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Journal of Gastroenterology and Hepatology, Volume 41, Issue 2, Page 686-695, February 2026.ABSTRACT Background Aberrant T‐helper 1 (Th1) and Th17 cell activation is involved in the pathogenesis of inflammatory bowel disease (IBD). Psychosine is known to induce apoptosis, promote astrocyte activation, and inhibit osteoclastogenesis. However, the role of psychosine on Th1 and Th17 cell immune responses has not been previously reported. In this
Ritian Lin +4 more
wiley +1 more source
A Somatic Mutation in HIF‐2α Affects Glucose and Lipid Metabolism via CD36 and Ceramide
The FASEB Journal, Volume 40, Issue 1, 15 January 2026.A mutation within the C‐terminal transactivation domain of HIF‐2α enhances Cd36 expression by increased transactivation activity, leading to ceramide accumulation and disruption of glucose and lipid metabolism. Inhibition of ceramide synthesis by myriocin reduces ceramide levels and ameliorates these metabolic disturbances.
Feiqiong Gao +9 more
wiley +1 more source
Sphingosine 1-phosphate receptor (S1PR) [PDF]
Science-Business eXchange, 2009 openaire +1 more source
PET study of sphingosine-1-phosphate receptor 1 expression in response to vascular inflammation in a rat model of carotid injury [PDF]
, 2017 Abendschein, Dana R +6 more
core +2 more sources