Results 181 to 190 of about 9,105 (228)

Inhibitors of the sphingomyelin cycle: Sphingomyelin synthases and sphingomyelinases

Chemistry and Physics of Lipids, 2016
Sphingolipids are a class of bioactive lipids, which are key modulators of an increasing number of physiologic and pathophysiologic processes that include cell cycle, apoptosis, angiogenesis, stress and inflammatory responses. Sphingomyelin is an important structural component of biological membranes, and one of the end-points in the synthesis of ...
Mohamad, Adada, Chiara, Luberto, Daniel, Canals   +2 more
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Molecular packing in sphingomyelin bilayers and sphingomyelin/phospholid mixtures

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2003
The molecular packing properties of sphingomyelin (SM) from egg yolk were studied. The influence of the spontaneous curvature of SM on the phase behaviour of SM/dodecane/water systems was investigated. A comparison was made to a previous study by Lindblom et al. (Liq. Cryst. 3 (1988) 783), of the phase behaviour of dipalmitoylphosphatidylcholine (DPPC)/
Tomas, Byström, Göran, Lindblom
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Sphingomyelin metabolites inhibit sphingomyelin synthase and CTP:phosphocholine cytidylyltransferase

American Journal of Physiology-Lung Cellular and Molecular Physiology, 2001
Tissue injury in inflammation involves the release of several cytokines that activate sphingomyelinases and generate ceramide. In the lung, the impaired metabolism of surfactant phosphatidylcholine (PC) accompanies this acute and chronic injury. These effects are long-lived and extend beyond the time frame over which tumor necrosis factor (TNF)-α and ...
J, Vivekananda, D, Smith, R J, King
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Interbilayer interactions between sphingomyelin and sphingomyelin/cholesterol bilayers

Biochemistry, 1992
Pressure versus fluid spacing relations have been obtained for sphingomyelin bilayers in the gel phase and equimolar sphingomyelin/cholesterol in the liquid-crystalline phase by the use of X-ray diffraction analysis of osmotically stressed aqueous dispersions and oriented multilayers.
T J, McIntosh, S A, Simon, D, Needham, C H, Huang   +3 more
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Estimation of Sphingomyelin

Nature, 1965
AN investigation of marine phospholipids in this laboratory necessitated the determination of Sphingomyelin. Sphingomyelin is frequently estimated by determining sphingosine according to the method of McKibbin and Taylor1. This method consists of the separation of sphingosine from other nitrogenous bases by extraction from an aqueous acid solution with
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Interaction of glucagon with sphingomyelins

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1982
Abstract In the presence of either egg or bovine brain sphingomyelin, the spectral properties of glucagon undergo changes which are similar to those which occur in the presence of synthetic phosphatidylcholines. The fluorescence emission spectra are blue shifted about 10 nm in the presence of lipid and the peptide acquires an increased helical ...
R M, Epand, L T, Boni, S W, Hui
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THE ISOLATION OF BEEF SPHINGOMYELINS

Canadian Journal of Biochemistry, 1964
A method was developed for the quantitative isolation of tissue sphingomyelins. Total lipid extracts of tissues were subjected to selective hydrolysis to destroy ester phosphatides and plasmalogens. The water-soluble hydrolysis products were removed by solvent fractionation.
W A, SPENCER, R, SCHAFFRIN
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