Results 191 to 200 of about 52,176 (275)

Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines

open access: yesAdvanced Science, Volume 12, Issue 31, August 21, 2025.
This review offers a comprehensive overview of pharmaceutical nanotechnology strategies to address limitations associated with the complex material basis and relative mild therapeutic efficacy of Chinese herbal medicines, and summarizes the advantages of these strategies.
Jiameng Li   +11 more
wiley   +1 more source

Lipid profiling reveals unsaturated lipid reduction in women with Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 21, Issue 8, August 2025.
Abstract INTRODUCTION Alzheimer's disease (AD) is a devastating neurological disease that disproportionately affects women. This study aimed to investigate sex‐specific single lipids associated with AD. METHODS Plasma samples from 841 participants, comprising 306 individuals with AD, 165 with mild cognitive impairment (MCI), and 370 cognitively healthy
Asger Wretlind   +7 more
wiley   +1 more source

Cell type specific localization of sphingomyelin biosynthesis [PDF]

open access: bronze, 2000
Farsaneh Sadeghlar   +2 more
openalex   +1 more source

Exploring 1400 Plasma Metabolites and Polycystic Ovary Syndrome: A Bidirectional Mendelian Randomization Study

open access: yesBrain and Behavior, Volume 15, Issue 8, August 2025.
Bidirectional Mendelian randomization found 15 plasma metabolites that increase PCOS risk, such as methionine sulfoxide, N‐acetylserine, and glycine, and 13 that offer protection, including threonate, 7‐methylguanine, and theophylline. These results suggest new therapeutic targets for addressing metabolic dysfunction in PCOS.
Xiaoli Lei   +3 more
wiley   +1 more source

N6‐methyladenosine‐regulated exosome biogenesis orchestrates an immunosuppressive pre‐metastatic niche in gastric cancer peritoneal metastasis

open access: yesCancer Communications, Volume 45, Issue 8, Page 941-965, August 2025.
Abstract Background Gastric cancer peritoneal metastasis is clinically challenging, given the limited treatment options and poor prognosis. The molecular mechanisms that precede gastric cancer peritoneal metastasis, known as the pre‐metastatic niche (PMN), and its relationship with N6‐methyladenosine (m6A) modification remain unclear.
Song Li   +23 more
wiley   +1 more source

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