Results 151 to 160 of about 62,442 (260)

Extracellular Vesicle‐Bound Bacterial Toxin Pneumolysin Triggers Membrane Engagement and Damage Beyond Canonical Pore Formation

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
Bacterial toxin hijacks host microvesicles to breach cell membranes Microvesicles derived from challenged host cells carrying the pneumococcal pore‐forming toxin pneumolysin promote fusion with target cells and membrane permeabilisation. Our integrated experimental and computational study reveals a mechanism by which PLY‐lipid interactions enable ...
Aswathy C. Sagilkumar, Avinashi Lal Kushwaha, Anushka Shitut, Dheeraj Kumar Sarkar, Sruthika Sukumar, Subhajit Mahanty, Somnath Dutta, Jagannath Mondal, Karthik Subramanian   +8 more
wiley   +1 more source

Causal Effects of Oral Microbiome, Circulating Metabolites, and Inflammatory Proteins on Recurrent Aphthous Stomatitis: A Two-Sample Mendelian Randomization Study. [PDF]

Oral Health Prev Dent
Long S, Zeng W, Huang S, Yang L, Zhou R, Zhu K, Zhu X.   +6 more
europepmc   +1 more source

The Role of EVs in the Aging Hematopoietic System

Aging Cell, Volume 25, Issue 10, October 2026.
Extracellular vesicles from aged bone marrow carry pro‐inflammatory cargo that drives blood stem cell decline, while youthful vesicles restore or maintain stem cell function. Circulating vesicles therefore represent both a readout of hematopoietic aging and a potential therapeutic route.
Esra G. Kosebent, Nathalie Havranek, Karoline Kollmann, Kristina Kirschner, Eszter Doma, Kavya Gupta   +5 more
wiley   +1 more source

Initial Molecular Detection of Membrane Damage in Post-Golgi Compartments. [PDF]

Cells
Shiba Y, Saito N.
europepmc   +1 more source

A SIMPLIFIED PREPARATION OF SPHINGOMYELIN

Journal of Biological Chemistry, 1958
M M, RAPPORT, B, LERNER
openaire   +2 more sources

Association Between the Root Canal Microbiome and Apical Lesion Size: An Observational Shotgun Metagenomic Study

International Endodontic Journal, Volume 59, Issue 10, Page 2211-2222, October 2026.
ABSTRACT Aim The aim was to characterize the taxonomic and functional composition of the microbiome involved in primary endodontic infections and to evaluate their association with the periapical lesion size using shotgun metagenomic sequencing. Methodology Samples from primary root canal infections diagnosed with apical periodontitis were analysed ...
Virginia Pérez‐Carrasco, David Uroz‐Torres, Ana Soriano‐Lerma, Miguel Soriano, Jose Antonio García‐Salcedo, Maria Teresa Arias‐Moliz   +5 more
wiley   +1 more source

Integrating untargeted metabolomics and machine learning to reveal an aberration of sphingolipid metabolism in cardiometabolic HFpEF. [PDF]

Diabetol Metab Syndr
Mao X, Zhao L, Liu P, Wang Y, Shi S, Song Q.   +5 more
europepmc   +1 more source

Malaria mosquito antimicrobial defence requires immunity and detoxification gene regulation by Lola

Insect Molecular Biology, Volume 35, Issue 5, Page 576-593, October 2026.
Malaria mosquito antimicrobial defence requires upregulation of lola. Attenuation of lola in the midgut of Anopheles albimanus mosquitoes inhibits the upregulation of immunity genes induced by challenge. Putative target genes of the Lola transcription factor were revealed by lola attenuation, including Cecropin‐C, Draper, PPAF2, Clip‐domain serine ...
Heidi Espadas‐Álvarez, Verónica Valverde‐Garduño   +1 more
wiley   +1 more source

The Enzymatic Synthesis of Sphingomyelin

Journal of Biological Chemistry, 1958
M, SRIBNEY, E P, KENNEDY
openaire   +2 more sources

Acute exercise‐induced lipolysis and increase in levels of fatty acid esters of hydroxy fatty acids in adipose tissue are impaired in obese and aged mice

Experimental Physiology, Volume 111, Issue 10, Page 4457-4497, 1 October 2026.
Abstract Improving adipose tissue (AT) metabolism through exercise might increase production of lipokines from the fatty acid esters of hydroxy fatty acids (FAHFA) family. Although exercise training can increase insulin sensitivity and levels of specific FAHFA in AT and the circulation in humans, the effects of acute exercise on FAHFA levels remain ...
Marko Mitrovic, Olga Horakova, Martin Riecan, Veronika Kleinova, Tomas Cajka, Lenka Rossmeislova, Ondrej Kuda, Martin Rossmeisl   +7 more
wiley   +1 more source