Results 191 to 200 of about 9,105 (228)
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Regulation of sphingomyelin metabolism
Pharmacological Reports, 2016Sphingolipids (SFs) represent a large class of lipids playing diverse functions in a vast number of physiological and pathological processes. Sphingomyelin (SM) is the most abundant SF in the cell, with ubiquitous distribution within mammalian tissues, and particularly high levels in the Central Nervous System (CNS).
Kamil Bienias +4 more
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Biochemistry, 1997
In this study, we examine the phase behavior as well as lateral diffusion and percolation in the region of coexisting gel and fluid phases in binary mixtures composed of dimyristoylphosphatidylcholine and one of two totally synthetic D-erythro-sphingomyelins (having either C16 or C24 acyl chains, both having similar gel to liquid-crystalline phase ...
L K, Bar, Y, Barenholz, T E, Thompson
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In this study, we examine the phase behavior as well as lateral diffusion and percolation in the region of coexisting gel and fluid phases in binary mixtures composed of dimyristoylphosphatidylcholine and one of two totally synthetic D-erythro-sphingomyelins (having either C16 or C24 acyl chains, both having similar gel to liquid-crystalline phase ...
L K, Bar, Y, Barenholz, T E, Thompson
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Biological functions of sphingomyelins
Progress in Lipid Research, 2013Sphingomyelin (SM) is a dominant sphingolipid in membranes of mammalian cells and this lipid class is specifically enriched in the plasma membrane, the endocytic recycling compartment, and the trans Golgi network. The distribution of SM and cholesterol among cellular compartments correlate.
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Meconium has no lecithin or sphingomyelin but affects the lecithin/sphingomyelin ratio
American Journal of Obstetrics and Gynecology, 1998Although a few studies have evaluated the effect of meconium on the lecithin/sphingomyelin ratio for testing of fetal lung maturity, to date these studies have assessed only the lecithin-sphingomyelin ratio of amniotic fluid contaminated with meconium.
S A, Longo +4 more
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2020
Sphingolipids play important roles in apoptosis, differentiation, senescence, proliferation, and inflammation. The sphingomyelin (SM) cycle, with the key components of SM, sphingomyelinase (SMase) and ceramide, has received substantial attention to date because of its role in cell signaling.
Heather Hayter, Yusuf A. Hannun
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Sphingolipids play important roles in apoptosis, differentiation, senescence, proliferation, and inflammation. The sphingomyelin (SM) cycle, with the key components of SM, sphingomyelinase (SMase) and ceramide, has received substantial attention to date because of its role in cell signaling.
Heather Hayter, Yusuf A. Hannun
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Chemistry and Physics of Lipids, 2008
For drug delivery purpose the anticancer drug S12363 was loaded into ESM/Chol-liposomes using either a pH or an ammonium gradient. Association between the drug and the liposome depends markedly on the liposome membrane structure. Thus, ESM and ESM/Chol bilayer organization had been characterized by coupled DSC and XRDT as a function of both cholesterol
Caroline, Chemin +6 more
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For drug delivery purpose the anticancer drug S12363 was loaded into ESM/Chol-liposomes using either a pH or an ammonium gradient. Association between the drug and the liposome depends markedly on the liposome membrane structure. Thus, ESM and ESM/Chol bilayer organization had been characterized by coupled DSC and XRDT as a function of both cholesterol
Caroline, Chemin +6 more
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A sphingomyelin shield for flaviviruses
Science SignalingSphingomyelins in mosquito saliva enhance flavivirus infection by preventing viral protein degradation.
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