Results 161 to 170 of about 78,947 (270)

Multi-omics analysis reveals that FABP2 suppresses colorectal cancer progression by regulating sphingomyelin metabolism via the PPAR signaling pathway. [PDF]

open access: yesCancer Cell Int
Wang P   +11 more
europepmc   +1 more source

Circulating Rhythmic Metabolites and Causal Risk of Type 2 Diabetes in Adults in the Canadian Longitudinal Study on Aging

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 4243-4252, May 2026.
ABSTRACT Aims Circadian regulation of metabolism is an important factor in metabolic health, yet the role of rhythmic metabolites in Type 2 diabetes development remains poorly understood. This study investigated associations between circulating rhythmic metabolites and incident Type 2 diabetes risk and evaluated causal relationships using two‐sample ...
Divya Joshi   +10 more
wiley   +1 more source

Metabolomic responses are more sensitive in muscle than serum following 28 days of arduous exercise with erythropoietin administration

open access: yesExperimental Physiology, Volume 111, Issue 5, Page 2613-2626, 1 May 2026.
Abstract Erythropoietin (EPO) administration stimulates haematological and non‐haematological adaptations that alter substrate oxidation and enhance aerobic performance. The effects of strenuous exercise and EPO on metabolites, and whether any effect is associated with haematological and non‐haematological adaptations, has not been assessed.
Devin J. Drummer   +11 more
wiley   +1 more source

SPHINGOMYELIN

open access: yesJournal of Biological Chemistry, 1913
openaire   +1 more source

Maternal Choline Supplementation in a Mouse Model of Down Syndrome and Alzheimer’s Disease Generates Unique Expression Profile Mosaics Within Three Hippocampal Excitatory Neuronal Populations

open access: yesThe FASEB Journal, Volume 40, Issue 7, 15 April 2026.
Maternal choline supplementation (MCS) is utilized in the Ts65Dn mouse model of Down syndrome (DS) and Alzheimer's disease (AD). At ~6 months of age, laser capture microdissection and single population RNA‐sequencing of three hippocampal neuron populations (CA1 and CA3 pyramidal neurons and dentate gyrus granule cells) were conducted.
Melissa J. Alldred   +8 more
wiley   +1 more source

Ceramide metabolism in oxidative and glycolytic muscle: Significance for lipid-induced insulin resistance. [PDF]

open access: yesMol Metab
Eurén T   +12 more
europepmc   +1 more source

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