Results 141 to 150 of about 31,038,441 (242)

Generation of Allogeneic CAR‐T Circumvents Functional Deficits in Patient‐Derived Autologous Product for Glioblastoma

International Journal of Cancer, Volume 159, Issue 6, Page 1521-1534, 15 September 2026.
Clinical trials of chimeric antigen receptor T‐cell (CAR‐T) therapies in glioblastoma have shown limited clinical benefits. Whether this may be explained by the basal quality of CAR‐T products, which are currently generated using patient, autologous T‐cells, has been little explored.
Sabra K. Salim, Muhammad Vaseem Shaikh, Jeffrey Wei, William T. Maich, Alisha Anand, Oliver Y. Tang, Minomi K. Subapanditha, Zahra Alizada, Yujin Suk, Manoj Singh, Kui Zhai, Aapti Khanna, Benjamin Brakel, Vassil Dimitrov, Zoya Tabunshchyk, Katie Chan, Kevin R. Brown, Parvez Vora, Donald M. O'Rourke, Zev A. Binder, Chitra Venugopal, Jason Moffat, Sheila K. Singh   +22 more
wiley   +1 more source

Sphingosine 1-phosphate receptor [PDF]

Science-Business eXchange, 2012
openaire   +1 more source

Sphingosine-1-phosphate receptor 1/5 selective agonist alleviates ocular vascular pathologies

Scientific Reports
Ocular abnormal angiogenesis and edema are featured in several ocular diseases. S1P signaling via S1P1 likely is part of the negative feedback mechanism necessary to maintain vascular health.
Shinsuke Nakamura, Rie Yamamoto, Takaya Matsuda, Hiroto Yasuda, Anri Nishinaka, Kei Takahashi, Yuki Inoue, Sadao Kuromitsu, Masamitsu Shimazawa, Masahide Goto, Shuh Narumiya, Hideaki Hara   +11 more
doaj   +1 more source

Pharmacological blockade of G-protein coupled receptors : interventions to alter expression or internalization [PDF]

, 2004
Hangartner, Christoph
core   +1 more source

Safety, pharmacokinetics and pharmacodynamics of NXC736, a novel sphingosine-1-phosphate receptor modulator. [PDF]

Br J Clin Pharmacol
Chung WK, Kim H, Park Y, Lee BY, Yu KS, Lee SH.   +5 more
europepmc   +1 more source

Sphingosine-1-Phosphate Receptor 1 Regulates Competition Dependent Astrocyte Morphogenesis and Tiling in Murine Cortex. [PDF]

Glia
Gonzales JPM, Tuck C, Thumu SCR, Munir S, Harris J, Tariq HZ, Marcelli P, Dominguez O, Anbazagan KS, Singh SK.   +9 more
europepmc   +1 more source

Fungal Infections Associated with Sphingosine 1-Phosphate Receptor Modulators: Immunological Mechanisms, Clinical Patterns, and Management Considerations. [PDF]

Microorganisms
Yazdan KM, Madam ST, Pasula S.
europepmc   +1 more source

Correction: Sphingosine-1-phosphate receptor 1/5 selective agonist alleviates ocular vascular pathologies. [PDF]

Sci Rep
Nakamura S, Yamamoto R, Matsuda T, Yasuda H, Nishinaka A, Takahashi K, Inoue Y, Kuromitsu S, Shimazawa M, Goto M, Narumiya S, Hara H.   +11 more
europepmc   +1 more source

Effects of sphingosine-1-phosphate receptor modulators on remyelination in multiple sclerosis: evidence from <i>in vitro</i> experiments, animal models and human studies. [PDF]

Front Immunol
Ricigliano VAG.
europepmc   +1 more source

Sphingosine-1-phosphate receptor 1 signaling stimulates human pluripotent stem cell-derived cardiomyocyte differentiation and maturation. [PDF]

Exp Mol Med
Yu WD, Lee SG, Jung KB, Hyun SA, Kim YD, Son YS, Lee H, Cho HS, Kim DS, Lee KJ, Yoo J, Kim CY, Lee MO, Kwon O, Son MY.   +14 more
europepmc   +1 more source