Selection of Host Plasma Membrane Lipids by HIV‐1 Gag Protein
Enrichment of sphingomyelin in the HIV‐1 envelope arises from Gag binding to PI(4,5)P2, which triggers reorganization of plasma membrane sphingomyelin/cholesterol domains through unknown mechanisms. We propose that cholesterol‐mediated interleaflet coupling between sphingomyelin and PI(4,5)P2, rather than interdigitation, underlies Gag‐induced lipid ...
Nario Tomishige +2 more
wiley +1 more source
Fluorescent Dyes for Probing Intracellular and Subcellular Polarity
Fluorescent probes are crucial tools for measuring cellular microenvironment polarity, a parameter that influences physiological organelle function and diseases such as cancer. This text details the probes' physicochemical principles, intracellular targeting strategies, and key photophysical parameters for polarity estimation.
M. Carmen Gonzalez‐Garcia +4 more
wiley +1 more source
Altered Sphingolipids, Glycerophospholipids, and Lysophospholipids Reflect Disease Status in Idiopathic Steroid-Sensitive Nephrotic Syndrome in Children: A Non-Targeted Metabolomic Study. [PDF]
Kanai T +11 more
europepmc +1 more source
Plasma sphingomyelin levels were negatively correlated with ferritin levels in splenectomized thalassemia patients [PDF]
Yeşim Öztaş +5 more
openalex +1 more source
Extracellular vesicles carry proteins, lipids and metabolites, reflecting cellular health and disease. This review examines how mass spectrometry‐based multi‐omics—proteomics, lipidomics and metabolomics is transforming EV characterisation. We address integration strategies, standardisation challenges and emerging technologies, bridging multi‐omics ...
Akila Wijerathna‐Yapa +2 more
wiley +1 more source
Sphingomyelin synthase inhibitors from edible mushrooms prevent overweight and improve vitamin D homeostasis in a mouse model of diet-induced obesity. [PDF]
Enkhbat E +7 more
europepmc +1 more source
Microbiota-sphingolipid pathway in generalized epilepsy: evidence from Mendelian randomization and clinical metabolomics. [PDF]
Gong J +9 more
europepmc +1 more source
Lysenin, a Sphingomyelin-Binding Protein: its Role in the Activation of Platelets
Kazuhiko Haruta +6 more
openalex +2 more sources
Lecithin—Sphingomyelin Ratio in Amniotic Fluid, as Assessed by a Modified Thin-Layer Chromatographic Method in Which a Commercial Pre-Coated Plate Is Used [PDF]
Valyacheri R Mallikarjuneswara
openalex +1 more source
Mitigation of Metabolic Diseases Through Personalized Nutrition: A Critical In‐Depth Review
The main objective of this review is to explore the impact of variation within the microbiome and among genes on nutrient metabolism and argue in favor of successful evidence of individualized dietary intervention for cardiovascular disease, diabetes, and obesity.
Muhammad Tayyab Arshad +7 more
wiley +1 more source

