Results 271 to 280 of about 102,609 (313)
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Sphingosine in apoptosis signaling
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2002The sphingolipid metabolites ceramide, sphingosine, and sphingosine 1-phosphate contribute to controlling cell proliferation and apoptosis. Ceramide and its catabolite sphingosine act as negative regulators of cell proliferation and promote apoptosis. Conversely, sphingosine 1-phosphate, formed by phosphorylation of sphingosine by a sphingosine kinase,
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Alteration of Lymphocyte Trafficking by Sphingosine-1-Phosphate Receptor Agonists
Science, 2002Suzanne M. Mandala +15 more
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Glycosphingolipids (Sugar-Sphingosine Conjugates)
1969Publisher Summary Glycosphingolipids are a group of sphingolipids containing mono or oligosaccharide residues. The sugar residues are in direct or indirect glycosidic conjugation with the primary hydroxyl group of the N -acylated sphingosine or dihydrosphingosine molecule.
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Mfsd2b is essential for the sphingosine-1-phosphate export in erythrocytes and platelets
Nature, 2017T. M. Vu +14 more
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Sphingosine and Sphingosine 1 Phosphate in the Brain
2011Sphingosine is an 18-carbon amino alcohol with an unsaturated hydrocarbon chain. It is found in sphingolipids (cerbroside, sulfatide, and ganglioside) as well as phospholipid (sphingomyelin) (Fig. 9.1). Sphingomyelin (SM) is the major membrane sphingolipid and is the precursor for ceramide and sphingosine.
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Sphingosine 1-phosphate receptor-targeted therapeutics in rheumatic diseases
Nature Reviews Rheumatology, 2022Nathalie Burg, Timothy T Hla
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