baumann, Verena, Weyer, Yannick, Schleiffer, Alexander, Peter, Matthias, Widerin, Michael,, Teis, David, Widerin, Michael, A, Schmidt, Oliver, Lindner, Herbert, Matthias Peter, Yannick Weyer, Mihaela Angelova, Herbert Lindner, Michael A Widerin, Kremser, Leopold, Leopold Kremser, Verena Baumann, Alexander Schleiffer, Widerin, Michael A., Florian Fröhlich, Eising, Sebastian, David Teis, Weyer Y, Peter M, Teis D, Schmidt O, Eising S, Kremser L, Angelova M, Fröhlich F, Widerin MA, Lindner H, Schleiffer A, Baumann V   +39 more
core   +1 more source